Sentences with phrase «of immunocompromised mice»

Furthermore, the transplantation and subsequent engraftment of 3D - cultured skeletal muscle tissue into the endogenous muscles of immunocompromised mice led to high levels of vascularization and maintained muscle functionality.

Not exact matches

As proof - of - principle of the potential efficacy, Zhang's team grew human ovarian tumors in immunocompromised mice, then injected short - interfering RNAs to block the tumors» growth using RNA interference against FAL1.

Because mice with intact immune systems are resistant to S. stercoralis infection, the researchers began with an immunocompromised strain of mice, and then exposed some to a synthetic steroid called methylprednisolone (MPA) that is commonly used to treat asthma in humans.

The epithelial stem cells, when implanted into immunocompromised mice, regenerated the different cell types of human skin and hair follicles, and even produced structurally recognizable hair shaft, raising the possibility that they may eventually enable hair regeneration in people.

To translate these findings into an in vivo setting, we performed a modification of the established in vivo spheroid - based angiogenesis assay35, by co-grafting HUVEC with WT or Tie2 - silenced BP in a gel matrix subcutaneously into immunocompromised mice.

In contrast, the same cells transplanted to immunocompromised mice remained highly immunogenic; eight of ten are still eliminated when transplanted to wild - type mice (regressor clones).

Using both wild - type and immunocompromised mice, we hope to elucidate the role of dengue - specific CD8 + and CD4 + T - cells against Zika.

When engrafted into immunocompromised mice, human medulloblastoma cells induced expression of HCMV proteins.