Sentences with phrase «of immunological synapse»

The following position is available at the Department Experimental Immunology of the Helmholtz Centre for Infection Research (HZI) in Braunschweig: PhD candidate: Control of immunological synapse formation in regulatory T cells.

Engagement of CD28 outside of the immunological synapse results in up - regulation of IL - 2 mRNA stability but not IL - 2 transcription.

Antigen - specific blocking of immunological synapse formation using bifunctional peptide, Utilization of I - domain of LFA - 1 to Target Drug and Marker Molecules to Leukocytes.

We are using now a genetic yeast two - hybrid screen with this biosensor to identify new proteins that are important for the structure and function of the Immunological Synapse.

Not exact matches

We applied this to systems spanning four orders of magnitude in space and time, including the diffusion of single transcription factor molecules in stem cell spheroids, the dynamic instability of mitotic microtubules, the immunological synapse, neutrophil motility in a 3D matrix, and embryogenesis in Caenorhabditis elegans and Drosophila melanogaster.

Abraham Kupfer describes the three - dimensional structure of supramolecular activation clusters (SMACs), the interface between an antigen presenting cell and a lymphocyte (including key molecules the T cell receptor and the major histocompatibility complex), [i] later coined the immunological synapse and further elucidated by Arash Grakoui, Michael Dustin, Paul Allen, and Andrey Shaw.

These studies led to the discovery of the Immunological - Synapse.

ERM - dependent movement of CD43 defines a novel protein complex distal to the immunological synapse.

A motif in the V3 domain of the kinase PKC -[theta] determines its localization in the immunological synapse and functions in T cells via association with CD28.

Antiparallel segregation of notch components in the immunological synapse directs reciprocal signaling in allogeneic Th: DC conjugates.

A proline - rich motif in the C terminus of Akt contributes to its localization in the immunological synapse.

Peptide - specific intercellular transfer of MHC class II to CD4 + T cells directly from the immunological synapse upon cellular dissociation.

Dynamic recruitment of PAK1 to the immunological synapse is mediated by PIX independently of SLP - 76 and Vav1.