Sentences with phrase «of immunological tolerance»
Richard K. Gershon and K. (Kazunari) Kondo demonstrate a role of T cells, suppressor T cells, in the induction of immunological tolerance.
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Since then he has continued to investigate new strategies to overcome the major hurdles to safe and effective gene transfer, translate then into new therapeutic strategies for genetic disease and cancer, and allowed new insights into hematopoietic stem cell function, induction of immunological tolerance and tumor angiogenesis.
Not exact matches
In the new study, scientists built upon previous discoveries that a safe, non-reproducing vaccine strain of T. gondii could cure mice of several types of solid tumors, and identified which parasite proteins and which immunological pathways are required to break immune tolerance.
An article appearing in the latest edition of the journal Cell discusses how immunological self - tolerance develops.
«If you can prevent antibody formation in the first place, by finding some way of producing immunological tolerance that gets around that type of protocol, that would be a major advantage,» says David Lillicrap, a clinician and researcher who specializes in bleeding disorders at Queen's University in Kingston, Ontario, Canada.
Allergen will be combined with novel immunomodulators — both adjuvants and specific immunological targets implicated in allergic responses — to invoke depletion and deviation mechanisms of tolerance.