Sentences with phrase «of immunosuppressive therapy»
The type, intensity and duration of immunosuppressive therapy contribute to the risk of developing skin cancer, such as melanoma, after transplantation.
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All the monkeys had been put on immunosuppressive therapy to prevent rejection of the transplanted human cells.
All of the patients who were treated had persistent severe or life - threatening symptoms related to myasthenia gravis (MG), although they had used intensive immunosuppressive therapies.
Ildstad and her colleagues report that five of eight people who underwent the treatment were able to stop all immunosuppressive therapy within a year after their kidney and stem - cell transplants, four of which came from unrelated donors.
Even with immunosuppressive therapy, 10 to 15 percent of kidney recipients experience rejection during the first year after transplantation.
After implantation of a foreign tissue a patient must take immunosuppressive drugs and the damage caused by such therapy often outweighs its gains.
Genetically modified «hunter» T cells successfully migrated to and penetrated a deadly type of brain tumor known as glioblastoma (GBM) in a clinical trial of the new therapy, but the cells triggered an immunosuppressive tumor microenvironment and faced a complex mutational landscape that will need to be overcome to better treat this aggressive cancer, Penn Medicine researchers report in a new study this week in Science Translational Medicine.
Researchers found the gene therapy approach had stronger results when used in combination with either depletion of immunosuppressive cells from the tumor mass or with immune checkpoint blockade.
«Further research will reveal whether these antibodies are the mark of a clinically relevant subset of patients and, if so, whether immunosuppressive therapies can effectively treat children with these debilitating illnesses.»
It is approved by the U.S. Food and Drug Administration (FDA) for treating certain types of leukemia and is helpful in other conditions that require immunosuppressive therapy.
The application of calcineurin inhibitors (CNIs) would abrogate the immunosuppressive effect of MSC therapy.
In theory, the developing fetus with an immature immune system should be a prime target for successful transplantation, since the risk of graft rejection is low and the need for long - term immunosuppressive therapy may be avoided.
A treatment plan may include red blood cell transfusions, intravenous immune globulin to strengthen the immune system, an iron - rich diet or iron supplements, exchange transfusions to replace damaged blood with fresh blood, surgery, immunosuppressive therapy, or partial exchange transfusions to slowly remove and replace a large portion of a patients blood volume.
Patient - specific stem cells may offer an alternative to embryonic stem cells that will skirt the need for immunosuppressive therapy as well as the social and political ramifications of embryonic stem cell research, but their utility extends far beyond such groundbreaking advances and will assist future clinical practice and patient care.
Immunosuppressants are introduced into the recipient's body to impede organ rejection, but immunosuppressive therapy can increase the risk of infection and other harmful conditions.
At UIC, Dr. Rondelli has begun to use immunosuppressive therapy in lieu of chemo to increase the odds of survival.
Some of the treatments used for autoimmune disease include corticosteroid treatment and other anti-inflammatory therapies, and immunosuppressive drugs.
As I began immunosuppressive therapy, I was told by specialists that I would not have a normal life: it would be filled with medical treatments, disability, a «high likelihood of early mortality» and «no chance of a normal life.»
Polyarthritis is a group of diseases that are not usually recognized as infectious, but are extremely responsive to immunosuppressive therapies.
Response in some patients to immunosuppressive therapy suggests that many of these dogs have immune mediated disease.
Additionally, to help suppress her immune system from attacking her own cells further, Bella was placed on an immunosuppressive therapy of medications.
She will need to continue immunosuppressive therapy for at least 4 - 6 months to keep her in complete remission of IMHA.
However, immunosuppressive therapy can increase the risk of infections, especially for dogs with megaesophagus who are already prone to developing aspiration pneumonia.
Dogs that have had their spleen removed, and those that are on long - term immunosuppressive steroid drug therapy, can develop especially severe complications from Babesia, irrespective of whether they are infected before, during or after the particular therapy or procedure.
Miticidal therapy is continued 4 weeks beyond obtaining negative results of at least 2 scrapings performed 3 to 4 weeks apart.3, 8 Demodicosis may relapse for several reasons, including exposure to immunosuppressive medications, estrus / parturition, or concurrent diseases.
Management of the disorder may include continuing the medications from treatment in order to protect the remaining stomach lining, and immunosuppressive therapies may be considered to prevent further damage.
Treatment depends on the type and severity of IBD and frequently involves diet changes, vitamin supplementation, antimicrobial or immunosuppressive therapy.
Therapy centers on immunosuppressive doses of steroids and sometimes the use of additional chemotherapeutic agents.
Investigating the Use of Gastroprotectants as a Means of Preventing Iatrogenic Gastrointestinal Signs Associated With Immunosuppressive Corticosteroid Therapy.