Sentences with phrase «of innate immunity»

They therefore provide a simple model for the study of innate immunity to viral infections.

The complement system is an important part of the innate immunity.

«The current study reveals the new roles of innate immunity in ALS pathomechanism and provides a clue to develop a new therapeutic approach for protecting ALS motor neurons.»

Determining the role of innate immunity mediated by antibodies in protection against viral infection.

It is known that macrophages are an important component of the innate immunity against tumors and they are attracted by locally secreted chemokines [4].

Her graduate thesis focused on the genetic regulation of innate immunity in C. elegans.

«This highlights how important introgression events [the movement of genes across species] may have been in the evolution of the innate immunity system in humans.»

She has pioneered new areas of innate immunity, most notably reporting the first study describing the entire human NOD - like receptor family and continued to be a leader in this field.

Her work combines fundamental innate immunology with molecular biology and she has reported extensively on the impact of innate immunity in infection, autoimmunity, cancer, microbiome composition and metabolic disorders.

The basic science of innate immunity and the more translational focus on vaccine development dovetail nicely in his laboratory, tenOever says.

An unexpected finding was that many of the innate immunity pathways that were active in the late stages of these inherited blinding diseases were the same as those that are associated with more common vision disorders including diabetic retinopathy and age - related macular degeneration, or AMD.

Thus, in the absence of innate immunity, the adaptive immune system can compensate so that host and bacterial mutualism can be maintained.

Pinpointing the origins of gamma - ray bursts, determining the workings of innate immunity, and extending the use of differential equations to applications in relativity are achievements paying off in Shaw Prizes for the scientists involved.

Regulatory evolution of innate immunity through co-option of endogenous retroviruses.

Zhijian «James» Chen, Ph.D., has received the 2018 Lurie Prize in Biomedical Sciences for his discovery of the cGAS enzyme, a sensor of innate immunity.

In 1984, he joined the Laboratory of Alberto Mantovani at the «Mario Negri» Institute in Milano, Italy, providing the first descriptions of innate immunity perturbations in AIDS.

The alpha2 beta1 integrin provides a co-stimulatory signal required for mast cell activation, cytokine secretion and initiation of innate immunity.

4/23/2008 Researchers Link Master Regulator of Innate Immunity to the Hypoxic Response Survival of all animals depends on their ability to withstand microbial infections and adapt to fluctuations in oxygen concentrations.

Our current work defines one more component of a specific branch of innate immunity responsible for the recognition and clearance of senescent cells and presumably involved in keeping us young.

History of innate immunity in neurodegenerative disorders.

Case Western Reserve researcher investigates the role of innate immunity CWRU School of Medicine Press Release, April 11, 2018

Long - time readers of this blog will not be surprised to hear that animal research has featured prominently in the work for which this year's winners of the Nobel Prize in Physiology or Medicine are being honoured - Bruce A. Beutler and Jules A. Hoffmann for their for their discoveries concerning the activation of innate immunity, and... Continue reading Nobel Prize 2011: Flies and mice take a bow!

Saturday, Oct. 21, 9:15 - 9:30 a.m., Room 220B, South Building Platform Presentation: Epigenetic modifications of innate immunity genes impact early - stage non-small cell lung cancer survival: An integrative analysis of epigenome and transcriptome in Caucasian population R. Zhang, Harvard T.H. Chan School of Public Health, et al

That's despite the many contributions of the Drosophila model to understanding mammalian biology — like the chromosomal basis of inheritance, genetic linkage, body plan development, the molecular basis of innate immunity, circadian rhythms, and more.

There is also a particular need for replication and extension of our finding that greater protective parenting was associated with a significant shift in cell - type composition in the direction of relatively fewer CD14 monocytes (a marker of innate immunity), suggesting potential long - term impact on chronic inflammation (Irwin and Cole, 2011).

(i) In this context we have demonstrated the angiogenesis - modulatory actions of components of the innate immunity, such as neutrophil - derived alpha - defensins, or the complement system and in particular, the anaphylatoxin C5a receptor.

This talk is titled: «G protein - coupled receptors mediate neural regulation of innate immunity in C. elegans», Friday, April 27, 12:10 p.m.

The current efforts of her laboratory are focused primarily on four areas of innate immunity: the molecular basis of pathogen recognition; innate immunity to malaria; Type I interferon gene regulation; and counter regulation of innate immune recognition.

Our goals include elucidating fundamental events and biologic endpoints surrounding RNase L that impact on viral replication cycles and tumor biology.Another area of research concerns the roles of innate immunity and genetics in prostate cancer.

These three and others are components of innate immunity, the arm of the immune system that responds both to invading pathogens and to the body's own cells when they are damaged or dying, helping clear away debris.

Additional experiments further tested their hypothesis that amyloid - beta is a «foot soldier» of innate immunity, as Moir puts it.

University of Washington Variation and regulation of innate immunity to Mycobacteria

The efficacy of innate immunity targeted therapeutic approaches (like diet) reiterates the continued role of innate immunity in type 1 and type 2 diabetes.