If you want to err on the side of extra caution, don't breed it to another dog with iris hypoplasia nor to dogs with a family history
of iris coloboma.
The parents and full and half siblings of an affected dog should not be bred close on the pedigree that produced it and should be bred to mates that do not have a family history
of iris coloboma.
Not exact matches
Conte et al applied linkage mapping and exome sequencing
of a five - generation British family with dominant retinal degeneration and bilateral
iris coloboma («holes in the
iris»).
A dog could have a
coloboma of the
iris, the optic nerve, the lens, or even an eyelid.
Iris Colobomas (IC) are a cleft in the
iris of the eye and will impair vision if large.
A large
coloboma of the
iris can inhibit its natural contraction in response to bright light, causing the dog to squint the affected eye.
Less frequently seen are progressive rod cone degeneration (a form
of progressive retinal atrophy), collie eye anomaly,
iris coloboma, and persistent pupilary membrane.
The mode
of inheritance for
iris coloboma is unknown.
In many cases the effect on vision is minimal; however a large
coloboma can force a dog to squint in bright light because the
iris is incapable
of contracting to reduce the amount
of light entering the eye.
Other eye diseases include, roughly in order
of frequency, cataract, distichiasis, progressive rod - cone degeneration (a form
of PRA), CEA,
iris coloboma, persistent pupilary membrane, cone degeneration, and canine multifocal retinopathy.
Dogs affected with this condition will exhibit some combination
of the following: Microphthalmia, eccentric pupils,
coloboma or other irregularities
of the
iris, lens luxation, cataract, retinal dysplasia or detachment, persistent pupillary membrane, equatorial staphyloma or lack
of a tapetum.
The most common eye diseases in the breed are cataracts, distichiaisis, persistent pupilary membrane, and
iris coloboma, with Progressive Rod Cone Degeneration (PRCD), a form
of progressive retinal atrophy (PRA), Collie Eye Anomaly (CEA), Canine Multifocal Retinopathy (CMR), and glaucoma have been seen but are rare.
Colobomas may be only small notches out
of the inner edge
of the
iris, pie slices, or massive holes — occasionally so large it appears the dog has no
iris at all.
Multiple
iris colobomas gives his pupil an oval or askew appearance and potentially results in a bit
of vision loss.
A
coloboma is a piece
of missing tissue in the eye, and in the Australian shepherd, it's most likely to manifest in his
iris.
An
iris coloboma is an abnormality in the development
of the
iris that usually presents as a notch or cleft
of the
iris at the edge
of the pupil.
His medical history includes
coloboma of the
iris with almost total vision loss
of the left eye and myopia and astigmatism
of the right eye.