Not exact matches
This clinical study, published in the Proceedings
of the National Academy
of Sciences, tested the possibility
of imaging inflammation in the pancreas
of human volunteers using ferumoxytol, a coated
iron nanoparticle approved by the FDA as an
iron replacement therapy, and MRI.
One species, Magnetospirillum gryphiswaldense, is easily cultivated in the lab — with or without magnetic
nanoparticles in their interior depending on the presence or absence
of iron in the local environment.
The researchers engineered
nanoparticle complexes containing small amounts
of ropivacaine and the
iron oxide mineral magnetite.
One promising idea, known as magnetic hyperthermia, involves injecting minuscule «
nanoparticles,» basically microscopic lumps
of iron oxide or other compounds, into tumors to make them magnetic.
In other words, they could tell the extent to which an individual
nanoparticle of lithium
iron phosphate had reacted.
Heat treatment after an injection
of traditional
iron oxide
nanoparticles had no significant effect on the tumors.
An
iron oxide
nanoparticle applied to teeth prior to treatment with hydrogen peroxide effectively reduced the onset and severity
of cavities (indicated with red arrows) in rats.
HST researchers have experimented with polymer - coated
iron oxide
nanoparticles held together by DNA tethers to help them create a visual image
of a tumor through magnetic resonance imaging.
Instead
of simply applying an antibiotic to the teeth, they took advantage
of the pH - sensitive and enzyme - like properties
of iron - containing
nanoparticles to catalyze the activity
of hydrogen peroxide, a commonly used natural antiseptic.
To create a diabetes vaccine, Santamaria has attached a cocktail
of antigens from pancreatic beta cells to synthetic
iron oxide
nanoparticles.
Yet, to be effective, the size
of the
iron oxide
nanoparticles had to be just right — and had to be maintained in a strong matrix that was both flexible and resilient to deal with large volume changes while optimally conducting electricity.
Gao and Koo reached out to Cormode, who had experience working with
iron oxide
nanoparticles in a radiological imaging context, to help them synthesize, characterize and test the effectiveness
of the
nanoparticles, several forms
of which are already FDA - approved for imaging in humans.
An intensive collaboration between University
of Helsinki, Finland, and Okinawa Institute
of Science and Technology, Japan, showed that in some condition
iron nanoparticles can grow in cubic shape.
A combination
of iron - oxide
nanoparticles and an alternating magnetic field, which together generate heat, have activated an immune system response to tumors in mice according to an accepted manuscript by Dartmouth - Hitchcock Norris Cotton Center researchers in the journal Nanomedicine: Nanotechnology, Biology and Medicine released online on February 24, 2014.
Previous cancer studies had shown that by injecting tumors with magnetic
nanoparticles made
of iron oxide — «essentially rust, with well - tuned magnetic properties,» Anikeeva says — then exposing them to rapidly alternating magnetic fields, excited
nanoparticles can be used to heat and destroy cancer tumors while leaving surrounding, healthy tissue intact.
An endowed professor
of pediatric cardiology at Children's Hospital
of Philadelphia in Pennsylvania, Levy had been working with his team on biodegradable polymer
nanoparticles infused with
iron oxide.
As an alternative, contrast agents based on
iron oxide
nanoparticles are practically unused because
of the difficult readability
of the results.
Researchers at Umeå University, together with researchers at Uppsala University and Stockholm University, show in a new study how nitrogen doped graphene can be rolled into perfect Archimedean nano scrolls by adhering magnetic
iron oxide
nanoparticles on the surface
of the graphene sheets.
HYEON Taeghwan, director
of the Center for
Nanoparticle Research explains: «Let's take the example
of a MRI analysis
of a brain with Alzheimer's:
iron oxide in the blood vessels would appear as black and the amyloid plaques as gray.
In place
of gadolinium - based contrast agents, the researchers have found that they can produce similar MRI contrast with tiny
nanoparticles of iron oxide that have been treated with a zwitterion coating.
It shows that the magnetic interaction between the
iron oxide
nanoparticles is one
of the main effects behind the scroll formation.
Certain strains
of bacteria absorb
iron to make magnetic
nanoparticles that let them navigate using the Earth's magnetic field.
Before injecting nematodes with magnetic
nanoparticles, the scientists first coated the manganese —
iron nanoparticles with polyethylene glycol, a molecule that targeted the particles to the mucus layer
of the amphid region (an opening near the nematode's mouth that hosts the nerve cells involved in the heat avoidance reflex).
When the scientists examined the cells in the growing communities closely, they found
nanoparticles of magnetite on the surface
of cells and, in some cases, grains
of the
iron mineral connecting microbial pairs.
To find tumors via MRI, the Stanford team used a new contrast agent consisting
of nanoparticles of iron.
None
of the patients experienced adverse reactions to the
iron nanoparticles, though the FDA has previously noted a small risk
of allergic reaction to the
nanoparticles» coating.
To get round this, Wilhelm Roell at the University
of Bonn in Germany and his colleagues loaded muscle stem cells with
iron oxide
nanoparticles to make them magnetic.
Nickels M, Xie JP, Cobb J, Gore JC and Pham W. Functionalization
of Iron Oxide
Nanoparticles With a Versatile Epoxy Amine Linker.
A comprehensive analysis
of transfection - assisted delivery
of iron oxide
nanoparticles to dendritic cells.
The team used
iron oxide for the core
of the
nanoparticles, which not only enables the team to use them for magnetic resonance imaging, but opens up possibilities in remote guidance and localized magnetic heating to hasten the breaking up
of the clots.
I've been experimenting with T10 dextran coated
iron oxide
nanoparticles, obviously not the same as fullerenes, but still a very interesting tool, I've been testing if the coating is giving the particle antioxidant abilities because
of it's the (basically) indigestable sugar chains (glucose) creating a high surface area which are largely made from hydroxyl groups, I hypothesised this act's as a «sink» for reactive oxygen species converting them to water.
Identification
of the precise 3 - D coordinates
of iron, shown in red, and platinum atoms in an
iron - platinum
nanoparticle..
The image
of the
iron - platinum
nanoparticle (referenced in the headline) reminds
of foetal ultrasound images.
«This could help scientists learn how to steer the growth
of iron - platinum
nanoparticles so they develop more highly magnetic patterns
of atoms,» says Ercius.
By taking multiple images
of the
iron - platinum
nanoparticle with an advanced electron microscope at Lawrence Berkeley National Laboratory and using powerful reconstruction algorithms developed at UCLA, the researchers determined the precise three - dimensional arrangement
of atoms in the
nanoparticle.
Now, UCLA [University
of California at Los Angeles] physicists and collaborators have mapped the coordinates
of more than 23,000 individual atoms in a tiny
iron - platinum
nanoparticle to reveal the material's defects.
The researchers then used the three - dimensional coordinates
of the atoms as inputs into quantum mechanics calculations to determine the magnetic properties
of the
iron - platinum
nanoparticle.
«Deficient neuron - microglia signaling results in impaired functional brain connectivity and social behavior» Y. Zhan, R.C. Paolicelli, F. Sforazzini, L. Weinhard, G. Bolasco, F. Pagani, A. L. Vyssotski, A. Bifone, A. Gozzi, D. Ragozzino, C.T. Gross Nature Neuroscience 17 (3), 400-4006 (2014) «USPIO - loaded Red Blood Cells as a biomimetic MR contrast agent: a relaxometric study» A. Boni, D. Ceratti, A. Antonelli, C. Sfara, M. Magnani, E. Manuali, S. Salamida, A. Gozzi, and A. Bifone Contrast Media and Molecular Imaging 9, 229 - 236 (2014) «Distributed BOLD and CBV - weighted resting - state networks in the mouse brain» F. Sforazzini, A.J. Schwarz, A. Galbusera, A. Bifone, and A. Gozzi NeuroImage 87, 403 - 415 (2014) «Antimicrobial peptides design by evolutionary multiobject optimization» G. Maccari, M. Di Luca, R. Nifosì, F. Caldarelli, G. Signore, C. Boccardi, and A. Bifone PloS Computational Biology 9 (9): e1003212 (2013) «Differential effect
of orexin - 1 and crf - 1 antagonism on stress circuits: a fMRI study in the rat with the pharmacological stressor yohimbine» A. Gozzi, S: Lepore, E: Merlo Pich, and A. Bifone Neuropsychopharmacology 38 (11): 2120 - 2130 (2013) «Water dispersal and functionalization
of hydrophobic
iron oxide
nanoparticles with lipid - modified poly (amidoamine) dendrimers» A. Boni, L. Albertazzi, C. Innocenti, M. Gemmi, and A. Bifone.
A 2017 study co-authored by John Bischof, professor
of mechanical engineering at the University
of Minnesota, and published in Science Translational Medicine, used specially coated
iron oxide
nanoparticles.
They have been working on using
iron nanoparticles doped with Pd, Ni or Cu to perform catalytic reactions such as Suzuki - Miyaura cross couplings, Sonagashira coupling, and reduction
of nitro - containing aromatics.
Napier's presentation, titled «Superparamagnetic
Iron Oxide
Nanoparticles for Delivery
of DNA - based Contraceptive Vaccines for Feral Cats,» dealt with a portion
of Napier's research in developing and delivering contraceptives to feral cats.