Background — The purpose of this study was to assess the relation of adverse childhood experiences (ACEs), including abuse, neglect, and household dysfunction, to the risk
of ischemic heart disease (IHD) and to examine the mediating impact on this relation of both traditional IHD risk factors and psychological factors that are associated with ACEs.
Prevalence and Adjusted Odds Ratios for Traditional and Psychological Risk Factors
of Ischemic Heart Disease
In brief, intake of high fiber foods has been independently associated with reduced incidence
of ischemic heart disease and stroke (Humble et al., 1993; Khaw and Barrett - Connor, 1987; Pietinen et al., 1996; Rimm et al., 1996; Wolk et al., 1999).
Whole - grain intake may reduce the risk
of ischemic heart disease death in postmenopausal women: The Iowa Womenâ $ ™ s Health Study.
The epidemiology of whole grains and several chronic diseases began unfolding in the mid-1990s with reviews of cancer case - control studies plus one prospective study
of ischemic heart disease incidence (9 — 11).
1,300 autopsied over five years in a Bantu hospital, and less than ten cases
of ischemic heart disease, our # 1 killer.
According to research found in Atherosclerosis, Thrombosis, and Vascular Biology, large LDL particles were not found to be associated with an increased risk
of ischemic heart disease in men, and that the cardiovascular risk LDL cholesterol does pose is related to levels of its small particles.
Out of Harvard recently: «Dietary protein and risk
of ischemic heart disease in middle - aged men.»
Cerebrovascular disease mostly impacts the elderly or those individuals have a history
of ischemic heart disease or diabetes.
«We found there was a surprisingly strong association between levels of health anxiety and the risk
of ischemic heart disease,» Berge says.
Even when the researchers controlled for established cardiovascular disease risk factors, they found about a 70 % increased risk
of ischemic heart disease in the years of followup.
Clinical observation on the treatment
of ischemic heart disease with Astragalus membranaceus 4.
Another example is AMDC — autologous adult skeletal muscle primary cells that are expanded in culture prior to injection and are tested for the treatment
of ischemic heart failure.
Dr. Anne, together with first author Harriet Eldredge - Hindy, M.D., showed that this same cohort of patients will likely have a reduced risk
of ischemic heart disease after 10 years.
The researchers identified a cohort of 7,704 RA patients from the Swedish Biologics Register with no previous incidence
of ischemic heart disease who started their first TNF inhibitor between 2001 and 2010.
The study showed that patients who held their breath during radiation therapy had only a 1.4 percent rate
of ischemic heart disease after 8 years of follow up and an estimated rate of 3.6 percent after 10 years.
As pharmacologists, our interest is primarily in the mechanisms and therapeutics
of ischemic heart diseases, and we have been working on the cardiovascular effects of herbs according to modern scientific criteria.
Not exact matches
Some autopsy data shows that infants
of smokers have signs
of established hypoxic -
ischemic cellular injury in the brain and the
heart which probably occurred in antenatal life, may have been caused by suboptimal placental function and may have been sub-clinical, but if the baby continues to be in a vulnerable environment exposed to post-natal passive smoking, this could affect autonomic nervous system function and lead to poor temperature control, and poor
heart rate and respiration control.
Through shortened patient examination times, higher patient throughput, and lower cost per MRI examination, EPI may become a powerful tool for early diagnosis
of some common and potentially treatable diseases such as
ischemic heart disease, stroke, and cancer.
«GRK2 inhibitors may have very real therapeutic benefits, especially in the context
of heart failure and
ischemic heart disease,» Stamler said.
James Mitchell, who studies stress resistance at the Harvard School
of Public Health in Boston, was especially interested in
ischemic reperfusion injury, a problem that often occurs with
heart attacks and strokes, and sometimes even from
heart and vascular surgery.
They found the CD4 + T - cells were globally expanded and activated during chronic
ischemic heart failure, and that there was an expansion
of memory T - cells in the spleen.
Ischemic heart disease, stroke, low back and neck pain, road injuries, and COPD have also caused an increasing amount
of health loss since 1990.
The physical mechanism
of platelet - driven clot contraction they observed is already informing new ways to think about diagnosing and treating conditions such as
ischemic stroke, deep vein thrombosis, and
heart attacks.
Frits R. Rosendaal, M.D., Ph.D.,
of Leiden University Medical Center, the Netherlands, and coauthors determined long - term mortality and morbidity in young women who survived myocardial infarction (
heart attack) or
ischemic stroke compared with a control group.
The study included 226 women who had a
heart attack (average age 42), 160 women who had
ischemic stroke (average age 40) and 782 women (average age 48) in the comparison group with no history
of arterial thrombosis (blood clot in an artery).
The study, published today in Circulation: Cardiovascular Quality and Outcomes, examined the records
of more than 38,000 people with chronic
ischemic heart disease living in either urban or rural areas.
The Cardiothoracic Surgical Trials Network (CTSN) is reporting results for the first time from a clinical trial
of patients who have a complication
of coronary
heart disease known as moderate
ischemic mitral regurgitation (IMR).
Dr Andersen said the study was important because, although there have been other studies looking at the effects
of endurance exercise on various cardiovascular problems such as
ischemic heart disease and stroke, there have been only a few, smaller studies
of its effect on
heart rhythm disturbances, and they have tended to look at people who are less physically active, or compared very sedentary people with those who were very active.
This study was presented at the Featured Clinical Research Session I: Two - year Outcomes
of Surgical Treatment
of Moderate
Ischemic Mitral Regurgitation: A Randomized Clinical Trial from The Cardiothoracic Surgical Trials Network The Moderate
Ischemic Mitral Regurgitation trial was supported by a cooperative agreement (U01 HL088942) funded by the National
Heart Lung and Blood Institute, the National Institutes
of Neurological Disorders and Stroke
of the National Institutes
of Health (NIH), Bethesda, MD, and the Canadian Institutes
of Health Research.
Earlier studies in STEMI patients showed that
ischemic postconditioning improved ST - segment resolution — an important marker
of arterial blockage on electrocardiogram — reduced damage to
heart muscle, and in some patients limited the extent
of reperfusion injury.
The top causes
of death worldwide,
ischemic heart diseases and stroke, together with another major source
of illness, that is cancer, require proper imaging
of blood vessels.
A large randomized controlled trial
of ischemic postconditioning in patients who had experienced the deadliest form
of heart attack — ST - segment elevation myocardial infarction (STEMI)-- failed to show that this procedure significantly reduces death from any cause or hospitalization for
heart failure, according to research presented at the American College
of Cardiology's 65th Annual Scientific Session.
Ischemic postconditioning is a variation on angioplasty that involves using 30 - second bursts
of blood flow interspersed with 30 - second pauses to restore blood flow to the
heart.
Women who have gestational diabetes mellitus (GDM) during pregnancy have a higher than usual risk
of developing type 2 diabetes, hypertension, and
ischemic heart disease in the future, according to new research led by the University
of Birmingham.
Data from 3,904 patients who sustained myocardial injury after non-cardiac surgery suggested that
ischemic injury (i.e., an injury caused by a lack
of oxygen) to
heart tissue after non-cardiac surgery explained 24 percent
of deaths in the first 30 days after surgery.
The current study found that mice meant to serve as a model
of ischemic human
heart failure (weaker blood flow after a
heart attack) had higher levels
of activated, pro-inflammatory macrophages, monocytes, dendritic cells and T cells trafficking between their
hearts and spleens than did control mice with healthy
hearts.
Dr. Srivastava has co-founded a biotechnology company to help find new cures for many human diseases and one
of the developmental genes whose role he discovered, Thymosin β4, is currently in clinical trials for patients suffering
ischemic damage to the
heart.
He found 10 percent
of the African - American patients suffered from atherosclerotic cardiovascular disease — defined as a
heart attack,
ischemic heart disease, angina, coronary artery disease or atherosclerotic disease
of any artery.
Dr. Semenza's research interests include the molecular mechanisms
of oxygen homeostasis; gene and stem cell therapy for
ischemic cardiovascular disease; the role
of HIF - 1 in cancer; and protection
of the
heart against ischemia - reperfusion injury.
He studies the processes that regulate blood vessel function and response to injury, with emphasis on the role
of lipid - lowering medications in preventing
ischemic stroke, coronary artery disease, and
heart failure.
Although medical and surgical treatments available today for the
ischemic heart disease patients diminish the risk
of acute myocardial infarction and reduce to some extent the incidence
of recurrent
heart attack, one
of the unsolved challenges is to affect myocardium remodeling occurring during
ischemic heart failure.
HIF - 1 also is required for
ischemic preconditioning, short episodes
of ischemia and reperfusion that protect the
heart against a subsequent prolonged
ischemic insult.
The major outcome
of ischemic damage is aggravation
of the
heart muscle function, known as cardiomyopathy.
Okyanos cardiac cell therapy targets the restoration
of blood flow to the
heart and repairs damaged
heart tissue caused by
heart attack or
ischemic and non-
ischemic heart disease.
During the years 1970 — 1973, all 50 - y - old men living in the municipality
of Uppsala, Sweden, were invited to participate in a prospective survey regarding risk factors for
ischemic heart disease.
Mesenchymal stem cell (MSC)- derived exosomes mediate tissue regeneration in a variety
of diseases including
ischemic heart injury, liver fibrosis, and cerebrovascular disease.
These findings show that smoking, while not affecting the PM - associated risk from
ischemic heart disease, appeared to interact with air pollution to increase the risk
of death from other circulatory diseases.
Research shows the decrease in hormones that comes with early menopause also increases your risk
of premature death, neurological diseases, psychosexual dysfunction, mood disorders, osteoporosis,
ischemic heart disease, and infertility.
Another study examined caffeine's impact on
ischemic muscle contraction pain, which is a specific and intense type
of pain related to
heart attacks.