Sentences with phrase «of isoprenoids»

«We think that understanding the role of isoprenoids during gametocytogenesis and identifying metabolic steps absent or sufficiently different from its human host will allow us to design more efficient drugs to block malaria transmission, which is one of the key components for malaria elimination and eradication,» Cassera said.

So far, our structures span protein families such as cyclophilins, kinases and proteases as well as pathways for biosynthesis, salvage and metabolism of isoprenoids, fatty acids, phospholipids, pyrimidines, purines and polyamines.

This tumor - targeted action of isoprenoids was manifested in animal studies showing no toxicity of isoprenoids at tumor - suppressive doses (reviewed by Mo & Elson, Exp Biol Med, 2004, 229:567 - 85).

Previous work also suggested synergistic impact of isoprenoids on tumor growth, a finding remaining to be confirmed in prostate cancer.

Chs3 recruits Chs4 to Ste24, which cleaves off the aaX peptide allowing carboxy - methylation of the isoprenoid cysteine by Ste14.

Not exact matches

Isoprenoid - mediated suppression of HMG CoA reductase in tumors was previously correlated to growth arrest; the latter was attenuated by supplemental mevalonate.

Considering the medical and cosmetic sector, a great number of researches focused on the isolation of tyrosinase inhibitors from both terrestrial and marine environment belonging to diverse chemical classes such as phenolics (flavonoids, lignans, stilbenes, coumarins, arylbenzofurans, tannins), megastigmane - type (nor - isoprenoid), terpenes, cyclic peptides, alkaloids and steroids.

What's more, by swapping a couple genes, these bacteria can potentially produce any of the so - called isoprenoids, a large and diverse class of natural compounds.

I became acquainted with a group of natural products called isoprenoids.

Specifically, she wants to understand the role that specific metabolites called isoprenoids play in the early stages of development.

Integrated analysis of isopentenyl pyrophosphate (IPP) toxicity in isoprenoid - producing Escherichia coli.

Such records may be obtained using a quite recently developed biomarker approach that is based on the determination of a highly branched isoprenoid (HBI) with 25 carbons (C25 HBI monoene) 29.

Smik, L., Cabedo - Sanz & Belt, S. T. Semi-quantitative estimates of paleo Arctic sea ice concentration based on source - specific highly branched isoprenoid alkenes: a further development of the PIP25 index.