Sentences with phrase «of kappa»

Further, research from our clinic has demonstrated excellent reliability for the ADIS with interrater agreement of kappa = 1.00 for an overall anxiety disorder diagnosis, and between Kappa =.80 and.93 for specific anxiety diagnoses (Lyneham et al. 2007).

Results: For each subscale and factor, the values of kappa for inter-rater reliability were between.625 and.884 (p <.05); the values of retest reliability were between.537 and.832 (p <.05); The scores of the subscale of PSDQ were correlated with each factor significantly (coefficient of correlation:.732 -.951, p <.05), and the correlation coefficient was more than those between each factor of this subscale (correlation coefficient:.382 -.834, p <.05).

Legend has it that a piece of kappa cloth was thrown into the pool of a nearby waterfall and a rainbow met it.

Inhibition of kappa - casein glycomacropeptide and lactoferrin of influenza virus hemagglutination.

Within this context, there are two primary lines of research in the lab, sex differences in addiction and the role of kappa - opioid receptors in cocaine withdrawal.

Sex differences in sensitivity to the depressive - like effects of the kappa opioid receptor agonist U-50488 in rats.

They have demonstrated that female rats are less sensitive than males to the depressive - like effects of kappa - opioid receptor activation.

This has important ramifications for the neural mechanisms underlying mood and affect as well as for the contribution of kappa receptors to addictive behavior in men versus women.

Ablation of kappa - opioid receptors from brain dopamine neurons has anxiolytic - like effects and enhances cocaine - induced plasticity.

Blockade of kappa - opioid receptors attenuates the development of depressive - like behaviors induced by cocaine withdrawal in rats.

DNA elements are asymmetrically joined during the site - specific recombination of kappa immunoglobulin genes

Not exact matches

Does a decline in the number of Phi Beta Kappas going into the ministry reflect a decline in quality?

In animal studies, activation of nuclear factor - kappa B (NF - kB); activation of inducible nitric oxide synthase (iNOS), and cyclooxygenase - 2 (COX - 2); and formation of malondialdehyde (MDA) have all be shown to get reduced following consumption of either sweet potato or its color - containing extracts.

To me it looks like a Warrington wolves rlfc kit i do nt like kappa at all to much branding all over the shirt as well as it looks like a rugby shirt but it is one of the best leeds away kits in years.

Most of the commonly occurring cancers, notably breast, prostate, and lung cancer, spread (metastasize) to bone; I was set to the task of studying the role of a transcription factor (gene - expression regulator), NF B (nuclear factor kappa B), in cancer metastasis.

«These effects were reduced, however, in terms of both intensity and duration, if the mice had been treated with a kappa - opioid receptor antagonist, a drug that blocks the activity of one of the brain's own opioid systems.»

Since genes for the T - cell receptor beta chain were previously shown to be on mouse chromosome 6, all three of the Ig - like multigene families expressed and rearranged in T cells are located on different chromosomes, just as are the B - cell multigene families for the Ig heavy chain, and the Ig kappa and lambda light chains.

Bohn noted isoquinolinone 2.1 is one example of a new class of «biased» kappa agonists that avoid many central nervous system side effects by preferentially activating a G protein - mediated signaling cascade without involving another system based on β - arrestin protein interactions.

For example, nuclear factor - kappa B (NF - kB) is a complex of proteins that acts as a master switch for turning inflammation genes on and for controlling cell death.

Working with cultures of respiratory tract cells, Elias's team found that the gene that codes for il - 6 is inactive unless a protein known as nf - kb (nuclear factor - kappa beta) attaches to the gene.

Not only did the CLA's impact on NF - kappa - B activity reduce the production of the COX - 2 enzyme, but it also dampened the activity of any COX - 2 that was made.

They found that it modulated the activity of a molecule, NF - kappa - B, that controls parts of the immune response.

The sequence of the complementary DNA encoding pp40 revealed similarity to the gene encoding MAD - 3, a protein with mammalian I kappa B - like activity.

Their new approach also reduces the potential for drug abuse and avoids the most common side effects — sedation and anxiety — of drugs designed to target the nervous system's kappa opioid receptors (KORs).

University of North Carolina researchers uncovered a cellular mechanism by which kappa opioid receptors (KOR) drive anxiety.

Using X-ray crystallography and computer modelling, Daniel Wacker at the University of North Carolina and his colleagues have designed a new opioid molecule that binds tightly and exclusively to kappa receptors, potentially minimising the likelihood of addiction or side effects.

As a monomer, GR represses the activities of pro-inflammatory transcription factors, such as activator protein 1 or nuclear factor kappa B (NF - kB) by a tethering mechanism called transrepression.

Dr. Carlezon and his group were the first to report that a class of drugs called kappa - opioid receptor (KOR) antagonists has antidepressant, anti-anxiety, and anti-stress effects in their behavioral tests.

Those naturally produced opioids, and the opioid drugs that imitate them, inhibit pain by acting on three kinds of opioid receptors — mu, kappa and delta — that are found on the outside of nerve cells in the brain, spinal cord, digestive tract and elsewhere.

Nuclear factor kappa B in the dorsal raphe of macaques: an anatomical link for steroids, cytokines and serotonin.

Nuclear factor kappa - B mediates selective induction of neuronal nitric oxide synthase in astrocytes during low - level inflammatory stimulation with MPTP.

Inhibits the activity of dimeric NF - kappa - B / REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals.

Hepatitis C Virus Regulates Transforming Growth Factor [beta] 1 Production Through the Generation of Reactive Oxygen Species in a Nuclear Factor [kappa] B - Dependent Manner.

Control of the senescence - associated secretory phenotype by NF --LCB- kappa -RCB- B promotes senescence and enhances chemosensitivity.

Finally the team is active in a number of collaborative projects with other synchrotrons in Europe, such as EDNA and the kappa working group.

In CLL and other B - cell malignancies researchers have previously observed that deregulation of the NF kappa B (NF - kB) signalling pathway appears to be particularly important.

Li, Y.; Reddy, M. A.; Miao, F.; Shanmugam, N.; Yee, J. - K.; Hawkins, D.; Ren, B.; Natarajan, R. Role of the Histone H3 Lysine 4 Methyltransferase, SET7 / 9, in the Regulation of NF --LCB- kappa -RCB- B - dependent Inflammatory Genes: RELEVANCE TO DIABETES AND INFLAMMATION.

Proinflammatory cytokines enhance estrogen - dependent expression of the multidrug transporter gene ABCG2 through estrogen receptor and NF -LCB- kappa -RCB- B cooperativity at adjacent response elements.

Through computer analysis they were able to modify the chemical makeup of the compounds and find the precise formulation for creating the strongest bond between the compound and the kappa opioid receptor without affecting any other receptors in the cell.

We do however detect a significantly larger excess on three of these follow - up targets: Altair, $ \ upsilon $ And and $ \ kappa $ CrB.

This annotation was used to query 107 whole genome sequences from 19 breeds and identified over 5500 alleles across the 550 genes of the seven AR loci: the IG heavy, kappa, and lambda loci; and the TR alpha, beta, gamma, and delta loci.

Analysis of Genes Induced by Sendai Virus Infection of Mutant Cell Lines Reveals Essential Roles of Interferon Regulatory Factor 3, NF --LCB- kappa -RCB- B, and Interferon but Not Toll - Like Receptor 3

In separate experiments, an adenoviral construct inhibiting IKKβ, an upstream component of the nuclear factor kappa - b (NFkB) pathway, was a priori injected into the NAc.

All types of mammal milk, including cow's milk and human milk, also contain another type of casein called kappa casein, but kappa casein comes in two very different forms — a «ruminant» form (for animals with more than one stomach, like cows) and a «non-ruminant» form (for animals with only one stomach, like humans).

It works by activating the inflammatory nuclear factor kappa B (NF - kB for short), which binds to your DNA and triggers a number of inflammatory cascades throughout the body.

How sensitive one is to the thermal nature of foods depend on one's constitution (vata, pita, kappa) My personal experience is that there's a lot of truth to this.

Maines MD, Kappas A. Regulation of cytochrome P -450-dependent microsomal drug - metabolizing enzymes by nickel, cobalt, and iron.

Wang D, Sun X, Sadee W. Different effects of antagonists on mu -, delta -, and kappa - opioid receptors with and without agonist pretreatment.

Researchers have found that they help turn off NF - kappa B, a protein that regulates the immune system and triggers the process of inflammation.

According to the Journal of Biological Chemistry, «Curcumin has been shown to block many reactions in which NF - kappa B plays a major role.