Dom is a pioneering developer
of ketone esters and ketone salts.
Administration
of ketone esters in animals have shown anticancer effects, independent of glucose levels (24).
One study of 39 high - performance athletes found that drinking 260 mg
of ketone esters per pound of body weight (573 mg / kg) during exercise improved athletic performance.
Additionally, most of the studies examined the benefits
of ketone esters, not the ketone salts that are found in supplements, like Keto OS, available to consumers.
One study of 15 people found that those who consumed 0.86 calories
of ketone esters per pound (1.9 calories / kg) of body weight had significantly less hunger and desire to eat, compared to those who consumed a carbohydrate drink.
Likewise, the use
of ketone esters and salts, could appear promising to help those that may struggle with the practical applications of the diet.
Researchers at the University of British Columbia and University of Oxford have demonstrated that a single drink
of ketone ester enables better control of blood sugar by reducing spikes in sugar levels.
«Further research into the potential benefits
of ketone ester for human health is vital, and only just beginning.»
Another specific area of interest is the use
of ketone ester supplementation.
Not exact matches
Ketone esters are small organic chemicals that provide energy for the heart, brain and skeletal muscle in a highly efficient way, but are typically produced by the body only during periods
of food scarcity and are not naturally present in typical modern diets.
Our hope, however, is that
ketone ester supplementation will also hold benefits for people who are suffering from debilitating metabolic and neurological diseases by improving energy availability,» said Andrew J. Murray, Ph.D., a researcher involved in the work from the Department
of Physiology, Development and Neuroscience at the University
of Cambridge, in Cambridge, England.
A lab based in Oxford, England has carried out a series
of studies in high - performing athletes utilising
ketone esters.
In this patient, after 6 - 8 weeks
of ingesting a
ketone ester, there were marked improvements in activities
of daily living.
One study has looked at the specific effects
of administering a
ketone ester drink on appetite (14).
In comparison to a sugar based solution, those who consumed the
ketone ester had significantly lower levels
of hunger stimulating hormones.
One study gave eight athletes a novel oral
ketone ester drink every 60 minutes during the initial 5 hour
of recovery, following a glycogen depleting maximal exercise bout (10).
It should be noted that most
of the evidence we have in athletes, have been done with
ketone esters and not salts (as noted earlier the only commercially available exogenous
ketone supplements).
That we wear loin cloths and shun modern medicine (I only do one
of those), eat so low - carb all the time that running our urine through a coffee filter produces valuable
ketone esters (stay tuned for the supplement!)
With just that small change — adding coconut oil to a high - carbohydrate diet - she noticed enough
of an improvement to continue, increase the dose over time, and eventually progress to using a
ketone ester, still in the context
of a relatively high - carb diet.
However, it's important to note that
ketone salts, which are the kind
of ketones found in Keto OS, are much less effective at raising
ketone levels than
ketone esters.
In several studies, supplementing with
ketone salts resulted in beta - hydroxybutyrate levels
of less than 1 mmol / L, while taking
ketone esters raised blood beta - hydroxybutyrate concentrations to 3 to 5 mmol / L (26, 27, 28).
Recently, we have seen an influx
of ketone body supplements (like
ketone salts and
esters) on the market, which may be used to rapidly increase
ketone body availability (without the need to first adapt to a ketogenic diet).