Sentences with phrase «of kidney tissues»

A low urine concentration may indicate that at least two - thirds of the kidney tissues are damaged.

We're hopeful that this finding will pave the way for the future creation of kidney tissues that could function in a patient and eliminate the need for transplantation from a donor.»

Currently, the only definitive way to distinguish rejection from other causes of kidney injury is by performing a biopsy, in which doctors remove a small piece of kidney tissue to look for rejection - associated damage.

Reduced blood flow through the kidneys leads to death of kidney tissue.

It is interesting that we have an excess of kidney tissue in our body.

When 66 % of the kidney tissue is functionally gone, the remaining kidney tissue can not conserve water.

In fact, you have to get down to the point where 2/3 (66 %) of the kidney tissue is non-functional before you get any symptoms at all!

As much as 75 % of the kidney tissue may be destroyed by that time.

The kidneys have a very large reserve capacity, and symptoms of failure are not seen until approximately 75 % of kidney tissue is nonfunctional.

Not exact matches

Generally speaking, the American public is well accustomed to the concept of tissue and organ transplantation, as stories of life - saving heart and kidney transplants, or American Red Cross blood drives collecting blood and platelets for transfusions have become commonplace.

Unfortunately, like most water - soluble vitamins, Vitamin B12 is stored in the liver, kidneys & other tissues & a deficiency may not show up for several years, which is a huge concern because after about 7 years of B12 deficiency there can be irreversible brain damage.

By 40 weeks, a baby's lungs are matured, the kidney and other vital organs are doing their thing, the brain has grown enough soft tissue that will set it up for the rest of life, and the neurological instincts that tell the baby to suck and swallow are kicked into gear.

I was one of those FTMs who experienced pain upon latching at a level 6 - 7 (and I've experienced 5 kidney stones so I have experience gauging pain) and was told it was simply «soreness» when in actuality it was tissue damage.

One person who donates organs (hearts, lungs, liver, kidneys, pancreas and intestines) can save up to eight lives, while a tissue or eye donor (corneas, bone, skin, heart valves, tendons, veins, etc.) can improve more tha 75 lives by restoring eyesight, helping fight infections in burn patients and preventing the loss of mobility and disability.

We showed that a one - time dose of the drug mirabegron stimulates human brown adipose tissue so that it consumes glucose and burns calories,» said lead author Dr. Aaron Cypess, who conducted the work at Joslin Diabetes Center and Beth Israel Deaconess Medical Center, affiliates of Harvard Medical School, and is now at the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health.

Beasley said that various species of trematodes penetrate tadpoles, sometimes killing them and at other times weakening them with tissue damage, kidney failure, or severe limb deformities when the tadpoles develop into frogs.

Such antibodies, when attached to DNA in complexes, get lodged in the walls of arteries and in tissues to cause inflammation that damages blood vessels, skin, joints and the kidneys as part of the most severe type of lupus, systemic lupus erythematosus (SLE).

The researchers examined an equal number of samples (72) of normal kidney and kidney cancer tissues.

Moreover, use of the gel led to significantly lower levels of cisplatin in liver tissue 5 centimetres away from the cancer, and in the kidneys.

Tissues outside of the bones don't naturally calcify, yet mineralization of organs, including the heart, blood vessels, and kidneys, occurs with age and is exacerbated in people with diabetes or kidney disease.

After giving the cells a week to get used to each other, the scientists implanted the chimeric concoction into the protective tissue surrounding the kidneys of living mice.

But it became increasingly difficult to maintain the balance of minerals and fluids in her body, and the generalized swelling of her tissues progressed as her kidneys began to fail.

Standing and staring at the line running along the stone, he knew he could part the delicate, dark - red tissue of the kidney along the avascular plane, across the organ's whole length, causing little blood loss or damage, and pop a kind of cartridge into this incision — a wafer of healthy kidney tissue.

Lead author Christina von Roemeling, a graduate student at Mayo Clinic in Florida, used genomic profiling of nearly 100 kidney cancer patient samples to identify genes that were either over-expressed or under - expressed as compared to patient matched normal kidney tissue samples.

Insert a section of that new kidney tissue, equal in weight to maybe 20 percent of the existing organ.

Greg Fahy of the American Red Cross in Bethesda, Maryland, said last week that he and his colleagues hope to have developed a method for preserving rabbit kidneys — which are very similar in tissue type and structure to human ones — by Christmas.

The researchers say their findings also shed new light on how kidney disease leads to an abnormal thickening of heart muscle tissue called hypertrophy, which is a leading cause of death in people with kidney disease caused by high blood pressure, diabetes, and other illnesses.

Early tests have been promising: The foam completely blocked the arteries of rabbits» kidneys without moving into tissue where it didn't belong.

«Virtual tissue technology reveals new drug target in polycystic kidney disease: Advanced computer simulations show that failures of cell adhesion and inhibition cause two types of kidney cyst formation.»

Lupus is an autoimmune disorder characterized by periodic inflammation of joints, connective tissues and organs including heart, lungs, kidneys and brain.

Ribeiro's team is now investigating the molecular composition of the fat around the kidneys, particularly tissue in close contact with tumours.

These included wakeup glucose levels; levels of the essential minerals calcium, iron, and magnesium; fat and cholesterol levels; kidney and liver enzymes; and several markers for inflammation and tissue damage.

Gorelick would also like to make sure that no dangerous levels of radiation are released as the bacteria die, noting that some buildup was seen in the kidney tissue of the mice treated in the new study.

A September 2002 follow - up study found no evidence for widespread transdifferentiation of blood - forming stem cells in brain, liver, kidney, gut and other tissues.

They also hope to use what they learn from simple models of different tissue types to ultimately build functional human tissues like lung and kidney and neural circuits using larger - scale techniques.

We can see the spinal cord protected by a vertebra, the kidneys, the aorta, sections through various parts of the winding intestines, as well as the muscles, fat and connective tissue that holds it all together.

So we tested this in mouse models and in human polycystic kidney tissues, and, in both cases, high levels of pIgR were expressed in kidney cysts.»

Contrast agents, injected into the patient during an MRI procedure and designed to be quickly cleared from the body by the kidneys afterwards, are needed to make fine details of organ structures, blood vessels, and other specific tissues clearly visible in the images.

If large numbers of white blood cells get into the lungs or kidneys, or into transplanted organs, they can cause damage to healthy tissue.

Additionally, the original kidney tissue was not connected to any blood vessels, even though the primary function of the organ is to filter waste products and excess fluid from the blood.

Transplant recipients who receive a kidney, heart, or lung often develop an immune response to the foreign tissue in the form of antibodies referred as donor - specific HLA antibodies.

Through studies conducted in mice, Oliver M. Steinmetz, MD (University Hospital Hamburg Eppendorf, in Germany) and his colleagues have shown that the messenger protein IL - 6, which is rapidly produced at high levels during an acute inflammatory form of kidney disease, potently dampens activation of tissue - destructive immune cells called macrophages.

«Our stem cells also survive outside of mice, in a culture, so we can also manipulate them in a laboratory,» said Abad, adding that: «The next step is studying if these new stem cells are capable of efficiently generating different tissues such as that of the pancreas, liver or kidney.»

Because donated immune cells recognise the foreign tissue from the transplanted kidney, the thymus gets rid of the recipient's own T - cells that could otherwise attack the kidney.

Furthermore, resolvin D - 1 reduced levels in kidney tissue of the proinflammatory cytokine mRNAs for Il - 6, Il -1-beta, Tnf - alpha and Tgf - beta, and it increased the levels for the reparative cytokines Mrc - 1 and Ym - 1.

This new approach offers a safer alternative to metal complexes, such as gadolinium that are commonly used to enhance MRI images but can have side effects in kidney patients and may build - up in the tissues of individuals needing multiple MRIs.

This is a problem, says Frangioni, because when fluorescent molecules are injected into the blood, only a small fraction is taken up by the tissue of interest; the rest continue to circulate through the blood until filtered either by the kidneys or liver and excreted from the body.

The disorder has an estimated prevalence of 1 in 70,000 births and can affect the liver, heart, kidneys, blood vessels and other tissues of the body.

Growing a replacement version of a thick chunk of tissue like a heart or a kidney requires engineering a network of connected channels into the tissue to act as blood vessels.

Harvard Stem Cell Institute scientists at Brigham and Women's Hospital have found the cellular origin of the tissue scarring caused by organ damage associated with diabetes, lung disease, high blood pressure, kidney disease, and other conditions.