The issue
of kidney toxicity would also be bypassed in cancer patients because the course of treatment is much shorter, measured in weeks to months compared to years of treatment for diabetes patients.
Not exact matches
In a study titled Repeatedly heated palm kernel oil induces hyperlipidemia, atherogenic indices and hepatorenal
toxicity in rats: Beneficial role
of virgin coconut oil supplementation researchers from Ebonyi State University in Nigeria found that virgin coconut oil supplementation had a positive effect on the
kidneys and livers
of rats who were also fed repeatedly heated palm kernel oil.
In January, a study by European researchers tied genetically modified corn created by Monsanto to
toxicity in the
kidney and liver, resulting in hyperbolic headlines about the danger
of GM foods.
His group assessed the animals for changes in body weight as well as potential
toxicity to the liver,
kidney, and blood cells — none
of which was observed.
Administering a combination
of Abraxane ® and Intralipid ® results in less
of toxicity of the chemotherapy drug in the
kidney (bottom row) than administering Abraxane ® alone (top row).
Potential adverse side effects include
toxicity of the nervous system,
kidney and liver, headaches, and rare, but serious skin conditions such as Stevens Johnson syndrome and toxic epidermal necrolysis.
Researchers modeled
kidney development and injury in
kidney organoids (shown here), demonstrating that the organoid culture system can be used to study mechanisms
of human
kidney development and
toxicity.
Patients were also given an infusion
of amino acids as a protective measure against
kidney toxicity.
Similar results were obtained when the
toxicity of niclosamide and oxyclozanide were evaluated against HEK293 human embryonic
kidney cells [35, 36].
«The development
of a functional human
kidney glomerulus chip opens up an entirely new experimental path to investigate
kidney biology, carry out highly personalized modeling
of kidney diseases and drug
toxicities, and the stem cell - derived
kidney podocytes we developed could even offer a new injectable cell therapy approach for regenerative medicine in patients with life - threatening glomerulopathies in the future,» said Ingber.
Kidney toxicity is one
of the most frequent adverse events reported during drug development.
Studies investigating the
toxicity of DEHP have shown it affects two organs in particular: the testicles and
kidneys.
But higher doses
of propylene glycol can acidify the blood, injure the
kidneys, and cause
toxicity.
Second, Warfarin, a vitamin K inhibitor, produces a
toxicity profile almost identical to that
of vitamin D, but does not increase serum calcium levels.81 Third, one group used vitamin D to produce calcium deposition in the
kidneys of chickens at doses that did not lead to hypercalcemia.104 This finding is consistent with a case report
of four post-menopausal women who were taking undetermined doses
of vitamin D without their knowledge in the form
of supplements that appeared to be contaminated with large amounts
of vitamin D2: these patients had abnormally high vitamin D levels, three times the calcium in their urine as is normal, and appeared, albeit inconclusively, to have associated bone loss.
Our bodies are so incredibly adept at handling everything that the only evidence
of a «toxic» intestine,
kidney, liver, etc., will be evident on labs and imaging studies, and such
toxicities would require immediate treatment at a hospital because you will be very sick.
Adding a supplement on top
of kidney impairment could cause
toxicity.
Very Important for Cirrhosis
of the Liver, Emphysema, Environmental
Toxicity, Heart Attack, Jaundice,
Kidney Stones, Lead Poisoning, Lupus, Nail Problems, Radiation Exposure, and Tuberculosis.
Lentils and beans have the highest levels
of lectins and therefore can make us sick if we eat them raw [«
Toxicity of raw
kidney beans», Jaffe WG, Experientia 5 (1949) 81].
The risk
of silver
toxicity and argyria may be reduced if the total cumulative dosage is kept under one gram
of silver, especially if large doses are being consumed or there is
kidney or liver dysfunction present.
In a study titled Repeatedly heated palm kernel oil induces hyperlipidemia, atherogenic indices and hepatorenal
toxicity in rats: Beneficial role
of virgin coconut oil supplementation researchers from Ebonyi State University in Nigeria found that virgin coconut oil supplementation had a positive effect on the
kidneys and livers
of rats who were also fed repeatedly heated palm kernel oil.
Suppose the FDA told you about the multitude
of detailed scientific studies proving the soy estrogenic endocrine disruptor
toxicity causation
of (irreversible) autism, seizures, mental retardation, allergies, asthma, thymus damage, hypothyroidism, immune deficiency disorders, damage to pancreas, liver, and
kidney, diabetes, leukemia, multiple cancers, metastasis, gender chaos and infertility — pain and suffering for a lifetime.
Why wait until you are taking many different kinds
of drugs to control symptoms, drugs which are linked with
kidney and liver
toxicity?
Cooking at low temperatures can amplify the lectins, in fact, under cooking
kidney beans increases the
toxicity of lectins.
For healthy people with normal
kidney function, there is not any known risk
of toxicity from excessive dietary potassium under any circumstance.
Toxicity studies
of Blockol, a dietary supplement containing Phase 2 starch neutralizer (Phase 2), a standardized extract
of the common white
kidney bean (Phaseolus vulgaris)
In addition to diarrhea, magnesium can cause sedation, and symptoms
of magnesium
toxicity (again, quite unlikely if your
kidneys are in good shape) are low blood pressure, confusion, arrythmia, muscle weakness, and fatigue.
One
of the most serious complications
of grape / raisin
toxicity is acute (sudden)
kidney failure with lack
of urine production (anuria).
I do nt think previcox is way to go in this case, especially if autoimmune joint issue now, as well as potential
kidney toxicity of this drug.
Toxicities can cause the sudden development
of kidney failure within 48 hours
of snacking — and researchers still don't know exactly why.
Many
of us think that it is a pesticide or fungicide which is sprayed on the graoe that canh cause
kidney toxicity in some dogs.
Signs
of toxicity include loss
of appetite, vomiting, increased urination and excessive thirst due to
kidney failure.
What we do know is that the end result in nearly all reported cases
of grape or raisin
toxicity is acute
kidney failure.
Despite what some online sources may have led you to believe, pig flesh does not contain anything that is known to be poisonous to dogs — giving your furry friend a chunk
of pork is not likely to cause
kidney failure, shock, or any other symptoms
of toxicity.
Common conditions we see on an emergency basis include (but are not limited to) vomiting and diarrhea, congestive heart failure,
kidney failure, canine parvoviral enteritis (Parvo), complications from diabetes, pancreatitis, pneumonia, hepatic lipidosis (fatty liver disease), anemia, coagulopathies (like Rat Bait Poisoning), intervertebral disk disease / paralysis, rattlesnake envenomation, heat stroke, urinary obstruction,
toxicities, and various types
of trauma.
Plus, according to Khalsa, lab tests have shown that with longterm exposure at low doses, fipronil has the potential to cause nervous system and thyroid
toxicity, thyroid cancer, altered thyroid hormone levels, liver
toxicity,
kidney damage, convulsions, whining, barking, crying, loss
of appetite, locomotor difficulty, reduced fertility, fetus mortality, smaller offspring, loss
of hair at or beyond the point
of application, moist inflammation, chemical burn and itching.
Other causes
of blood in a pet's urine include
kidney infections, some cancers, feline leukemia, autoimmune disorders, blood clotting disorders, rodenticide poisoning and other
toxicities.
Answer: While antifreeze
toxicity runs through my mind first, dogs can vomit for a LOT
of different reasons: dietary indiscretion, GI viruses, toxins,
kidney disease, liver disease, foreign body, intestinal parasites, etc. etc. so you will need to visit your veterinarian and have some tests run.
It may be possible to avoid
toxicity of the
kidneys by beginning intravenous fluids promptly and supporting circulation despite the NSAIDs in the patient's system.
In many cases
of Deramaxx
toxicity a hospital stay will be required to monitor the patient's liver and
kidney functionality.
Blood and urines tests may be used to diagnose the severity
of toxicity or the presence
of kidney damage, but these tests are usually secondary to emergency treatment.
For example, Dr. Deva Khalsa points out that the active ingredients in several flea and tick treatments have been implicated in a variety
of health problems, including thyroid cancer,
kidney toxicity, nervous system issues, extreme lethargy and seizures.
Gentamicin, while absorbed poorly from the skin, when applied topically for long periods
of time to large wounds, burns or denuded skin has a potential for reversible or irreversible ear and
kidney toxicity.
Peak drug concentrations occur about 3 hours after ingestion, and the results
of toxicity include GI bleeding and
kidney failure.
ACT - activated clotting time (bleeding disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver,
kidney and intestinal disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal disorders) Allergy Testing intradermal or blood antibody test for allergen hypersensitivity ALT - alanine aminotransferase (liver disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (blood clotting ability) AST - aspartate aminotransferase (muscle and liver disorders) Band band cell — type
of white blood cell Baso basophil — type
of white blood cell Bile Acids digestive acids produced in the liver and stored in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice from liver disease or RBC destruction) BP - blood pressure measurement BUN - blood urea nitrogen (
kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (infection, drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete blood count (all circulating cells) Chol cholesterol (liver, thyroid disorders) CK, CPK creatine [phospho] kinase (muscle disease, heart disease) Cl - chloride ion — unbound chloride (hydration, blood pH) CO2 - carbon dioxide (blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced by the adrenal glands (adrenal gland function) Coomb's anti- red blood cell antibody test (immune - mediated hemolytic anemia) Crea creatinine (
kidney function) CRT - capillary refill time (blood pressure, tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical heart activity, heart arryhthmia) Eos eosinophil — type
of white blood cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake
of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound by protein measured by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver disorders) Glob globulin (liver, immune system) Glu blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup
of white blood cells Hb, Hgb hemoglobin — iron rich protein bound to red blood cells that carries oxygen (anemia, red cell mass) HCO3 - bicarbonate ion (blood pH) HCT, PCV, MHCT hematocrit, packed - cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (
kidney disorders, adrenal gland disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte — type
of white blood cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed - cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part
of the C&S that determines antimicrobial selection Mono monocyte — type
of white blood cell MRI magnetic resonance imaging (advanced tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red blood cell — immature red blood cell (bone marrow damage, lead
toxicity) PCV, HCT, MHCT packed - cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract infection, urolithiasis) Phos phosphorus (
kidney disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet — cells involved in clotting (bleeding disorders) PT prothrombin time (bleeding disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red blood cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red blood cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil — type
of white blood cell USG Urine specific gravity (urine concentration,
kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (
kidney function, urinary tract infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (
kidney disorders) VWF VonWillebrands factor (bleeding disorder) WBC white blood cell count (infection, inflammation, bone marrow suppression)
Since there are dogs that would seem more susceptible to the development
of severe
kidney damage after consumption
of even the smallest amounts
of grapes, it is thus imperative that you know more about grape
toxicity.
Gentamicin, while absorbed poorly from the skin, when applied topically to large wounds, burns, or denuded skin for prolonged periods
of time has a potential for reversible or irreversible ear and
kidney toxicity.
The veterinarian found evidence in the
kidneys and intestines
of all three cats that was consistent with NSAID
toxicity.
No one is completely sure what it is within grapes that cause such a high level
of toxicity in dogs, but it is well documented that some dogs that ingest them can experience
kidney failure and even death.