Sentences with phrase «of knockins»
While this is comparable or better than the efficiency of most current CRISPR - based approaches for the generation of knockins, it is not always ideal.
http://blog.addgene.org/ Not exact matches
I, too, share most of my baking with my next door neighbour and they're always super happy when I come a» knockin».
Keep on cookin»... you're knockin'these recipes out of the park!
So, under the present system, when that pol - to - be comes a knockin» you might as well entice them with a bottle of fine Irish influence because they'll just use the money to treat friends and family to a night on the town.
Chris Gibson is knockin» it out of the park.
It is this application - the creation of sequence - specific knockins - for which the AAV approach is most well suited, since it routinely generates knockin efficiencies of 1 - 40 % with G418 - selected clones.
Role of VGF - derived carboxy - terminal peptides in energy balance and reproduction: analysis of «humanized» knockin mice expressing full - length or truncated VGF.
Development of innovative mouse lines by targeted genome modification (knockin - knockout (KI / KO) approaches).
Using knockin point mutations in mice, Dr. Rudolph has demonstrated that anxiolytic and sedative actions of benzodiazepines, such as diazepam (Valium), are mediated by two distinct GABAA receptor subtypes and can thus be targeted separately pharmacologically.
To investigate the role of cleavage in vivo, we generated by gene targeting a Pkd1 knockin mouse (Pkd1 (V / V)-RRB- that expresses noncleavable PC1.
Disease progression was compared in three knockin mouse lines with similar CAG repeat expansion lengths of approximately 190 repeats, were compared at 2, 4, 6 and 10 months of age utilizing PsychoGenics proprietary cubes platform technologies: PhenoCube ®, Smart Cube ® and Neurocube ® as well as standard behavioral testing paradigms including Open Field and Tapered Balance Beam.
Transgenic and gene knockout / knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.
Reconstruction of transgenic and gene knockout and knockin mouse models of human diseases.
Their experts had very good understanding of our scientific objective and their thorough analysis helped us to design an effective genetic strategy based on Rosa26 Quick Knockin.
Given that many recent studies of B cell biology take advantage of Ig - transgenic (or knockin equivalent) mice for their entire analysis, we do not feel that our use of the approach as one part of the present study is out of line with currently accepted practice in the field.
The album's just a little over half - an - hour long, and it's all of a piece, conveying casual imagery that meanders from the hands - in - pockets wistfulness of drifting and kicking on trash cans («Knockin» on Your Screen Door») to turning on the TV and looking out your window.
Knockin» On Heaven's Door — Film versions of anime TV series don't have a particularly good history.
Reckless Life Nice Boys Move To The City (Live) Mama Kin Shadow Of Your Love (Live) Welcome To The Jungle (1986 Sound City Session) * Nightrain (1986 Sound City Session) * Out Ta Get Me (1986 Sound City Session) * Paradise City (1986 Sound City Session) * My Michelle (1986 Sound City Session) * Shadow Of Your Love * It's So Easy (Live) Knockin» On Heaven's Door (Live) Whole Lotta Rosie (Live) You're Crazy (Acoustic Version) Patience Used To Love Her Move To The City (1988 Acoustic Version) *
Titles to suggest for research include: Baby Flo, by Alan Schroeder; Ray Charles, by Sharon Bell Mathis; When Marian Sang: The True Recital of Marian Anderson, by Pam Muñoz Ryan; Ella Fitzgerald: The Tale of a Vocal Virtuosa, by Andrea Davis Pinkney; Knockin» On Wood: Starring Peg Leg Bates, by Lynne Barasch; Paul Robeson, by Eloise Greenfield; Sweet Music in Harlem, by Debbie A. Taylor; Rent Party Jazz, by William Miller; Charlie Parker Played Be Bop, by Christopher Raschka; Dizzy, by Jonah Winter; When Louis Armstrong Taught Me Scat, by Muriel Harris Weinstein; Duke Ellington: The Piano Prince and His Orchestra, by Andrea Davis Pinkney; Rap A Tap Tap: Here's Bojangles — Think of That!
Results of the first Knockin» Books poll have been tabulated and the numbers tell a clear story.
My friends and I have been running Knockin» Books for over a year and in that relatively short time, we've been lucky enough to interact with a lot of authors both self - and traditionally - published.
With a script penned by Alex Garland (28 days later), voice acting by Lindsay Shaw (10 things I hate about you) and Andy Serkis (Lord of the Rings) IF the game were to become a commercial success, Hollywood might come» a knockin»..
The exhibition «Knockin» on Heaven's Door» at the Kunstmuseum in Vaduz, Liechtenstein, explores contemporary artistic representations of body / soul, body / mind, matter / consciousness.