The story
of kuru, as classically told in biology textbooks, is a tragic one.
The example
of kuru helped to show how BSE — mad cow disease — spread through the feeding of infected...
The laureate acted out stages
of kuru, which often causes victims to shake or laugh spontaneously.
The example
of kuru helped to show how BSE — mad cow disease — spread through the feeding of infected cattle brains to other animals, and how this led to variant Creutzfeldt - Jakob disease (vCJD).
Not exact matches
But transgenic mice with the codon - 127 mutation were completely resistant to
kuru and CJD regardless
of whether they bore one or two copies
of it.
In the most famous example
of cannibalism - related disease transmission, the Fore people
of New Guinea were nearly driven to extinction as a result
of their ritualized consumption
of brains and other tissues cut from the bodies
of their deceased kin — kin who had been infected by
kuru, an incurable and highly transmissible neurological disease.
In an article entitled «Prion protein modulates monoaminergic systems and depressive - like behavior in mice» and published in the Journal
of Biological Chemistry, the group shows that mice lacking normal prions show a depressive - like behavior similar to depression symptoms found in patients with Alzheimer's and prion diseases, namely Creutzfeldt - Jakob Disease (CJD), variant Creutzfeldt - Jakob Disease (vCJD), Gerstmann - Sträussler - Scheinker syndrome, Fatal Familial Insomnia and
kuru.
The scourge
of the Fore was a disease they called
kuru, a degenerative and always fatal brain disease contracted by eating the corpse
of a previous sufferer.
The new finding offers direct, physical evidence supporting protein - based inheritance, thus strengthening the «prion hypothesis»
of the cause
of neurodegenerative diseases in mammals, such as sheep scrapie, mad cow disease (or bovine spongiform encephalopathy) and the
kuru disease
of the Papua New Guinea tribes.
The main character
of The People in the Trees is based on a real man named Carleton Gajdusek, who spent much
of the 1950s in Papua New Guinea, working with a tribe called the South Foré, who were beset with a mysterious and fatal neurodegenerative disease they called «
kuru,» or the shaking.
And while
kuru is
of course a singular condition, its cousins — including mad cow and scrapie — are the stuff
of everyday Western life, and it was for this discovery that he was awarded the Nobel Prize in Physiology or Medicine in 1976.