As a first step, his team is testing whether it's possible to stop or slow tau - driven neuron loss and inflammation by lowering ApoE in the early life
of laboratory rodents.
Not exact matches
When he offered the fruits
of those labors to
laboratory packrats and cactus mice, the
rodents ate the mild chilies but avoided the hot ones.
Defence Science and Technology
Laboratory (DSTL), whose goal is to create «battle - winning technologies» for the Ministry
of Defence, has registered a 17 % increase in experiments on pigs, rabbits, monkeys and
rodents over the last two years.
More than 160 papers were published on
rodent enrichment in 2016 versus a handful at the turn
of the millennium; at the 2016 meeting
of the American Association for
Laboratory Animal Science, 83 out
of 171
rodent presentations focused on enrichment — more than twice the number at the 2009 meeting.
They then induced Parkinson's symptoms in
laboratory rats by killing the
rodents» dopamine - producing neurons with toxins, and injected the viruses into the damaged tissue
of some
of the animals.
Experimental research on drugs, immunology, and the development
of malaria is typically done on related Plasmodium species that infect
rodents, including
laboratory - reared mice.
While studying the inflammatory mechanisms underlying colitis in
rodents, a team
of researchers led by Dana Philpott and Thierry Mallevaey realized that their
laboratory mice were more susceptible to developing the disease if their intestines were already infected with the protozoan Tritrichomonas muris.
Scientists have found a way to make simple droplets
of oil navigate complex labyrinths with the same skill as
laboratory rodents.
In particular, Panksepp's work has focused on «the possibility that our most commonly used animal subjects,
laboratory rodents, may have social - joy type experiences during their playful activities and that an important communicative - affective component
of that process, which invigorates social engagement, is a primordial form
of laughter.»
And that could be bad if what happens in
laboratory animals also happens in people, because studies in
rodents show that BPA can trigger a host
of harmful changes, from reproductive havoc to impaired blood - sugar control and obesity (SN: 9/29/07, p. 202).
As part
of the team studying poststroke dementia in Dr. Kristian Doyle's
laboratory, Dr. Nguyen applies more than 10 years
of experience in quantifying neurodegeneration, immune responses, and behavior in
rodent models.
In the
laboratory, the researchers exposed juvenile
rodents to a single session
of unpredictable stress.
In
laboratory tests using
rodents, White and his colleagues found that while morphine lost its pain - relieving effectiveness three weeks after nerve injury, a combination therapy
of morphine and carbamazepine — used to prevent epileptic seizures — could effectively reverse this loss
of drug action.
General Product Information Obesity - High Fat Diets for Diet - Induced Obesity Models Metabolic Syndrome - Diet - Induced Metabolic Syndrome in
Rodent Models Diabetes - High Fructose / Sucrose Diets for inducing Hypertriglyceridemia and Insulin Resistance in
Rodents Atherosclerosis - Diet - Induced Atherosclerosis / Hypercholesterolemia in
Rodent Models Hypertension - Phenotypic Expression
of Hypertension in
Rodent Models through Dietary Manipulation NAFLD (Non-alcoholic Fatty Liver Disease) Cancer - Creating a Clean Background for Oncology Research Test Compounds / Kaolin Pellets Diet and Immunology Focus: Arsenic in Grain - Based
Laboratory Animal Diets and Effects on the
Rodent Toxicological Phenotype Focus: The Importance
of a Proper Control Diet
«
Laboratory rodent diets contain toxic levels
of environmental contaminants: implications for regulatory tests» by Robin Mesnage et al. published in PLOS ONE on Thursday 2 July 2015.
In my previous work, in the
laboratory of Stéphanie Lacour at EPFL, we pioneered an electronic device chronically integrated on the surface
of the spinal cord (and brain) in
rodents (Minev at al, Science 2015).
Dosing Animals Via Diet Measuring Food and Water Intake in Rats and Mice
Laboratory Animals - A Critical Part
of In Vivo Research Diet - Induced Metabolic Syndrome in
Rodent Models
In
laboratory research,
rodent models
of seizure activity, typically differentiate between absence seizures (a type
of generalized epilepsy, in which electrical activity
of the entire brain is affected), and mesial temporal lobe epilepsy (a type
of partial epilepsy, which only affects one hemisphere
of the brain).
A consortium
of researchers from North Carolina State University, Texas A&M, USDA, CSIRO (in Australia), and Island Conservation are in a proof -
of - concept phase
of developing and testing genetic systems
of this sort in the
laboratory to precisely eliminate invasive
rodents from sensitive ecosystems.
The scientists said they created their mice from the brain cells
of rodents that had been kept in
laboratory conditions at -20 C.
The Dodt and Frank Bradke
laboratories later developed the 3DISCO (3 - dimensional imaging
of solvent cleared organs) method
of imaging
rodent brains and spinal cords by combining Ultramicroscopy with tetrahydrofuran - based tissue clearing (13,14).
He spent his basic research career studying the mechanisms
of steroid hormone action on the brain, behavior, and mental health, and the influences
of the environment and stressors on those actions in
laboratory rodents.
During this time, I have been actively engaged in clinical studies
of participants that have been diagnosed with glaucoma or high - risk ocular hypertension, as well as in
laboratory - based studies on experimental glaucoma models in
rodents and non-human primates.
Laboratory Animals publish this month a paper summarising the findings
of an NC3Rs expert working group who have been investigating the impact
of rodent age on study outcomes.
In this study, we begin the empirical effort to determine the likely direction
of immune - mediated virulence evolution by performing experimental evolution
of the
rodent malaria parasite, Plasmodium chabaudi, in
laboratory mice.
The current findings are «another piece
of evidence that what we see in
laboratory rodents on caloric restriction translates to humans,» said Richard Weindruch, PhD,
of the University
of Wisconsin — Madison, who has studied caloric restriction since 1975 but did not participate in Floel's study.
Fructose maintains a low glycemic index
of 23 and a low glycemic load, but paradoxically it is routinely used to induce insulin resistance in
laboratory rodents at high (35 — 65 %
of energy) dietary concentrations (85,86).
«Unlike
laboratory rodents, dogs share a common environment with people and, therefore, may be exposed to some
of the same carcinogens.
Her love
of pocket pets grew during her undergraduate years while working with her college's
laboratory rodents.
At least in
laboratory rodents, high fat diets are no friend
of the kidneys.
The Veterinary Clinical Pathology
Laboratory offers hematology, coagulation, and biochemical testing, urinalysis, and body fluid analysis for a variety
of species, including dogs, cats, horses, cows, pigs, poultry, camelids,
rodents, non-human primates, reptiles, and fish.
It should be mentioned that traditional
laboratory rodents usually do not display pair bond formation, a behavioral characteristic that is displayed by less than 5 %
of mammalian species (Kleiman, 1977; Dewsbury, 1988).