Sentences with phrase «of lead compounds»

MacCoss and Baillie (p. 1810) outline how the synthesis of more effective analogs of lead compounds now takes many cues from the more readily obtained data on bioavailability and toxicity.

«For drug discovery and development, you need to make variants of lead compounds.

From the test results of each chemical iteration of the lead compound, they were able to alter their chemical structures to make them much more potent.

The trial uses FDG - PET imaging to examine the potential of its lead compound, LMTX ®, in delaying the progression of disease pathology in the brain.

Not exact matches

John McAfee, founder of a leading anti-virus software company that still bears his name, went off the compound — literally — causing a maelstrom of bad press as he eluded police.

And these problems were compounded by the parallel objectives of some of the other leading European factions.

But, as money and weight can quickly compound and double — the emotional and mental burden of these negative thoughts can lead to similar compounding effects which will diminish the quality of your self - worth and life.

And that story was partly influenced by the Central Intelligence Agency, which gave Bigelow and her producers unprecedented access to the agency's classified documents on the intelligence that led to both the finding of bin Laden and the raid on the Al Qaeda leader's compound.

It also gives you recurring opportunities to reach out to an interested, dedicated lead pool, giving you compounding returns as your number of subscribers grows.

The Economist extrapolates that even a 2 percent bump on a $ 45,000 a year salary can lead to as much as an extra $ 67,000 over the course of a 40 - year working career, if you were to set aside your language bump in savings and figure in compound interest.

This «interest» never actually left the partnership — instead, Buffett's investors reinvested all profits, which led to compound growth of the partnership's assets over time.

«This question is significantly compounded by the complete lack of any documentation about the process leading up to the termination,» Cook wrote in his ruling, released August 22.

«To his son, [Shelby] Davis passed along his infectious passion for owning shares in carefully chosen companies (he called them «compounding machines»), his conviction that owning the best compounding machines would lead to unimagined rewards, his distrust of unnecessary spending (why waste money they could be invested?)

Workshop participants first learn to embrace the benefits of positive performance they then share them naturally with co-workers leading to a compounding effect inside the organization.

This emptiness is being compounded by the student - led efforts to purge historic universities of morally suspect memories.

Romany and Ryan, union of hindu's, ignorant s, One hindu ignorant pseudo Jew, self centered and other, a hindu ignorant Catholic compounded gentile, slave of hindu Jew's, filthy secular's, Lord have mercy on USA, hindu, blind leading hindu's, blinds labeled as Christians.

Moreover, we are sometimes afflicted with a sense of impending crisis, lending force to Niebuhr's observation that «one of the most pathetic aspects of human history is that every civilization expresses itself most pretentiously, compounds its partial and universal values most convincingly, and claims immortality for its finite existence at the very moment when the decay which leads to death has already begun.»

This led to the formation of «mission compounds» and social ghettos where Christians could take their place as one more subcaste or subsect among the thousands of such subcastes and subsects in India.»

The minds and wills of all the people must be prepared by education to find some way, not yet apparent, out of the collective insanity into which our compounded knowledge, fear, and hostility have led us.

About Barry Callebaut Group (www.barry-callebaut.com): With annual sales of about CHF 6.2 billion (EUR 5.6 billion / USD 6.6 billion) in fiscal year 2014/15, the Zurich - based Barry Callebaut Group is the world's leading manufacturer of high - quality chocolate and cocoa products — from sourcing and processing cocoa beans to producing the finest chocolates, including chocolate fillings, decorations and compounds.

Chocolate has been reconsidered recently as a source of healthy compounds, according to lead author and Penn State associate professor of food science Dr Joshua Lambert.

Some of this leftover sugar is caramelized during baking, leading to numerous additional flavor compounds that increase the flavor of the loaf.

As the world's leading cork producer, Amorim has stood at the forefront of the fight against TCA — a naturally forming chemical compound that is a problem in the packaged food and beverage industries — through the application of rigorous production standards and certified quality control methods.

Tara Jensen hosts a monthly pizza night, and every time she's sure that no one will come, and every time, nearly 100 people show up, finding their way to the town of Marshall, North Carolina, then heading six miles northwest on Route 70 along the French Broad River, winding around the knoll called Walnut, and stopping at the dirt driveway leading to her compound, which consists of an algae - covered pond, a shack in the woods, a brick oven, and two pitched - roof houses, one of which is a bakery that goes by the name of Smoke Signals.

Barry Callebaut: With annual sales of about CHF 4.9 billion (EUR 4.0 billion / USD 5.2 billion) in fiscal year 2012/13, Zurich - based Barry Callebaut is the world's leading manufacturer of high - quality chocolate and cocoa products — from sourcing and processing cocoa beans to producing the finest chocolates, including chocolate fillings, decorations and compounds.

Barry Callebaut: With annual sales of about CHF 5.9 billion (EUR 4.8 billion / USD 6.5 billion) in fiscal year 2013/14, the Zurich - based Barry Callebaut Group is the world's leading manufacturer of high - quality chocolate and cocoa products — from the origination and processing cocoa beans to producing the finest chocolates, including chocolate fillings, decorations and compounds.

There is racial inequity: less of the overall resources are ending up in predominantly black neighborhoods, which leads to compounding issues in many areas, be it health, law, education... you get the idea.

Liverpool skipper Steven Gerrard's failure to qualify for the FA Cup final on his birthday could be further compounded by the painful reality that he could be leading his team in a guard of honour for champions - elect Chelsea at Stamford Bridge next month, the Daily Mail reports.

«We should see lions,» Harry said as we moved out of the compound and onto the sand road leading north to his concession.

Last time out they drew 0 - 0 with rock - bottom Wigan − the second consecutive game (tenth overall) in which they had failed to find the back of the net, a dreadful result that was compounded by the news Darren Bent had picked up a serious injury that would sideline the club's leading scorer for the remainder of the term.

Bob Boutin, president of Skokie - based Knechtel Labs, a leading confectionary and food consultant, cautioned that brominated vegetable oil is an umbrella term that can be applied to different oils that may have been treated in a variety of ways, creating a wide variety of compounds used for different purposes.

Hovet's traumatic birth, compounded by the trauma of her abuse, led to a diagnosis of «complex PTSD» that she wrestles with to this day.

In Northern Ireland, the election compounds the political turmoil, which followed the failure of the DUP - led power - sharing government, electoral losses for the DUP, and the subsequent inability of the unionist and nationalist parties to come to a new agreement.

«Sleep well Mr. Governor, with the knowledge that your action has compounded the loss of their loved ones and renewed the anguish and insufferable pain of the wanton murders of their family members by Judith Clark and her co-conspirators,» said James Stewart, the lead investigator for the Rockland County DA's office.

We advised that the Buhari led government should ensure an improvement in electricity supply first as increase in tariff, establishment of various taxes without justification among others will only compound the sufferings of Nigerians.

The discovery of another almost N15bn from the Osborne Ikoyi, Lagos luxury apartment appears to have put the Presidency on the spot; compounding what are turning out to be a burgeoning credibility and public relations burdens for the APC - led federal government.

Some of the reactions lead to the release of flavour compounds and other organoleptic property - altering compounds all of which affect how we perceive the food as we enjoy...

During cooking, a lot of interesting chemical reactions occur which lead to the formation of some other chemical compounds which were neither components of the raw food material nor nutrients in themselves.

Oneida County Health Department (OCHD) warns parents and caregivers not to buy or use Bo Ying Compound, due to the potential risk of lead poisoning.

It was not one failure which led to his death; it was generations of failures compounded on one another.»

The President said that besides the menace of Boko Haram, the concept of host and settler communities had compounded the migration problem in the country, leading to clashes.

The trio of BalogunLukman, a resident of No. 3 K&S street, Ikotun Lagos, Sunday Kayode 39 yrs resident of Isheri Compound Lagos and AtandaAbiodun of No. 25 Egbeda / Akowonjo Road, Bakery bus - stop Lagos were arrested on the 27th of April by Police patrol team of Ishara Division led by the DPO CSP Ysusf Taiwo.

His defeat in compounded Labour's woes in a dismal night, which saw the party lose all but one of its Scottish MPs and will undoubtedly lead to Ed Miliband standing down.

(CNN)- Rep. Michael Grimm on Monday likened the recent bombings in southern Russia to the security threats leading up to the deadly 2012 attack on a U.S. compound in Benghazi, Libya, as well as red flags ahead of the Boston Marathon bombings.

«Simply put, the compound turns - off the sperm's ability to swim, significantly limiting fertilization capabilities,» said lead investigator Michael O'Rand, PhD, retired professor of cell biology and physiology in the University of North Carolina at Chapel Hill School of Medicine, and president / CEO of Eppin Pharma, Inc. «This makes EP055 an ideal candidate for non-hormonal male contraception.»

Now, testing of that compound is leading to a better prognosis for mice with the disease and the possibility of potential drugs that will improve outcomes for patients with SMA.

To get around that problem, a group at the Department of Energy's Ames Laboratory in Iowa, led by Vitalij Pecharsky — a materials scientist with a joint appointment at Iowa State University, Ames — started with powdery organic compounds, such as phosphonium salts, solid aldehydes or ketones, and anhydrous potassium carbonate.

To try to develop a more sensitive probe for isolating individual peptides — short strands of amino acids — from a pool of similar molecules, a team led by chemist Clark Still of Columbia University 4 years ago synthesized small organic compounds that selectively fish out peptides dissolved in chloroform.

A team led by Stuart Licht at the Technion - Israel Institute of Technology in Haifa has come up with a new cathode made from unusual iron - based molecules — iron (VI), or «super-iron,» compounds — that absorb more electrons than manganese dioxide.

Mercury, lead, chromium and other toxic compounds, used in many industrial processes, rob years of healthy life from millions each year.