Daley, one
of the leading stem cell researchers in the country, feels as if he has been treading water for years.
An international group
of leading stem cell researchers has issued a statement that specifies concerns about the development and use of unproven stem cell therapies.
Not exact matches
The Ontario Institute for Regenerative Medicine (OIRM) is part
of a community
of researchers and organizations that are making world -
leading scientific discoveries in
stem cell and regenerative medicine.
In a groundbreaking study that provides scientists with a critical new understanding
of stem cell development and its role in disease, UCLA researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research led by Dr. Kathrin Plath, professor of biological chemistry, have established a first - of - its - kind methodology that defines the unique stages by which specialized cells are reprogrammed into stem cells that resemble those found in the emb
stem cell development and its role in disease, UCLA researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research led by Dr. Kathrin Plath, professor of biological chemistry, have established a first - of - its - kind methodology that defines the unique stages by which specialized cells are reprogrammed into stem cells that resemble those found in the emb
cell development and its role in disease, UCLA
researchers at the Eli and Edythe Broad Center
of Regenerative Medicine and
Stem Cell Research led by Dr. Kathrin Plath, professor of biological chemistry, have established a first - of - its - kind methodology that defines the unique stages by which specialized cells are reprogrammed into stem cells that resemble those found in the emb
Stem Cell Research led by Dr. Kathrin Plath, professor of biological chemistry, have established a first - of - its - kind methodology that defines the unique stages by which specialized cells are reprogrammed into stem cells that resemble those found in the emb
Cell Research
led by Dr. Kathrin Plath, professor
of biological chemistry, have established a first -
of - its - kind methodology that defines the unique stages by which specialized
cells are reprogrammed into
stem cells that resemble those found in the emb
stem cells that resemble those found in the embryo.
Researchers led by Patricia Donahoe and Xiaolong Wei
of Massachusetts General Hospital and Harvard Medical School found that the common chemotherapy agent doxorubicin actually encourages the growth
of ovarian cancer
stem cells.
Now
researchers led by neurologist Michelle L. Monje
of Harvard University have found the root
of these cognitive difficulties: damaged
stem cells.
Researchers,
led by Joshua Mayourian at the Icahn School
of Medicine at Mount Sinai, used mathematical modeling to simulate electrical interactions between these
stem cells and heart
cells to develop insight into possible adverse effects, as well as to hypothesize new methods for reducing some potential risks
of this therapy.
Enabling scientists to grow the
stem cells artificially from pluripotent
stem cells could also
lead to the development
of personalized blood therapies,
researchers say.
Today Wagers, 35, is a
leading researcher of adult
stem cells — those that generate blood and muscle.
In 2011,
researchers led by David Baker, a computational biologist at the University
of Washington in Seattle, created a designer protein that binds HA's
stem, which prevented viral infection in
cell cultures.
The reason, say
researchers: the hormone stimulates production
of more oligodendrocyte
stem cells,
leading to more oligodendrocytes and therefore more myelin.
Of particular interest to
stem cell and regenerative medicine
researchers, the finding may
lead to laboratory methods to create heart
cells that function more like those found in adult hearts.
That debate is in full force this week as
researchers led by Kui Liu at the University
of Gothenburg in Sweden say they have ruled out the tantalising possibility that ovarian
stem cells exist.
The only previous demonstration — by
researchers led by Shou - Wei Ding, PhD, a professor
of Plant Pathology and Microbiology at UC Riverside and co-corresponding author
of the current study — was done in embryonic
stem cells and in newborn mice.
That's the hope
of researchers led by Yuet Kan
of the University
of California, San Francisco — and they have proved the basic principle, altering the genome
of induced pluripotent
stem cells (iPSCs) to give them a rare natural mutation that allows some people to resist HIV.
The
researchers from UC Berkeley, UC San Francisco Benioff Children's Hospital Oakland Research Institute (CHORI) and the University
of Utah School
of Medicine hope to re-infuse patients with the edited
stem cells and alleviate symptoms
of the disease, which primarily afflicts those
of African descent and
leads to anemia, painful blood blockages and early death.
Now, a team
led by neurotransplant
researcher Ole Isacson
of Harvard Medical School in Boston reports that
stem cells can compensate for some Parkinson's - like damage in animals.
Researchers hope that the results, published separately in the Journal
of Clinical Investigation and
Cell Stem Cell, will
lead to new, «personalized medicine» approaches to treating lung disease.
After other
researchers reported that bone marrow
stem cell therapy
led to a modest but promising 5 percent improvement in the regeneration
of sensory nerve fibers in rats with spinal cord injuries, he performed a critical reality check.
In 2008 a group
of medical
researchers led by Robert Lanza at Advanced
Cell Technology in Worcester, Massachusetts, reported another leap: They discovered a way to avoid destroying the embryo by deriving an entire stem cell line from a single embryonic c
Cell Technology in Worcester, Massachusetts, reported another leap: They discovered a way to avoid destroying the embryo by deriving an entire
stem cell line from a single embryonic c
cell line from a single embryonic
cellcell.
British newspapers reported this weekend that Ian Wilmut, the University
of Edinburgh biologist who
led the team that in 1997 cloned Dolly the sheep, is getting out
of the cloning business in light
of the new findings, which seem to offer
researchers a likely new source
of stem cell lines for basic research that could one day
lead to new treatments and perhaps cures for spinal injuries, diabetes and debilitating disorders such as multiple sclerosis and Parkinson's disease.
In a new study published in Scientific Reports, Tokyo Medical and Dental University (TMDU)-
led researchers investigated photodynamic detection
of cancer
stem cells in a glioma
cell line, a model
of a highly aggressive type
of brain cancer.
The reality, say
leading stem cell researchers, is that every disease and disorder needs its own special formula, including just the right promoter chemicals given at just the right dose, and just the right kind
of stem cells introduced at just the right stage.
Wanting to understand what happens under chronic inflammation conditions, a team
of researchers led by Freddy Radtke at EPFL's Swiss Institute for Experimental Cancer Research (ISREC) studied
stem cells in the corneas
of mice.
A group
of researchers led by Kosuke Fujita, Visiting
Researcher and Akito Maeda, Specially Appointed Professor at the HP Skin Regeneration, PIAS Collaborative Research, Osaka University clarified that cinnamtannin B - 1, or vegetable - based polyphenol, promotes the migration
of Mesenchymal
Stem Cells (MSCs) in blood circulation and accumulates them in damaged tissues (Fig. 1) to improve wound healing.
Scientists were even more stunned in July 2002 when
researchers led by
stem cell biologist Catherine Verfaillie at the University
of Minnesota reported that bone marrow — derived
cells they had injected into young embryos contributed to all three embryonic layers, just as embryonic
stem cells would do.
Researchers have known that aberrations in the methylation
of hematopoietic, or blood - forming,
stem cells (HSCs) can prevent them from differentiating into mature blood
cells,
leading to AML.
A new test may reveal which patients will respond to treatment for graft versus host disease (GVHD), an often life - threatening complication
of stem cell transplants (SCT) used to treat leukemia and other blood disorders, according to a study
led by
researchers at the Icahn School
of Medicine at Mount Sinai and published online today in the journal Lancet Haematology and in print in the January issue.
«The induced pluripotent
stem cells we used in this study proved to be extremely useful in disease modelling, and they could offer an excellent platform for drug discovery and testing new therapeutic targets for Alzheimer's disease in the future,» says Early Stage
Researcher Minna Oksanen, the
lead author
of the study.
These lines are available for
researchers funded by the US National Institutes
of Health (NIH) and the California Institute for Regenerative Medicine (CIRM) in San Francisco, says Jeremy Crook, a
stem cell biologist at the University
of Melbourne, Australia, who
led the team that made the lines.
In the new study,
led by
researchers at the Chinese Academy
of Sciences in Beijing and Nanjing Medical University in China and published today in
Cell Stem Cell, no transplantation was necessary.
Using cutting edge «disease in a dish» technologies, the
researchers are now following up the
leads discovered in blood
cell lines in neurons induced from
stem cells derived from the blood
of PMDD patients — in hopes
of gaining a more direct window into the ESC / E (Z) complex's role in the brain.
UCLA
researchers led by Drs. Peiyee Lee and Richard Gatti at the Eli and Edythe Broad Center
of Regenerative Medicine and
Stem Cell Research have used induced pluripotent stem cells (iPSC) to advance disease - in - a-dish modeling of a rare genetic disorder, Ataxia Telangiectasia (A
Stem Cell Research have used induced pluripotent
stem cells (iPSC) to advance disease - in - a-dish modeling of a rare genetic disorder, Ataxia Telangiectasia (A
stem cells (iPSC) to advance disease - in - a-dish modeling
of a rare genetic disorder, Ataxia Telangiectasia (A-T).
Researchers from the University
of Cambridge studied a variety
of cell lines, including human neural
stem cells, to investigate how Zika virus infection can
lead to microcephaly.
Refusing to give up the search, another team
of researchers at the University
of Toronto
led by Derek van der Kooy looked for
stem cells in pancreatic
cells from adult mice.
Expanding from their previous studies with mice, the
researchers first established that under specific conditions, culturing human embryonic
stem cells with fibroblast growth factor 2 (FGF2)
leads to neural differentiation particular to the midbrain / hindbrain region — the location
of the cerebellum — within three weeks, and the expression
of markers for the cerebellar plate neuroepithelium — the part
of the developing nervous system specific for the cerebellum — within five.
In the meantime, Takebe and the rest
of the team,
led by Hideki Taniguchi, also a
stem -
cell biologist at Yokohama City University — who are collaborating on the project with
researchers at Sekisui Medical, a biotechnology firm based in Tokyo — hope that his liver bud could be useful for toxicity testing in drug screening, for which bile ducts are not needed.
Using induced pluripotent
stem cells (iPSCs), a team
led by Mount Sinai
researchers has gained new insight into genetic changes that may turn a well known anti-cancer signaling gene into a driver
of risk for bone cancers, where the survival rate has not improved in 40 years despite treatment advances.
Now, in a study published in Nature,
researchers led by Professor Cédric Blanpain at the Université Libre de Bruxelles, Belgium, and Professor Ben Simons at the University
of Cambridge, have demonstrated in mice how skin
stem and progenitor
cells respond to the activation
of an oncogene.
The
researchers,
led by Benjamin Humphreys, MD, PhD, found that a rare population
of stem cells located outside
of blood vessels in mice become myofibroblast
cells that secrete proteins that cause scar tissue.
A team
of researchers led by scientists at Cold Spring Harbor Laboratory have for the first time identified
stem cells that allow the pituitary glands
of mice to grow even after birth.
Lead researcher Dr Gordana Vunjak - Novakovic said: «The availability
of personalised bone grafts engineered from the patient's own
stem cells would revolutionise the way we currently treat these defects.»
A team
of researchers led by Dr. Wei Yao
of the University
of California, Davis sought to build new bone tissue by directing mesenchymal
stem cells to outer bone more quickly.
Lead researcher Christoph Lepper, a predoctoral fellow in Carnegie's Chen - Ming Fan's lab and a Johns Hopkins student, for the first time looked at these two genes in promoting
stem cells at varying stages
of muscle growth in live mice after birth.
Researchers from the Sloan - Kettering Institute,
led by Dr. Lorenz Studer, have discovered a novel type
of neural
stem cell, which has a broader differentiation potential than previously identified neural
stem cells.
Complaining in particular that «unreasonable or obstructive reviews» and reliance on a limited group
of reviewers
led to the publication
of truly original research being delayed or prevented, Professor Smith organised the writing
of a letter
of protest, which was signed by a group
of key
stem cell researchers and sent to
leading journals.
In an effort to reign in the hype surrounding
stem cell research that has led to a proliferation of unapproved and potentially dangerous stem cell therapies, the International Society for Stem Cell Research (ISSCR) recently released updated guidelines outlining conduct for stem cell researchers that, for the first time, included communications activit
stem cell research that has led to a proliferation of unapproved and potentially dangerous stem cell therapies, the International Society for Stem Cell Research (ISSCR) recently released updated guidelines outlining conduct for stem cell researchers that, for the first time, included communications activit
cell research that has
led to a proliferation
of unapproved and potentially dangerous
stem cell therapies, the International Society for Stem Cell Research (ISSCR) recently released updated guidelines outlining conduct for stem cell researchers that, for the first time, included communications activit
stem cell therapies, the International Society for Stem Cell Research (ISSCR) recently released updated guidelines outlining conduct for stem cell researchers that, for the first time, included communications activit
cell therapies, the International Society for
Stem Cell Research (ISSCR) recently released updated guidelines outlining conduct for stem cell researchers that, for the first time, included communications activit
Stem Cell Research (ISSCR) recently released updated guidelines outlining conduct for stem cell researchers that, for the first time, included communications activit
Cell Research (ISSCR) recently released updated guidelines outlining conduct for
stem cell researchers that, for the first time, included communications activit
stem cell researchers that, for the first time, included communications activit
cell researchers that, for the first time, included communications activities.
A team
of researchers at the University
of Southern California grew
stem -
cell membranes in a sterile lab for a month and then inserted them into the eyes
of four people with «dry» macular degeneration, the
leading cause
of blindness in developed countries.
The Lawsuit Obama's new policy quickly provoked a lawsuit,
led by Nightlight Christian Adoptions and two adult -
stem -
cell researchers, Dr. James L. Sherley (a former MIT
researcher who notoriously went on a hunger strike after being denied tenure) and Dr. Theresa Deisher (president and founder
of Sound Choice Pharmaceutical Institute).
In addition, the EuroSyStem Project has created the European
Stem Cell Group, a network
of leading and emerging
researchers who have become Associate Principal Investigators with the project.