Sentences with phrase «of lever presses»

In one set of tests designed to quantify how much the rats desired each drug, they could get another infusion only by making ever - greater numbers of lever presses.

Not exact matches

The EC has a specific lever to press the US on this point — in the form of the Privacy Shield arrangement which simplifies the process of authorizing personal data flows between the EU and the US by allowing companies to self - certify their adherence to a set of privacy principles.

«At this point, I am very confident that we now clearly understand and have our hands placed securely on the practical levers that we believe will enable us to continue to drive double - digit rates of unit and revenue growth for some time,» said Chip Perry, TrueCar's president and CEO, in a press release on Thursday.

By virtue of their public nature, resolutions can be an effective press / PR lever.

There are many other tactics shareowners use as levers including, investor statements endorsed by a broad group of institutional investors; direct outreach to other shareholders; proxy voting services; and other investment advisors to gain support for specific shareholder proposals; and, outreach to consumers and the press as a way to draw public attention to an issue or a company.

Fr James Tolhurst Chislehurst, Kent The Trinity: An Introduction to the Catholic Doctrine on the Triune God By Giles Emery OP, trans Matthew Levering, The Catholic University of America Press, 2011, 219pp, $ 24.9 J Anyone educated in theology in the last 30 years might be forgiven for thinking that Trinitarian speculation began with Karl Rahner.

Suggested advice for parents is to «Look for a toy that is 10 percent toy and 90 percent child — «A lot of these toys direct the play activity of our children by talking to them, singing to them, asking them to press buttons and levers,» Hirsh - Pasek says.

With many of the low - end pumps, you must regulate the suction and cycles manually by pressing a lever or placing and removing your fingers over a port.

The Dekor lid opens with a press of your foot on a lever at the bottom, like a kitchen garbage can.

The folding process requires you to pull up on the safety grip on the handle and also press the lever on the side of the handlebar while pressing down on the handle.

It is accomplished by raising the lever located at the base of the handle and simultaneously pressing with your foot where it says «Fold».

Just release the locking levers on each side of the handlebar and press down on the handlebar until you hear a click.

Look for a toy that is 10 percent toy and 90 percent child — «A lot of these toys direct the play activity of our children by talking to them, singing to them, asking them to press buttons and levers,» Hirsh - Pasek says.

Sure enough, profiles appeared in the press touting the speaker's tough contrarian stance, and Mark - Viverito was given a lever to obtain some crack of daylight between her and de Blasio.

For one of the treats, scientists gradually increased the amount of effort required for the payoff — from one lever - press to five, then 10, then 15.

In the new study, rodents were trained to press a lever to receive a dose of cocaine.

In contrast, animals who had the nuclear form of HDAC5 did not press the lever nearly as often, even after the experimenters gave the animals a small priming dose of cocaine, which often produces strong drug - seeking behaviors.

With Simon Chen, another UC San Diego neurobiologist, the researchers monitored the activity of neurons in the motor cortex over a period of two weeks while mice learned to press a lever in a specific way with their front limbs to receive a reward.

The rats had to press the lever dozens of times before they were rewarded with a single sip, and each successive sip required two more presses than the previous one.

They found that pubescent rats would press the lever much more often than rats of any other age, putting in far more work for the calories they were getting, given their size.

Schneider and her colleagues trained their rats to press a lever in order to get a squirt of milk.

In subsequent experiments conducted by Olds, some rats pressed the lever as many as thousands of times an hour.

When they placed the electrode at a particular sweet spot, some rats pressed the lever hundreds of times an hour.

«If you consider these lever presses a measure of how much a rat will work to get a drug infusion, then these rats worked more than 10 times harder to get MDPV.»

In a head - to - head test of self - administration of alpha - PVP against MDPV, alpha - PVP showed an almost identical potency to induce lever presses.

«We observed that rats will press a lever more often to get a single infusion of MPDV than they will for meth, across a fairly wide dose range,» said TSRI Associate Professor Michael A. Taffe, who was the principal investigator of the study.

When the first rat pressed one of two levers, either right or left, an electrode in its cortex picked up a signal.

That animal, already trained to differentiate between the two types of pulses, pressed one lever or another depending upon the signal it received.

The animals learned that pressing one lever produced small but certain rewards in the form of small sugar pellets and an adjacent lever yielded bigger rewards — more pellets — but paid off less frequently.

This lever - pressing routine was associated with increased activity in the dorsolateral striatum, an area of the brain associated with habitual behaviors.

After five weeks of this treatment, the scientists trained all the rats to press levers — one lever delivered sweet sucrose pellets, and the other tasty grain.

Instead, they were pressing the lever out of habit.

They observed that an infusion of triglycerides in the brain reduces the animal's motivation to press a lever to obtain a food reward.

The scientists then changed the game, providing the rats with all of the snacks they wanted before giving them the option to press the lever.

Once I obtained aggressive behaviors in rats by stimulating specific areas of the brain, I started asking whether they liked or disliked the feelings by having them press a lever to turn the stimulation on or off.

The rats then underwent a period of abstinence with no audiovisual cue and no alcohol intake; regardless of how many times they pressed the lever.

When cells were inhibited, the mouse no longer pressed the lever, demonstrating that the activity of these cells was necessary for the mouse to carry out the behavior.

Inhibition of the neurons only caused this behavioral shift when the neurons were turned off at the time of feedback of results, when the rats found out if they pressed the rewarded lever.

For rats, that usually means pressing a lever to get an injection of cocaine.

Much like Pavlov's dogs, the rats immediately started pressing a cocaine - delivering lever in response, the researchers report in the 13 February issue of the Proceedings of the National Academy of Sciences.

Rats that have access to addictive substances such as cocaine, however, will continually press a lever to get more of the drug, even when it has been replaced by saline.

After many months of looking and listening for correlations between lots of different behaviors and cell activity, I began to realize that the major correlate was not what the animal was doing, whether it was eating or exploring an object or carrying out a simple tasks such as pressing a lever to get food, but something about where it was doing these things in the environment.

BAC HD mice, which typically reveal a less severe behavioral phenotype than the R6 / 2 line, did not show a deficit in the acquisition of a simple lever press.

Mice were reinforced for pressing one of two levers after a fixed amount of time (30 or 45 s) had elapsed from lever extension.

One strain of mouse, C57BL / 6J will seek the reward over and over, to the exclusion of food and sleep, another more slowly acquires the response, and may not continue to press the lever if the dose of drug is lowered, or the drug is no longer administered.

Some mice will continue to press the lever long after the drug stops coming, and some mice will start pressing the lever again as soon as they see a signal that they have learned to associate with drugs — think of driving through a neighborhood where a favorite bar is located.

Unique features include a Bench Press with «kick - assist» lever for complete prestretch and full range of motion, seat pads with automatic hydraulic adjustments, easy - access pop pin adjustments from the seated positions, and DuraFirm pads with lower lumbar support.

After five weeks, the scientists trained all of the rats to press levers.

Interestingly enough, the researchers found that the obsessive lever - pressing was associated with an area of the brain called the dorsolateral striatum — an area of the brain associated with habitual behaviors.

And, once you've been pressing the lever, for a dopamine rush of sugar (or fried foods, or alcohol), you're far more likely to press it again, and again.