Together, our results suggest that the decreased expression or loss of nuclear localization of DDX3 may play a regulatory role in the
formation of liver tumor and cutaneous SCC.
And in 2001, molecular biologist Mark Sands at Washington University in St. Louis, Missouri, found a high
rate of liver tumors in middle - aged mice that had been treated as newborns with a supposedly safer viral vector.
But this can not be taken as a very sharp indicator of hepatocellular carcinoma because serum levels of fetoprotein are usually elevated in other
types of liver tumors like bile duct carcinoma, lymphoma and non-neoplastic hepatic disease.
Researchers also have concerns that, while the silybin helps stimulate liver regeneration, it may also stimulate
growth of liver tumors, although research is not conclusive.
Chronic inflammation resulting from infections with hepatitis B virus (HBV) and hepatitis C virus (HCV) promote the
development of liver tumors.