One of the major next steps would be placing the engineered tissue in the vocal cords
of living animal models and having it survive and work.
Not exact matches
We are to
model our
lives after Christ, the Son
of God, who though he was God's very equal, came to earth, was born in an
animal's feeding stall and died on a cross.
What sorts
of mental
lives do
animals have, and how should we understand welfare?By presenting
models for understanding
animals» moral status and rights, and examining their mental
lives and welfare, David DeGrazia explores the implications for how we should treat
animals in connection wi...
It is currently playing out in the
live animal export sector, where the demise
of local processing opened the door for a
live export sector, which in turn through its simple business
model has compromised livestock welfare and alienated many consumers, reduced employment in Top End towns which once had abattoirs, and added risk to cattle business profitability by providing only one market outlet.
Animal Models of Early
Life Stress: Implications for Understanding Resilience.
«Hi Tor operates as a no - kill shelter and we are here to help all
animals survive and thrive, however we must be able to operate on a fiscally sound business
model or risk insolvency and the possibility
of putting these
animals lives at risk.
The search for more
of these factors is complicated by the rarity
of brain samples from suicide victims and the lack
of an
animal model — humans are unique in their wilful ability to end their
lives.
New experimental
models based on three - dimensional reconstructions
of human skin are helping to reduce chemical testing on
live animals, but can not yet replace
animals altogether
Scientists
of the German Center for Diabetes Research (DZD) led by the German Institute
of Human Nutrition (DIfE) have shown in a mouse
model that the epigenetic * modification
of the Igfbp2 ** gene observed in the young
animal precedes a fatty liver in the adult
animal later in
life.
Modeling how forces
of locomotion act on an
animal's bones —
living or extinct — could help scientists understand why.
Importantly, the development
of a new
animal model for Dravet syndrome based on reduced CHD2 expression might help to find effective treatments that could improve the
lives of thousands
of people suffering from Dravet syndrome and perhaps other genetic epilepsies.»
To better determine the role
of specific chemoattractants in type III hypersensitivity, lead author Yoshishige Miyabe, MD, PhD, a research fellow in Luster's lab, used multiphoton intravital microscopy — an imaging technology pioneered for studies
of immune cell movements in
living animals by CIID investigator and co-author Thorsten Mempel, MD, PhD — to follow in real time the development
of IC - induced arthritis in a mouse
model of rheumatoid arthritis.
The research showed that moral decisions in the con?ned scope
of unavoidable traffic collisions can be explained well, and
modeled, by a single value -
of -
life for every human,
animal, or inanimate object.
Using a novel approach for imaging the movement
of immune cells in
living animals, researchers from the Massachusetts General Hospital (MGH) Center for Immunology and Inflammatory Diseases (CIID) have identified what appear to be the initial steps leading to joint inflammation in a
model of inflammatory arthritis.
Scaling their
model up to a shark 21 feet long and weighing 7,300 pounds — akin to the largest
of living white sharks — they found that such an
animal opening its jaws to a 35 degree angle could squeeze its prey with almost 4,000 pounds
of force.
To tackle this problem, Patricia Lopes and her colleagues used a novel combination
of experimental manipulations
of free -
living mice, radio frequency tracking
of animals, social network analysis and disease
modelling.
The plant - gathering and hunting economy
of the San has been extensively studied as a
model for how people
lived until relatively recent times, when
animals and plants were domesticated.
The use
of cell surface markers to isolate specific cell populations is one common method for separating cells; however, isolating
live cells based on their RNA expression is a powerful new way enabling the study
of small cell niches in nongenetically modified
animal models and human tissue.
«I did a lot
of modelling to work out how far we needed to move the mine before detonating it — for the protection
of both the pipeline and the
animals that we know
live in that area.»
Historically,
animal models — from fruit flies to mice — have been the go - to technique to study the biological consequences
of aging, especially in tissues that can't be easily sampled from
living humans, like the brain.
New fossil evidence, computer
modeling and comparisons with
living creatures are helping scientists to paint a clearer picture
of these extinct
animals, overturning many historic conceptions
of their postures, gaits, skin coverings and colors.
But in
living choanoflagellates, King believes researchers have a
model organism to compare with
animals and dissect the roots
of animal multicellularity.
In a study published in the June 12 edition
of Science, they detail how a new drug repaired damage to the colon, liver and bone marrow in
animal models — even going so far as to save the
lives of mice who otherwise would have died in a bone marrow transplantation
model.
The first genetic clues for slowing aging emerged from
animal models in which the effect
of individual genes on average
life spans could be tested.
Researchers gave
animal models an oral supplement
of spermidine and found that they
lived longer and were less likely than untreated individuals to have liver fibrosis and cancerous liver tumors, even when predisposed for those conditions.
You can also learn about the real - world plant and
animal life that inspired Avatar's fictional flora and fauna, peer inside the Armored Mobility Platform suit that was used in combat scenes, and examine the filmmakers»
models of Na» vi characters and their costumes.
In order to understand the biology
of fossilized
animals, researchers often turn to
living animals with similarities that help
model how extinct
animals moved.
Using a mouse
model of fragile X syndrome, the researchers recorded the activity
of networks
of neurons in a
living mouse brain while the
animal was both awake and asleep.
Roundworms are a popular
animal model for longevity studies because
of their relatively short
life span and ease
of care.
And a variety
of studies with
animal models has shown that nanoparticles can trigger damage in
living tissues (Science, 18 June 2004, p. 1732).
«We wanted to develop a newborn screen for NPC because we know that the earlier we intervene with investigational treatments in
animal models of the disease, the longer the
animals live,» said Ory, the Alan A. and Edith L. Wolff Distinguished Professor
of Medicine.
The team, including researchers from the Natural History Museum in London, quantified the anatomical and genetic differences between
living animals, and established a timeframe over which those differences accumulated with the help
of the fossil record and intricate mathematical
models.
Instead
of using whole
animals, these
models used cells taken from
live animals and grown in Petri dishes.
Rieger used zebrafish larvae to
model peripheral neuropathy because the embryos develop rapidly and because the larval fish are translucent, making them ideal for studying the progression
of nerve degeneration in
live animals.
Kissler and his research team are using a mouse
model of type 1 diabetes to see what the genes do in a
living animal.
Current in vitro hematopoiesis
models fail to demonstrate the cellular diversity and complex functions
of living bone marrow; hence, most translational studies relevant to the hematologic system are conducted in
live animals.
Taking advantage
of fly genetics The research will combine the strength
of the fly system (
animals that are short
lived but complex enough to
model regenerative activity in vertebrates) with genetic studies in mice to understand the role
of mTOR signaling in maintaining the health
of adult stem cells in both species.
Over the last few years, scientists have been able to recreate accurate
models of human organs by embedding
living tissue onto chips, allowing them to study the effects
of drugs and diseases without testing on
animals or humans.
As part
of the SFI Investigators Programme 2016 call, SFI is providing applicants with the opportunity to seek funding to support the development and validation
of new tests,
models and approaches not involving the use
of live animals and / or addressing the principles
of the 3Rs (Replacement, Reduction and Refinement).
«The pRNA particles we constructed to harbor siRNA have a half
life of between five and 10 hours in
animal models, are non-toxic and produce no immune response,» says Guo [abstract].
After years
of experimenting with FMD in
animal models and showing its benefits on metabolism and
life span, Dr. Longo's team analyzed the effects in a human clinical trial that was published earlier this year.
In a study which takes us back to the previously described work
of Fenton Turck in 1916 [91, 92], a French group have recently reported that after one week
of a high - fat diet, prior to full onset type 2 diabetes (or the
animal model thereof),
live commensal bacteria are found in the blood and adipose tissue where they are associated with low - grade inflammation [93].
Spermidine both increases lifespan and healthspan in
animal models, and is enriched in the blood
of humans
living past 90.
This effect was also observed in a
live animal model, showing that rats injected with ar - tumerone into their brains experienced increases in neural stem cell proliferation and the creation
of newly formed healthy brain cells.
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Animals don't always make the best photography
models, as evidenced by the new holiday - themed teaser for «The Secret
Life of Pets.»
They might contribute to a biome poem, illustrate environmental pictures using sand art, make thermometers from used plastic bottles, construct a
life - sized
model of an igloo, enjoy snow cones from the tundra, or categorize
animals according to physical structures, adaptation abilities, and symmetry.
«The dog and cat industry has long served as a
model of how to provide support for
animals throughout all stages and challenges
of life,» says Lucas Stock, communications manager at Oxbow
Animal Health based in Omaha, Neb. «Knowledge and education regarding the longevity and specific health needs
of small
animals has evolved considerably in recent decades and across all sectors.»
Ultimately, it is up to parents or other significant role
models in a child's
life to guide them in the discovery
of what is a proper pet, how to handle, care and feed pets as well as the commitment made to an
animal we take into our custody... that it's for the
life of the pet....
The goal
of Code 597 will be to combat these images by showing positive role
models like Jarrod Cooper, # 40
of the Oakland Raiders and a dedicated Oakland
Animal Shelter volunteer, and providing resources to community members to improve the
lives of their
animals.