Sentences with phrase «of lobular»

The tempo and degree of lobular involution varies considerably among women, but the frequency and extent of involution increases with aging (68).

Not exact matches

The effects of estrogen and progesterone facilitate the formation of the characteristic structure of the adult breast, which is the terminal duct lobular unit.

Growth and development of the mammary tissues begins at around weeks three and four of gestation, with specific ductal branching and lobular formation.

In the first half of pregnancy secretory differentiation (the differentiation of alveolar epithelial cells into milk - secreting cells), ductal branching and lobular formation of the breast (mammogenesis) occur.

With that, investigators say the alterations in the ERBB2 gene strongly associate with pleomorphic lobular breast cancer but not the classic form of the disease.

Of 116 eligible breast cancers from The Cancer Genome Atlas, 86 were invasive lobular breast cancer.

Utilizing the invasive breast cancer data set of 962 cases in The Cancer Genome Atlas, all breast cancers with alterations in the CDH1 gene (that gives instructions to make a protein that causes cancer cells to stick to one another and defines lobular breast cancers) were identified.

PELOPS: Palbociclib and Endocrine Therapy for Lobular Breast Cancer Preoperative Study: A Randomized Phase II Study of Palbociclib with Endocrine Therapy versus Endocrine Therapy Alone for Invasive Lobular Carcinoma and Invasive Ductal Carcinoma

Dr. Jos Jonkers» research group studies the genetic basis of human breast cancer, using advanced mouse models for p53 - induced breast cancer, BRCA1 - and BRCA2 - associated hereditary breast cancer, and E-cadherin mutated invasive lobular carcinoma.

Tobin NP, Lundgren KL, Conway C, Anagnostaki L, Costello S. Automated image analysis of Cyclin D1 protein expression in invasive lobular breast carcinoma provides independent prognostic information.

Lobular carcinoma in situ, or LCIS, is not a cancer, but an overgrowth of cells that occurs in the milk - producing lobules.

Invasive lobular carcinoma, or ILC, is an uncommon type of breast cancer that begins in the milk - producing lobule cells and invades (spreads) deeper into the breast tissue.

Invasive lobular carcinoma (ILC) is the second most common breast cancer subtype and accounts for 8 - 14 % of all cases.

But when her doctor told her that the type of tumor she had — invasive lobular carcinoma — slightly increased her risk of developing cancer in the unaffected breast, she decided to have a double mastectomy and sacrifice her ability to breast - feed.

Also known as «infiltrating lobular carcinoma,» ILC can spread beyond the lobules into surrounding breast tissue and metastasize to other parts of the body.

Women are generally in this group if they have multiple cases of breast or ovarian cancer in the family, a positive result on the BRCA breast cancer gene - mutation test, a personal history of the disease, or a biopsy showing atypia or lobular carcinoma in situ.

It is also important to note that inflammatory breast cancer is much more aggressive than the other types of invasive breast cancers we have discussed, including both invasive ductal carcinoma and invasive lobular carcinoma.

While ductal carcinoma in situ develops in the duct's lining of the breasts, lobular carcinoma in situ develops in the lobules — the parts of the breast tissue that is responsible for the production of milk.

The lobular composition of the breast of sexually mature women is influenced by numerous endogenous and exogenous factors.

Inflammatory breast cancer is more likely to be HER2 + than ductal or lobular breast cancer, the most common types of invasive breast cancer.

Methods: We combined data from two population - based case - control studies to examine the relationship between migraine and risk of postmenopausal invasive breast cancer among 1,199 ductal carcinoma cases, 739 lobular carcinoma cases, and 1,474 controls 55 to 79 years of age.

Results: Women who reported a clinical diagnosis of migraine had reduced risks of ductal carcinoma (OR, 0.67; 95 % CI, 0.54 - 0.82) and lobular carcinoma (OR, 0.68; 95 % CI, 0.52 - 0.90).

Selected characteristics of controls, invasive ductal carcinoma cases, and invasive lobular carcinoma cases

These include growths arising from the epithelium that normally produces milk (lobular or epithelial hyperplasia, occasionally called adenosis), growths that also include the connective tissue between the glands (fibroadenomatous change or fibroepithelial hyperplasia), and growths due to expansion of the ducts which take the milk to the teats (cystic ducts, ductal ectasia or hyperplasia).

They include those arising from the epithelium that normally produces milk (lobular or epithelial hyperplasia, occasionally called adenosis), growth that also include the connective tissue between the glands (fibroadenomatous change or fibroepithelial hyperplasia) and growths due to expansion of the ducts that take the milk to the teats (cystic ducts, ductal ectasia or hyperplasia).

The malignant form of primary liver cancer either forms a single lobular mass on the organ or may cause multi nodular masses, which are more complicated in nature and which can spread rapidly to other parts of body, especially brain directly through the hepatic portal vein.