Sentences with phrase «of lung injury»

Proteomic analysis discovers signatures of consecutive phases of lung injury, fibrosis, and repair.

To date, the regenerative mechanisms leading to healing of lung injury remain incompletely understood.

In the aftermath of 9/11, New York City fire department rescue and recovery workers exposed to the caustic dust at the site experienced high rates of lung injury and excessive loss of lung function.

The report mentioned that the gene could even «shed light on the causes of lung injuries» but turned out they were talking about «injuries» like pneumonia, inflammation or pulmonary fibrosis.

Not exact matches

While this process causes some lung injury, most of the symptoms of the flu are actually caused by the immune response to the virus.

One flavonoid in lemongrass called luteolin has such strong anti-inflammatory abilities that it may be able to treat some symptoms of multiple sclerosis, as well as lung infections or acute lung injury.

Elneny has the lung capacity of a Kenyan long distance athlete, covering more ground, and with less injury timeout.

You shouldn't ignore the persistent hiccups in your child, since this can be a symptom of brain damage; various diseases of the stomach, liver or lungs; injuries of the spinal cord and the chest.

This would impact a range of funding areas, including research on kidney and lung disorders, digestive diseases, central nervous system injuries, and sensory loss.

They discovered that in the young, more immune cells called monocytes were recruited to the lungs, and that the gene expression profiles of these cells had more inflammatory features, causing greater inflammation and more severe lung injury.

The scientists conclude that in mice «well - timed treatment with rIL - 27 improved lung injury and accelerated recovery without affecting viral clearance» and continue «these data demonstrate that IL - 27 has a unique role in controlling immunopathology without impacting on host defense, and might therefore represent a promising candidate for immunomodulatory therapy of viral pneumonia.»

Unattached Gruesomely nicknamed internal decapitation, this kind of injury often kills by severing the spine, impeding signals sent by the brain that tell the lungs to breathe from reaching their destination.

The discussion also covers the management of common long - term complications such as heterotopic ossification, in which solid masses of bone begin growing inappropriately within soft tissues near blast injury sites, and the formation of blood clots in the extremities and lungs, which occurs at a high rate in DCBI survivors.

Radovitzky says this reasoning stems from studies of «blast lung» — blast - induced injuries such as tearing, hemorrhaging, and swelling of the lungs, where it was found that mass matters: The larger an animal is, the more resilient it may be to lung damage.

While the autopsy showed low levels of carbon monoxide in the woman's blood, it also revealed extensive thermal injuries in her air passages and lungs.

Zhang, a member of Ohio State's Davis Heart and Lung Research Institute, is particularly interested in bioadhesives that could aid in wound healing after injury or surgeries.

Crouch and his colleagues found that those in the low PVR group had lower mortality (0 vs. 1.1 %) and fewer complications, including delirium (7.8 % vs. 14.9 %), pneumonia / tracheobronchitis (6.3 % vs. 15.5 %), and a statistically significant lower rate of reperfusion lung injury (7.8 % vs. 25.9 %), The low PVR group also experienced statistically significant recoveries, with less time spent on the ventilator (1.7 vs. 3.2 days), in the ICU (4 vs. 5.8 days) and in the hospital (13 vs. 16.3 days).

By triggering a process called autophagy — in which cells literally engulf their own insides — researchers from Drexel University and Yale University were able to decrease lung injury in mice that were exposed to high concentrations of oxygen.

If this type of therapy proves safe in humans, a syringe full of oxygen microbubbles could help avert brain damage and death for the victims of cardiac arrest, asthma attacks, strokes, and injuries to the lungs, airway, or face.

Acute lung injury develops as a result of direct or indirect trauma to the lungs.

WASHINGTON — Paralyzed rats can breathe a sigh of relief: A new treatment can restore lung function, even a year and a half after a spinal cord injury that takes it away.

Further, in laboratory mice, the team found that by deleting this substance, they could produce the type of scarring found in pulmonary fibrosis after lung injury.

The worst chlorine gas accident in the country occurred in 2005, when 18 freight train cars derailed and released 120,000 pounds of chlorine gas in the mill town of Graniteville, S.C. Nine people were killed and at least 1,400 people were exposed, resulting in more than 550 people treated at hospitals, including some with serious lung injuries.

Researchers at Johns Hopkins University checked in with survivors of a lifethreatening lung injury for two years after they were discharged from the ICU.

An experimental drug has shown promise in treating influenza, preventing lung injury and death from the virus in preclinical studies, according to University of Maryland School of Medicine researchers publishing in the journal Nature on May 1.

Previous scientific studies have revealed that acute lung injury caused by the influenza virus is the result of an immune reaction mediated by a protein called Toll - like receptor 4 (TLR4).

Two studies published in the January issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists ® (ASA ®), shed new light on the prevalence of transfusion - related acute lung injury (TRALI) and transfusion - associated circulatory overload (TACO), the number one and two leading causes of blood transfusion - related deaths in the United States.

Original publication: Schiller, HB et al. (2015) Time - and compartment - resolved proteome profiling of the extracellular niche in lung injury and repair, Molecular Systems Biology, DOI:: 10.15252 / msb.20156123 Link to the publication

Fourth, the finding of intranuclear inclusions in diseased tissues, as well as direct visualization of adenoviral - like particles (TMAdV) in lung alveoli by electron microscopy (Figs. 1D - 2 to 1D - 4), support a primary role for TMAdV in the pathogenesis of tissue injury in affected monkeys.

The primary outcome is in - hospital mortality, and secondary outcomes include the complications of BSI such as septic shock, acute kidney injury (AKI), acute lung injury (ALI) / acute respiratory distress syndrome (ARDS), disseminated intravascular coagulation (DIC), ischemic liver injury, and a collapsed dependent variable of «poor clinical outcome» that is defined as the presence of any of the above complications.

Naringenin ameliorates LPS - induced acute lung injury through its anti-oxidative and anti-inflammatory activity and by inhibition of the PI3K / AKT pathway.

Soluble CD40 ligand accumulates in stored blood components, primes neutrophils through CD40, and is a potential cofactor in the development of transfusion - related acute lung injury.

Impact of bone marrow - derived mesenchymal stem cells on remodeling the lung injury induced by lipopolysaccharides in mice Mouchira M Mohi El - Din, Laila A Rashed, Mohi A Mahmoud Haridy, Atef Mohamed Khalil, Mohamed A Mohamed Albadry.

The use of technetium - 99m hexamethylpropylene amine oxime lung scintigraphy in the detection of subclinical lung injury in patients with noninsulin - dependent diabetes mellitus.

Pre-clinical evidence concerning the utility of mesenchymal stem cells (MSCs) to aid the treatment of acute lung injury (ALI) has been mounting over recent years, with some clinical trials beginning to run.

Conclusions: CGRP stimulates the expression of multiple molecules in the Wnt 7b / β - catenin pathway in AEC II under hyperoxia, which might be part of the mechanism by which CGRP protects the lung from hyperoxia - induced injury.

The role of integrin [alpha] 8 [beta] 1 in fetal lung morphogenesis and injury.

Elevated expression of hexokinase II protects human lung epithelial - like A549 cells against oxidative injury.

Kenneth R. Cooke, M.D. University of Michigan Medical School Acute lung injury after SCT: from laboratory insights to novel strategies for diagnosis and treatment

Since we observed robust inhibition of NFκB in the presence of RIPK2 inhibitor 1 and a > 70 % recovery of animals from DSS - induced inflammation injury (Figs. 4 and 6B), we proceeded to explore the ability to resolve lung inflammation using the ovalbumin challenge model (Kumar et al., 2008).

Research should help various agencies to reach recommendations and actions on the issue of drug use and lung injury.

Examples include a series of studies to document persistent microchimerism of donor cells in transfusion recipients, with particular focus on mechanisms and clinical relevance of donor stem cell microchimerism in transfused trauma patients, and the immunological mechanisms and prevention of transfusion - related acute lung injury (TRALI) and alloimmunization.

Using translational research methods, the DZL seeks to jointly develop new approaches for the prevention, diagnosis and therapy of serious lung diseases including asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, diffuse parenchymal lung disease (DPLD), endstage lung disease, lung cancer, pneumonia and acute lung injury, and pulmonary hypertension.

In the elderly, lung injury from inhaled particles or from infections might lead to undue scarring processes, some of which in turn lead to lung fibrosis and respiratory insufficiency.

Calcitonin gene - related peptide (CGRP) has been shown to improve survival of lung epithelial cells and reduce hyperoxic lung injury in rats.

Calcitonin Gene - Related Peptide Enhances the Expression of Signaling Molecules of the Wnt 7b / Beta - Catenin Pathway in Rat Type II Alveolar Epithelial Cells Under Hyperoxia Hyperoxic lung injury is characterized by epithelial cell death and leukocyte infiltration / inflammation in the lung.

Time and compartment ‐ resolved proteome profiling of the extracellular niche in lung injury and repair

The HARP study showed that 80 mg of simvastatin administered acutely to patients with acute lung injury showed significant improvements in organ failure scores, suggesting that statins modulate the systemic inflammation after only a short duration of treatment [17].

We often treat people who have fallen off of high ladders, which results in serious and extensive injuries (head trauma, collapsed lungs).

But her lower limbs were not the extent of her injuries, which also included a broken sternum, ribs, and pelvis, in addition to bruising to her heart and lungs, Global News reported.