Sentences with phrase «of lupus patients»

As rheumatologist taking care of lupus patients I try to cover all areas of well being — not just the physical part.

About 90 % of lupus patients are women, mostly in their childbearing years, and many of them experience more symptoms of lupus in pregnancy or before their menstrual periods.

About 40 percent of lupus patients develop lupus nephritis, impairing their ability to effectively shed waste products and other toxins.

While this condition doesn't affect all lupus sufferers, an estimated 40 percent of lupus patients develop it.

However, much can be done to improve quality of life of the lupus patient.

Not exact matches

All patients had an established history of systemic lupus erythematosus (SLE), and either a history of CNS lupus or active CNS lupus.

Drug - induced lupus occurs when a patient has a reaction to certain types of medication, but it usually goes away once the person stops taking the medicine.

The amended legislation would cap the number of organizations providing marijuana to patients at 20, and eliminated a number of illnesses eligible for the program including lupus and diabetes.

«We also confirmed that human patients with a missing or malfunctioning DNASE1L3 gene had an abundance of circulating DNA and developed antibodies to it, and that such antibodies were also present in most forms of lupus,» says Reizis.

About half of patients also have RA or other connective tissue diseases, such as lupus.

«Lupus is a heterogeneous disease and patients can experi.ence a number of different symptoms.

The development shows that for the first time, it is feasible for researchers to identify the individual causes of lupus in patients by using DNA sequencing, allowing doctors to target specific treatments to individual patients.

An encounter with a lupus patient crystallized one scientist's concept of «translational research» and fundamentally changed the focus of her lab.

«Given that only one new drug has been approved for lupus patients in the last 50 years, there is a pressing need for more specific and less toxic drugs to treat it and other autoimmune disorders,» says Means, who is an assistant professor of Medicine at Harvard Medical School.

With only one drug specifically approved for the treatment of lupus in the past 50 years, lupus patients are commonly treated with steroids, a class of immunosuppressive drugs that delay the development and progression of the disease by suppressing the immune system.

Animal studies have suggested that overactivation of TLR7 plays a role in lupus, and a gene variant that increases expression of the receptor has been associated with increased lupus risk in human patients.

Gulati offers some suggestions for Lupus patients to lessen some of the environmental factors that can trigger Lupus symptoms.

The researchers also noted that the region of the X chromosome containing Xist showed the biggest differences in expression when comparing lupus to healthy patients.

To build on the work, Anguera's team is performing additional studies using primary samples from lupus patients as well as samples from a mouse model of lupus.

Study enrollment of patients with and without lupus was supported by ResearchMatch, a service provided through the support of the Ohio State University Center for Clinical and Translational Science.

Margaret Shupnik, PhD, a Professor of Medicine at UVA's School of Medicine who also worked with Jarjour's team says she hopes that the findings will prompt other researchers to develop novel therapies that regulate TLRs, and offer lupus patients the kind of treatment options that they currently don't have.

The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2016) showed for the first time an association between a specific genetic pathway and the development of mouth ulcers in patients with Systemic Lupus Erythematosus (SLE).

This discovery, details of which have been published in the Proceedings of the National Academy of Sciences (PNAS), opens the door to new ways to treat patients with septic shock caused by viral or bacterial infection as well as people with auto - immune diseases like rheumatoid arthritis and lupus.

A first group consisted of patients with lupus, a systemic chronic rheumatic disease.

The next step, Datta says, is to find which fragments of the human histones trigger lupus, then test whether injecting high doses in patients will help them.

«One in six lupus patients readmitted to hospital within 30 days of discharge.»

The team analyzed data of 31,903 lupus patients readmitted between 2008 and 2009 from 5 states — California, Florida, New York, Utah and Washington.

«In general, lupus patients commonly have a broad range of neuropsychiatric symptoms, including anxiety, depression, headaches, seizures, even psychosis,» says Allison Bialas, PhD, first author on the study and a research fellow working in the lab of Michael Carroll, PhD, senior author on the study, who are part of the Boston Children's Program in Cellular and Molecular Medicine.

Clinical features most associated with readmission included patients with lupus nephritis (kidney inflammation), serositis (inflammation of the lining of the lungs, heart, abdomen, or abdominal organs) and thrombocytopenia (low blood platelet count).

Lupus patients make too much type I interferon, which boosts production of the self - attacking antibodies that cause symptoms.

His group is planning to launch a trial of the drug, which has been approved for use in people for more than a decade, in lupus patients.

Up to 75 percent of patients with systemic lupus erythematosus — an incurable autoimmune disease commonly known as lupus — experience neuropsychiatric symptoms.

Of special note today: gut microbiota species expressing orthologs of human Ro60 might be involved in triggering and sustaining chronic autoimmunity in lupus; The portal vein blood microbiome in patients with liver cirrhosis; A randomized clinical study suggests dietary promotion of short chain fatty acid producing gut microbes as an effective treatment for type 2 diabetes; and the sexual dimorphism of root, flower and leaf microbiomes in the wild strawberry plaOf special note today: gut microbiota species expressing orthologs of human Ro60 might be involved in triggering and sustaining chronic autoimmunity in lupus; The portal vein blood microbiome in patients with liver cirrhosis; A randomized clinical study suggests dietary promotion of short chain fatty acid producing gut microbes as an effective treatment for type 2 diabetes; and the sexual dimorphism of root, flower and leaf microbiomes in the wild strawberry plaof human Ro60 might be involved in triggering and sustaining chronic autoimmunity in lupus; The portal vein blood microbiome in patients with liver cirrhosis; A randomized clinical study suggests dietary promotion of short chain fatty acid producing gut microbes as an effective treatment for type 2 diabetes; and the sexual dimorphism of root, flower and leaf microbiomes in the wild strawberry plaof short chain fatty acid producing gut microbes as an effective treatment for type 2 diabetes; and the sexual dimorphism of root, flower and leaf microbiomes in the wild strawberry plaof root, flower and leaf microbiomes in the wild strawberry plant

A study based on medical records from more than a quarter million adult patients found that African - American patients with connective tissue diseases such as lupus or rheumatoid arthritis were twice as likely as white patients to suffer from narrowed or atherosclerotic blood vessels, which increase the risk of a heart attack, stroke or death.

February 4, 2016 Connective tissue disease increases risk for cardiovascular problems A study based on medical records from more than a quarter million adult patients found that African - American patients with connective tissue diseases such as lupus or rheumatoid arthritis were twice as likely as white patients to suffer from narrowed or atherosclerotic blood vessels, which increase the risk of a heart attack, stroke or death.

Last year the Food and Drug Administration approved Benlysta (belimumab), the first new treatment for systemic lupus erythematosus in more than 50 years, and Yervoy (ipilimumab), the first drug shown to prolong the lives of patients with melanoma.

When he tallied up patients with connective tissue disease — such as rheumatoid arthritis, lupus, scleroderma or dermatomyositis — there was a clear connection between CTD and increased risk of atherosclerotic cardiovascular disease.

CXCR4 is significantly up - regulated in monocytes, neutrophils, and B - cells from murine models of lupus [53] as well as patients with SLE [51].

And a third clue emerged from their studies: One strain of the knockout mice showed sensitivity to sunlight — a characteristic of human lupus patients that produce antibodies against the Ro protein.

Closer study of the Ro - knockout mice revealed that they had kidney lesions similar to those observed in patients with lupus.

We offer a program focused on the treatment of pediatric hypertension, as well as a combined program with our rheumatology colleagues for the treatment of patients with systemic lupus erythematosus (a chronic, inflammatory autoimmune disorder) and other combined kidney / rheumatologic conditions.

Patients had blood tests to rule out common causes of severe fatigue such as anemia, liver disease, hypothyroidism, systemic lupus erythematosus, and Lyme disease [14].

About 90 % of people with the autoimmune disease lupus have joint pain, and more than half of patients say it was one of the first symptoms they experienced.

Also, not all Lupus patients have the same severity of the disease.»

Lupus patients at risk of blood clots may be given low - dose aspirin or prescription warfarin or heparin.

Exposure to sunlight or other sources of ultraviolet light (even artificial) can worsen a lupus patient's butterfly rash.

As many as one in three lupus patients with the most common form of the disease (systemic lupus erythematosus, or SLE) develop a condition called Raynaud's disease.

However, there are a few telltale signs, especially in lupus patients who develop skin symptoms or have the form of lupus that only affects the skin, called cutaneous lupus erythematosus.

Lupus patients are also prone to cardiodegenerative symptoms including anemia, high blood pressure, heart disease, shortness of breath, seizures and stroke.

7 Suzuki T, Suzuki N, Engleman EG, Mizushima Y and Sakane T. Low serum levels of dehydroepiandrosterone may cause deficient IL - 2 production by lymphocytes in patients with systemic lupus erythematosus (SLE).