At the present time, the lab values do not support a diagnosis of hypothyroidism for your dog but they do support a diagnosis
of lymphocytic thyroiditis, which may eventually lead to hypothyroidism.
The newer tests for antithyroglobulin antibodies (thyroglobulin autoantibodies) is a pretty good indicator of the presences
of lymphocytic thyroiditis.
Not exact matches
On the other hand, iodine may be one
of the potential culprits in the dramatic surge in diagnoses
of Hashimoto's
thyroiditis, also known as autoimmune
thyroiditis or chronic
lymphocytic thyroiditis, which has occurred in recent years.
It can also be used to suppress or treat some types
of goiters like chronic or sub acute
lymphocytic thyroiditis or otherwise known as Hashimoto's disease, multinodular kind
of goiter, thyroid nodules and management
of thyroid cancer.
Hashimoto's
thyroiditis is an inflammation
of the thyroid gland and sometimes referred to as Hashimoto's disease, chronic
lymphocytic thyroiditis and autoimmune
thyroiditis.
The tumors cause hyperthyroidism in 10 %
of cases which is caused by
lymphocytic thyroiditis (inflammation).
In the dog, hypothyroidism is usually caused by one
of two diseases:
lymphocytic thyroiditis or idiopathic thyroid gland atrophy.
Roughly half
of these cases occur due an autoimmune disease
of the thyroid gland (termed
lymphocytic thyroiditis).
Dr. Lorna Kennedy at the University
of Manchester's Centre for Integrated Genomic Medical Research in England has found the haplotype (group
of genes), which, when present, double the chances
of a Ridgeback becoming hypothyroid due to
lymphocytic thyroiditis.
In cases
of autoimmune thyroid gland disease (
lymphocytic thyroiditis), special blood tests may be sent to a specialty lab to measure levels
of abnormal antibodies (antithyroglobulin antibody or autoantibodies to T3 and T4).
Most cases
of canine hypothyroidism appear to be caused by infiltrating cells from the immune system — lymphocytes that enter the thyroid gland in a condition called
lymphocytic thyroiditis or autoimmune
thyroiditis (Graham et al., 2001).
Autoimmune
thyroiditis (also called
lymphocytic thyroiditis) is the most common cause
of primary hypothyroidism in dogs and is known to be an inherited disease.
Lymphocytic thyroiditis, probably immune - mediated, is characterized histologically by a diffuse infiltration
of the gland by lymphocytes, plasma cells, and macrophages and results in progressive destruction
of follicles and secondary fibrosis.
The two most common causes
of adult - onset primary hypothyroidism in dogs include
lymphocytic thyroiditis and idiopathic atrophy
of the thyroid gland.