When injected into mice that were then given a subsequent
injection of lymphoma cells, the 3D vaccine generated a potent immune response and delayed tumor growth.
Their innovative approach consists in using an antibody able to neutralize a specific protein to block the
migration of lymphoma cells, thus preventing the disease from developing.
Like a free pass, its presence on the
surface of lymphoma cells facilitates their migration through the vessel walls between adjacent endothelial cells.