This effect may be directly related to the role played by Themis1 in TCR signaling in effector T cells or to a secondary effect
of lymphopenia induced by Themis1 deficiency.
Not exact matches
The most common adverse side effects were
lymphopenia (a condition
of abnormally low levels
of white blood cells called lymphocytes), neutropenia, blood platelet deficiency, and infection.
Developing a human recombinant IL - 7 for the treatment
of diseases that are caused by
lymphopenia.
Some clinical studies
of human patients have indicated that
lymphopenia and elevated liver enzyme values are associated with Lyme disease [49, 50].
We demonstrate a novel outcome
of S1P - mediated regulation
of lymphocyte trafficking, whereby deletion
of Spns2, either globally or in a lymphatic endothelial - specific manner, creates a circulating
lymphopenia and a higher percentage
of effector T cells and natural killer (NK) cells present in the lung.
In animals and humans, zinc deficiency results in rapid and marked atrophy
of the thymus, impaired cell - mediated cutaneous sensitivity and
lymphopenia.
These may reveal a reduced number
of lymphocytes (white blood cells that function in the immune system), a disease called «
lymphopenia».
Finding that white blood cells are very low (
lymphopenia) suggests a diagnosis
of distemper, but
lymphopenia also occurs with parvovirus infection.
Less reliably low numbers (
lymphopenia) occurs early in parvovirus infection in dogs and in panleukopenia
of cats or after prolonged periods
of stress.