Sentences with phrase «of macrocyclic lactones»

Selamectin, part of the macrocyclic lactones group is considered safe in dogs and has low or no adverse effects in Ivermectin — sensitive dogs.

Selamectin is considered the safest option of the macrocyclic lactones; which can be administered 6mg / Kg BW, orally in single doses and repeated in one - month in intervals.

Discontinue the use of macrocyclic lactones as a «slow kill» protocol for known heartworm infections; it is NOT recommended by the American Heartworm Society.

Use microfilaricidal doses of macrocyclic lactones to reduce transmission from pets receiving adulticidal treatment.

More commonly, microfilariae are eventually eliminated, even from non-adulticide-treated dogs, after several months of treatment with prophylactic doses of the macrocyclic lactones.

Efficacy of macrocyclic lactones decreases below 100 % in dogs, however, if first administered > 2 months after exposure to infective larvae.

Not exact matches

Macrocyclic lactones do not readily cross the mature mammalian blood - brain barrier.17 Safety in mammals is due to the lack of glutamate-gated chloride channels in the peripheral nervous system and the restriction of GABA to the central nervous system.

Table 5: Macrocyclic Lactone Dosages for Generalized Demodicosis in Dogs The ease of oral administration compared with dips makes macrocyclic lactones the first line of therapy for many dermatologistsMacrocyclic Lactone Dosages for Generalized Demodicosis in Dogs The ease of oral administration compared with dips makes macrocyclic lactones the first line of therapy for many dermatologistsmacrocyclic lactones the first line of therapy for many dermatologists (Table 5).

[Several] products contain macrocyclic lactones which kill the tissue stages of heartworm larvae and are given once a month.

a. Administer macrocyclic lactone preventive drugs to dogs greater than 6 weeks of age prior to relocation.1

A single dose of topical moxidectin prior to transport will eliminate most microfilariae.4 - 6 OR Administer an approved macrocyclic lactone product along with a topical canine insecticide (containing permethrin + dinotefuran + pyriproxyfen) that is labelled to kill and repel mosquitoes.

The new text on the CAPC website states: «Recent work has shown that there are isolates of heartworms that are capable of developing to adults in dogs receiving routine prophylaxis with any of the available macrocyclic lactones.»

A passage in the CAPC guidelines written in capital letters practically shouts the importance of using approved «adulticide» products to treat heartworm infected dogs rather than the «slow - kill» method of using macrocyclic lactone preventives to gradually treat an adult heartworm infection.

Anecdotal evidence and preliminary scientific studies suggest that some populations of heartworms may behave differently when exposed to macrocyclic lactones.

In recent years veterinarians have made greater use of a group of chemicals known as macrocyclic lactones.

The new data shows that blocking transmission from dogs to mosquitoes, and from mosquitoes to dogs, using repellents / insecticides and macrocyclic lactone preventives is part of a multi-modal approach.

When definitive adulticidal therapy with melarsomine can not be provided immediately, heartworm - positive dogs should be started on a 4 - week course of doxycycline and a monthly preventive with a macrocyclic lactone until such treatment can be provided.

American Heartworm Society guidelines recommend «doxycycline and a macrocyclic lactone prior to the three - dose regimen of melarsomine... for treatment of heartworm disease in both symptomatic and asymptomatic dogs.

Unlike dogs, heartworm - positive cats are at very low risk of developing adverse reactions from macrocyclic lactones.

Administering doxycycline and a macrocyclic lactone during the 1 - month rest period after melarsomine administration eliminates most of the remaining circulating microfilariae, and any remaining adult worms are essentially sterile and die of attrition over time.

Citing the need to better understand critical issues such as macrocyclic lactone resistance to heartworm preventives and the role of the immune system in heartworm prevention, the American Heartworm Society (AHS) has announced that it is accepting proposals for new heartworm research studies.

A Complete Interactive Continuing Education Program on Heartworm Disease - Hear the latest information on controversial topics such as «slow kill» and macrocyclic lactone lack of efficacy investigations.

In the study they had four groups: a control group, the topical product only group, a macrocyclic lactone - only group, and a macrocyclic lactone with the topical product group, and the latter was the only group where there was no development of adult heartworms.