Sentences with phrase «of macrolide»

Spinosad is a derivative of macrolide antibiotics Spinosad attacks the nervous system of the flea acting on the nicotinic acetylcholine receptors, there is no interaction with other insecticides.

Designer macrolide biosensors should find broad utility and enable applications related to high throughput synthetic biology and directed evolution of macrolide biosynthesis.

In E. coli, MphR can detect the presence of macrolide antibiotics being secreted by microbes that are attacking E. coli.

The use of macrolides during the first two years of life was associated with increased body mass index.

The use of macrolides was associated with microbiota features, which have previously been associated with obesity and metabolic diseases.

Heavy use of macrolides in the first two years of life was also associated with an increased risk of asthma later in life.

They then plated large numbers of E. coli onto a medium that contained one of several antibiotics, including from the classes of macrolides,?

But, current use of macrolides was associated with an additional 118 ventricular tachyarrhythmias or related sudden cardiac deaths per 1 million treatment courses.

Not exact matches

Strains of S. pyogenes resistant to macrolide antibiotics have emerged, however all strains remain uniformly sensitive to penicillin.

Researchers are interested in using these natural antibiotics and the microbes that produce them in order to develop new antibiotics; however, microbes that produce antibiotic macrolides only make small amounts of a limited variety of antibiotics.

The researchers created a large library of MphR protein variants and screened them for the ability to switch on production of a fluorescent green protein when they were in the presence of a desired macrolide.

Macrolides appear also to contribute to the development of antibiotic - resistant strains of bacteria.

The results support the recommendation to avoid macrolides as the primary antibiotic, and generally restrict the use of antibiotics to genuine need.

To help on this front, in a new paper published in the journal Structure, researchers from McGill University present in atomic detail how specific bacterial enzymes, known as kinases, confer resistance to macrolide antibiotics, a widely used class of antibiotics and an alternative medication for patients with penicillin allergies.

Particularly the microbiota of the children who had received macrolide antibiotics, such as azithromycin or clarithromycin, within the past two years differed from normal.

As a result, almost three more years were required to figure out how the different parts of the kinase confer resistance to different macrolide antibiotics.

«Penicillin - type antibiotics seemed to have a weaker impact on the composition and functioning of the microbiome than macrolides,» Korpela says.

Macrolides appear to promote also the development of antibiotic resistance, as the resistance to these antibiotics was elevated in the microbiota of children who had used them.

We identified variants that displayed improved sensitivity towards erythromycin, tailored the inducer specificity, and significantly improved sensitivity to macrolides that were very poor inducers of the wild - type MphR biosensor.

The results revealed a small, but statistically significant, association between taking macrolides and increased risk of sudden cardiac death.

An average of 80 cases of rapid heartbeat that can result in sudden cardiac death (or «ventricular tachyarrhythmias») occurred per 1 million treatment courses among patients who were not taking macrolides, the investigators found.

To put the findings into perspective, one in 8,500 patients treated with macrolides could develop a serious heart rhythm problem and one in 30,000 might die, Dr. Sami Viskin, from the Tel Aviv Medical Center and Sackler School of Medicine at Tel Aviv University in Israel, explained in an accompanying journal editorial.

The studies compared patients who took macrolides, other types of antibiotics, or no antibiotics.

CsA is a derivative of the fungus Tolypocladium inflatum whereas tacrolimus is a macrolide antibiotic produced by Streptomyces tsukubaensis.

There are 21 classes of antibacterial drugs, with fluoroquinolones and three others — penicillins, macrolides, and cephalosporins — accounting for approximately 80 percent of all antibacterial prescriptions and sales.