Not exact matches
«One
of the
major limitations in developing a corrective
gene therapy is that it will treat
only a single disease,» said Sudharsan.
Not
only did a high percentage
of embryonic cells get repaired, but also
gene correction didn't induce any detectable off - target mutations and genome instability —
major concerns for
gene editing.
The
only plausible methods
of repairing stochastic nuclear DNA damage look to be the aforementioned advanced molecular nanotechnology, something that lies some decades in the future, or
major advances in
gene therapy, to the point at which it could be cost - effective and safe to scan and conditionally alter the majority
of genes in the majority
of cells all at once.
However, Boule homologs have been maintained throughout all
major lineages
of animals from a common eumetazoan ancestral
gene and are required
only for sperm development in both Drosophila and mice.