A common intestinal parasite is Giardia lamblia (also known as Giardia intestinalis), a protozoan that uses a «sucker» to adhere to the intestines
of mammalian hosts, including humans.
OspC expression is required for B. burgdorferi infection
of mammalian hosts.
The studies also allowed the team to pinpoint patterns of evolutionary change in the genes of these viruses, reflecting their adaptation to different kinds
of mammalian hosts.
B. burgdorferi possesses one protein that is essential for establishing a long - term infection
of a mammalian host: VlsE.
Anaplasma phagocytophilum Outer Membrane Protein A Interacts with Sialylated Glycoproteins To Promote Infection
of Mammalian Host Cells
Not exact matches
In addition, changes in the microbial ecology
of the
mammalian digestive tract can harm the health
of the
host.
Following introduction into
mammalian hosts (including humans) by the bite
of a sand fly, Leishmania parasites undergo extensive changes to adapt to survival and multiplication inside the new
host cells and tissues.
We used a mathematical model
of within -
host virus evolution to study factors that could increase and decrease the probability
of the remaining substitutions evolving after the virus has infected a
mammalian host.
The Nature study, titled «Acoustic reporter genes for noninvasive imaging
of microbes in
mammalian hosts,» was funded by the National Institutes
of Health, the Canadian Institute
of Health Research, the Burroughs Wellcome Fund, the Packard Fellowship, the Pew Scholarship, the Heritage Medical Research Institute, the National Science Foundation, and the Natural Sciences and Engineering Research Council
of Canada.
The majority
of the positive samples (72 percent) were 79 - 100 percent similar to astroviruses associated with human infections; 23.5 percent
of the samples were similar to
mammalian astroviruses isolated from diverse animal
hosts including dogs, pigs and sheep.
Genome sequence alterations detected upon passage
of Burkholderia mallei ATCC 23344 in culture and in
mammalian hosts.
The discovery eventually led to the uncovering by others
of two additional signaling pathways in
mammalian cells that, together with Ire1, help maintain equilibrium in the face
of stress, averting a
host of diseases.
Expression profiling
of fungi and the
mammalian host during in vivo infections and ex vivo infections
of culture immune system cells
Currently, I study the prevalence, genetic diversity and evolutionary history
of Demodex lineages, in relation to both human populations, as well as other
mammalian hosts.
We thus aimed to grow any persistent B. burgdorferi present in the heart tissue
of our infected macaques within an isolated system exposed to a
mammalian host environment.
In this study, we investigated the role
of OspC in B. burgdorferi in both the tick vector and the
mammalian host.
The transient pattern
of ospC expression, coupled with the phenotype
of the mutant, suggests that OspC does not provide a physiologic function required for growth in the
mammalian host, but has a critical function early in
host infection, preceding the acquired immune response.
The Synthetic Biology Center at the Massachusetts Institute
of Technology is
hosting its Third International
Mammalian Synthetic Biology Workshop in May, which will feature keynote talks by Profs. Shelley Berger and Irving Weissman.
Genome analysis
of three Pneumocystis species reveals adaptation mechanisms to life exclusively in
mammalian hosts.
This rapid synthesis
of OspC by spirochetes during tick feeding may play an essential role in the capacity
of these bacteria to successfully infect
mammalian hosts, including humans, when transmitted by ticks.
As dogs have been infected with both
mammalian and avian influenza viruses, they have the potential to act like pigs, as «mixing vessel»
hosts for the generation
of new strains.