That being said, other types
of marker signals can absolutely be used in the same way as a clicker.
Not exact matches
Here we have again the phenomenon that City Council Watch has long identified as the
signal marker of a decayed political culture: the election
of Chiefs
of Staff to succeed their bosses.
After getting weekly injections for 5 weeks, the mice did not have elevated levels
of liver enzymes that
signal toxicity, and there was no increase in certain
markers of inflammation, or in antibodies that indicate an immune response.
Levels
of a nerve cell
signaling molecule called substance P — measured in tear samples — might be a useful
marker of diabetes - related nerve damage (neuropathy), suggests a study in the July issue
of Optometry and Vision Science, the official journal
of the American Academy
of Optometry.
Researchers found less evidence for the formation
of new blood vessels and fewer protein
markers that
signal neuroplasticity, or the brain's ability to make new connections between neurons.
The results showed that, when applied, a long - term inhibition
of Rho - kinase
signaling increased the expressions
of chondrocyte - specific genes and differentiation
markers in human chondrosarcoma 2/8 cells.
A specific genetic
marker influences response to therapy in the early stages
of RA; a link thought to be due to the gene activating a cell -
signalling protein involved in the inflammatory disease process.
When activated by inflammatory
markers in the gut, it sends a
signal to the brain, where immune cells produce proteins such as IL - 6, leading to increased metabolism (and hence decreased levels)
of the «happiness hormone» serotonin in the brain.
The ability to track
markers inside and outside a cell simultaneously, and to map them atop images showing the cell's shape, is also helping researchers study the metabolic effects
of signaling molecules, such as G - protein - coupled receptors.
Somatic
markers include the churning in our stomachs when we are anxious, a flushing
of the cheeks when we are embarrassed, wide - open eyes when we hear an idea that excites us, or a relaxation
of body muscles
signaling the relief we feel when we get something off our chest.
They found that ONC201 alters the gene expression
of cancer stem cell
markers and
signaling pathways prior to killing the tumor cells, providing pharmacodynamic biomarkers
of response.
The team developed a genetic
marker that
signals the presence
of those DNA segments in a concentrated water sample from the animals» environment.
The first page presents a diagram
of the sky overhead, with
markers pointing out the gps satellites above the horizon, as well as an indicator that shows the
signal strength coming from each satellite.
Scientists at The Institute
of Cancer Research (ICR) used the cells
of fruit flies, modified with a fluorescent
marker that is activated when the cells are put under stress, to identify the
signals responsible for driving up activity
of the ER.
To trace the lineage
of liver cells, scientists used a telltale
marker — the cells» response to
signals delivered by a known stem - cell regulator called Wnt.
Wang explained that, because ECMs are composed
of collagen, elastin, carbohydrates and
signaling molecules and have no cell surface
markers, DNA or RNA from the donor, the recipient is less likely to reject the treatment.
With SABT2 as a
marker, the researchers show BMP
signaling is required for development
of tissues specific to the posterior gut region
of frogs and mice where the colon develops.
The next step for her team is to start looking at individuals instead
of just populations, identifying blood
markers and other physiological
signals that illustrate how a person is responding to his or her environment, even before needing to go to the hospital.
Rats born
of hypoxic pregnancy with no vitamin C treatment showed increased thickening
of the walls
of the aorta — up to 170 % above normal — and molecular
markers of disease, such as an increase in the heart's heat shock proteins, a
signal of cardiac oxidative stress.
While expression levels
of all
marker genes remained almost unchanged in wild - type ACVR1 cultures compared with the empty viral vector, the expression profile induced by caACVR1 Q207D displayed evidence
of advanced chondrogenic differentiation as shown by decreased levels
of the early differentiation stage
marker collagen type II together with enhanced expression
of the later - stage
markers Ihh and collagen type X. Indian hedgehog has been shown previously to be induced by BMP
signaling transmitted via the ACVR1 receptor (9).
Using a novel methodology, the researchers found an association between the disorder and a DNA
marker that is very close to the dopamine transporter gene, which controls the intake
of this important neural messenger by the nerve cells that respond to dopamine's
signal.
Interestingly, transient BIO exposure (1 — 2 hours) prompted accelerated WNT
signaling in hMSCs and stimulated the expression
of early osteogenic
markers, such as the osteogenic master - regulator Runx2.
Thus, we concluded that Acks could be utilized as a
marker of neural activity that occurred 30 to 60 min before in the brains
of Japanese honeybees, although we could not detect the spotted
signal in the antennal lobes (ALs, primary olfactory center), suggesting that Acks, like kakusei, is not useful for detecting neural activity in the ALs (data not shown).
The group has found that a broad range
of potential physical, chemical and biological
markers characterise the Anthropocene, the clearest global
markers being radionuclide fallout
signals from nuclear testing and changes in carbon chemistry through fossil fuel burning — these in particular show marked changes starting in the early to mid-1950s.
The group, with a number
of invited scientists, has now reviewed present knowledge on where these and other
markers form the clearest, sharpest, and most stable
signal in strata that might be used to define the Anthropocene as a formal unit
of the Geological Time Scale.
To characterize activation
of immune cells, measurement
of intracellular
signaling using phospho - specific antibodies combined with immune phenotyping using surface
markers is ideal.
marker (in biomedicine) The presence
of some substance that usually can only be present because it
signals some disease, pollutant or event (such as the attachment
of some stain or molecular flag).
In one set
of experiments, when the scientists boosted insulin resistance by giving mice a compound that cuts insulin
signaling, they saw increased expression
of several
markers of aging in beta cells.
Fluorescence - based assays Fluorescent
markers such as EGFP, YFP, mCherry and mTomato or fluorescent biosensors can be used to measure a variety
of real - time cell - based activities, including, intracellular transport, protein
signaling, receptor desensitization, migration, division, apoptosis, metabolism, differentiation, chemotaxis, transcription and translation.
The results tell
of genetic
markers that, if present, may
signal susceptibilities to certain health conditions.
In conclusion, aging causes the loss
of many
of the anabolic
signals and an increase in catabolic
signals to muscle that are present in young adulthood, but this study suggests that whey protein, essential amino acid, and vitamin D supplementation, together with gentle physical activity, can produce changes in catabolic mediators, lowering inflammatory
markers such as CRP, and improving anabolic
markers such as IGF - I.
A number
of studies have implicated the immune system (responsive to oxidative stress
signals) in postpartum depression, as well as associated inflammatory
markers like CRP and IL6.
David Bordwell contends that Tarantino deliberately
signals his sources to his audience, «in order to tease pop connoisseurs into a new level
of engagement,» while Aaron C. Anderson writes that by using framing
markers and calculatingly phony distancing devices (like, for example, the black - and - white process shots in Pulp Fiction), «Tarantino draws attention to his film's status as a film, as a constructed work
of fiction, and as a «simulation.
If you need to change a burnt out rear turn
signal or rear side
marker light bulb in the tail light housings
of a 3rd generation (2015, 2016, 2017 & 2018) Nissan Murano SUV, check out my DIY directions for the procedure (with the compatible replacement part number) by clicking on the text link or thumbnail image below.
The styling difference from the 1967 to the 1968 model was the addition
of federally - mandated side
marker lights: for the front
of the car, the turn
signals were made larger and extended to wrap around the front edges
of the car, and on the rear, the Pontiac (V - shaped) Arrowhead logo was added to each side.
The headlight housings
of a 3rd generation (2015, 2016, 2017 & 2018) Nissan Murano contain the low beam, high beam, front turn
signal and side
marker light bulbs.
GE LIGHTING 212 LIGHT BULBS, WHITE, SET
OF 2 — 13.5 volts; 10 watts; Miniature type; Features miniature cap base with T and TL shape design; Can be used for under hood, back up, cornering, directional
signal indicator, dome, glove box, high mount stop, instrument, license plate, map, rear side
marker, courtesy, and cargo area lights; A high quality, OE replacement light bulb set; With GE Lighting limited warranty.
GE LIGHTING 194 LIGHT BULBS, WHITE, SET
OF 2 — 14 volts; 4 watts; Miniature type; Features wedge base with T and TL shape design; Can be used for under hood, ash tray, auto transmission indicator, back up, brake warning, check engine, clock, directional
signal indicator, dome, glove box, hi - beam indicator, high mount stop, ignition switch, instrument, license plate, map, parking, radio dial, seat belt warning, side
marker, courtesy, stop, tail, cargo area, and turn
signal lights; A high quality, OE replacement light bulb set; With GE Lighting limited warranty.
Includes 12 - way power driver and front passenger seat adjusters including 4 - way power lumbar control 2 - position driver memory adjustable head restraints (D07) floor console and storage pockets and (K4C) wireless charging (STD), LICENSE PLATE KIT FRONT, TRAILERING WIRING PROVISIONS FOR TRAILERING FIFTH WHEEL AND GOOSENECK TRAILER includes additional 7 - way wiring harness is located at the rear
of the pickup box attached to the rear frame cross member, DENALI PREFERRED EQUIPMENT GROUP includes standard equipment, TIRES LT265 / 60R20E ALL - TERRAIN BLACKWALL (STD), MIRRORS CHROME OUTSIDE HEATED POWER - ADJUSTABLE VERTICAL TRAILERING MEMORY - EQUIPPED UPPER GLASS POWER - FOLDING AND MANUAL EXTENDING; Includes integrated turn
signal indicators consisting
of 51 square inch flat mirror surface positioned over a 24.5 square inch convex mirror surface with a common head and lower convex spotter glass (convex glass is not heated and not power - adjustable) and addition
of auxiliary cargo lamp for backing up (helps to see trailer when backing up with a trailer) and amber auxiliary clearance lamp, LAMPS SMOKED AMBER ROOF
MARKER, HILL DESCENT CONTROL, LPO REAR UNDERSEAT STORAGE COMPOSITE STORAGE BIN, DURAMAX PLUS PACKAGE includes (L5P) Duramax 6.6 L Turbo - Diesel V8 engine and (VQY) chrome recovery hooks LPO (MW7) Allison 1000 6 - speed automatic transmission (Includes (DQS) outside memory equipped heated power - adjustable vertical trailering mirrors.)
The same camera array is used to detect the lane
markers and power the lane - departure warning system that alerts the driver when the vehicle drifts out
of its lane without a turn
signal at speeds above 35 mph.
Typically, bulbs
of 21 to 27 watts producing 280 to 570 lumens (22 to 45 mean spherical candlepower) are used for stop, turn, reversing and rear fog lamps, while bulbs
of 4 to 10 W, producing 40 to 130 lm (3 to 10 mscp) are used for tail lamps, parking lamps, side
marker lamps and side turn
signal repeaters.
So each time you are doing practice departures, you can use an associated cue or
marker to
signal this fact and then, once you have worked up practice departures to a time frame
of around one to two hours (during which most dogs with separation anxiety typically have issues), you can use the cue during actual departures to function to «bridge» from practice to actual departures.
To help the animals associate the
marker signal with the desired behavior (in other words, to help a dog understand that a «click» sound they heard is matched to something they just did — such as sit down), many positive reinforcement trainers start with a game
of «target» to teach the relationship between the
marker signal («you got it!»)
But the Wisdom Panel 2.0 is able to identify strong breed
signals (
markers that are consistent with the presence
of a particular breed) in this mixed portion.
But the advantage
of using a clicker (or some other
marker signal) is that it's a crisp, clear, unique sound that can't be mistaken for anything else.
You use a
marker signal (the sound
of a toy clicker) to tell the animal (or person) when it's doing the action that will pay off.
We all agree on the benefits
of using clicker training principles (regardless
of if you use a clicker, verbal
marker, whistle, etc.) for marking wanted behaviors, however where the discussions come in is when
signals are used to mark the moment that the dog failed to perform or missed, some dog trainers tend to use
signals to inform their dogs that they have failed, still others say that these such
signals are not necessary or even that they produce unnecessary stress, etc..
The field
of dog training is fascinating and endlessly rewarding, due to the emergence
of positive reinforcement training using a
signal marker.
The imagery
of the journey is dotted by
markers of industry, refracted light, ships as shadows in the distance, and boiler rooms
of infinite gauges; with Morse code and jamming radio
signals providing a continuous backing track.
Because there is a real difference between environmental concern — where consequences matter — and environmentalism — where
signalling adherence to the appropriate
markers of concern (based on human action being presumptively destructive) matter.