(CAMBRIDGE, Mass.)-- Researchers in the field
of mechanobiology are revealing new insights into how the body's physical forces and mechanics impact development, physiological health, and the prevention and treatment of disease.
Not exact matches
Data from these studies will provide the controlled mechanical environment for studies
of breast cancer
mechanobiology.
This collaboration reflects work
of The Center for Engineering
Mechanobiology, a National Science Foundation - funded Science and Technology Center that supports interdisciplinary research on the way cells exert and are influenced by the physical forces in their environment.
One area
of research within
mechanobiology, the study
of how physical forces influence biological processes, is on the interplay between cells and their environment and how it impacts their ability to grow and spread.
The study, published in the Proceedings
of the National Academy
of Sciences, was led by Vivek Shenoy, professor in the Department
of Materials Science and Engineering and co-director
of Penn's Center for Engineering
Mechanobiology, along with Xuan Cao and Ehsan Ban, members
of his lab.
Lim's team sits in the NUS
Mechanobiology Institute and the faculty
of engineering, and as he consults with biologists and clinicians as dictated by the nature
of his various projects, he stresses the need for engineers and physical scientists to partner with medical doctors early and regularly in the innovation process.
A team
of researchers, led by Keiko Kawauchi from the
Mechanobiology Institute at the National University
of Singapore, studied cells that had been transformed into cancer cells by Ras, the most common oncogene in human cancer.
«New
mechanobiology technique to stop cancer cell migration: Researchers have synthesized a molecule that targets the membranes
of cervical cancer cells to block their migration.»
Researchers from the
Mechanobiology Institute, Singapore (MBI) at the National University
of Singapore, report that endocytosis, which was previously thought to be a random process, actually occurs in a coordinated manner through collective dynamics.
Researchers at the
Mechanobiology Institute (MBI), National University
of Singapore (NUS) have identified a novel mechanosensitive regulation
of epithelial tube contraction.
«The role
of mechanical forces in the behaviour
of biological cells has long been overlooked, but then has become a rapidly growing field
of research over the last two decades now known as
mechanobiology,» states Prof. Schwarz.
A multi-disciplinary team
of researchers from the
Mechanobiology Institute, Singapore (MBI) at the National University
of Singapore (NUS), the Institute
of Bioengineering and Nanotechnology (IBN)
of A * STAR, and BioSyM, Singapore - MIT Alliance for Research and Technology have described the mechanical principles adopted by liver cells as they remove excess bile during obstructive cholestasis.
Another aspect has something to do with a more recent field
of cell biology, the
mechanobiology.
Researchers at the
Mechanobiology Institute have comprehensively described the network
of proteins involved in cell - cell adhesions, or the cadherin interactome.
To better identify the components
of this wider network in maintaining and regulating adhesion, researchers at the
Mechanobiology Institute, National University
of Singapore, applied a combination
of experimental and computational techniques to reveal and dissect the complex network
of proteins that interact with E-cadherin.
Judah Folkman Award in Vascular Biology Lecture Insights into the
Mechanobiology of the Endothelium Guillermo García - Cardeña, Brigham and Women's Hospital, Harvard Medical School