Discordant Lymphoma Consisting
of Mediastinal Large B - Cell Lymphoma and Nodular Sclerosis Hodgkin Lymphoma in the Right Supraclavicular Lymph Nodes: A Case Report.
Not exact matches
Radiation to the primary disease site was delivered via SAbR where possible, or through 15 fractions
of hypofractionated radiation therapy if the primary tumor was too central or involved
mediastinal nodes.
The objective was further explore and analyze the impact on prognosis
of tumor size and
of the different T descriptors; the prognostic significance
of tumor burden in hilar and
mediastinal lymph nodes; and the confirmation
of the revised M1 categories (M1a and M1b)
of the seventh edition
of the classification along with the prognostic impact
of number and anatomic location
of metastases.
Amplification
of the JAK2 locus has been described in Hodgkin disease and
mediastinal B - cell lymphoma, 18,19 and biallelic inactivating mutations in suppressor
of cytokine signaling - 1 (SOCS - 1), a negative regulator
of JAK2, have been identified in
mediastinal B - cell lymphoma.20 Genomic analysis
of JAK2 and
of other JAK - STAT pathway members may lead to the identification
of mutations
of the JAK - STAT pathway in lymphoid diseases and other malignancies.
These patients had either chemorefractory DLBCL or variants
of DLBCL like primary
mediastinal B - cell lymphoma or transformed follicular lymphoma.
In the days prior to the release
of the vaccine for the feline leukemia virus,
mediastinal lymphoma was the most common form
of feline lymphoma.
Possible causes
of chylothorax include anterior
mediastinal masses (
mediastinal lymphosarcoma, thymoma), heart disease (cardiomyopathy, heartworm disease, congenital cardiac diseases, etc.), fungal granulomas, congenital abnormalities
of the thoracic duct, and diffuse lymphatic abnormalities.
This type
of lymphoma is known as
mediastinal lymphoma.
Mediastinal lymphoma in cats with feline leukemia carries a poor prognosis, with an average survival time
of 3 months.
Mediastinal: The mediastinum is a term used for a special aggregation
of lymphoid tissue in the chest.
Findings include increased
mediastinal soft tissue opacity with or without tracheal narrowing, variable amounts
of pleural effusion, and patchy pulmonary infiltrates.
In the days before the vaccine for the feline leukemia virus,
mediastinal lymphoma was the most common form
of feline lymphoma.
Precaval syndrome (swelling
of the head, neck, and / or thoracic limbs) is possible if the
mediastinal mass causes compression
of or invades the cranial vena cava.
Clinical signs are variable and are related to a space - occupying cranial
mediastinal mass and / or manifestations
of the paraneoplastic syndrome.
Members
of some cat breeds are predisposed to
mediastinal lymphosarcoma, such as the Oriental and Siamese breeds.