Sentences with phrase «of medicinal chemistry»

This process of medicinal chemistry is a long and slow one, but having skilled people who can help with this is absolutely essential in the drug discovery and development process.

«The cortex basically takes all the information coming in and synthesizes it into reality,» says David E. Nichols, a professor of medicinal chemistry at Purdue University in West Lafayette, Indiana, who has done animal research on hallucinogens.

Suppliers sometimes pass off cheaper defrosted meat as fresh, according to Laurie Hall, professor of medicinal chemistry at the University of Cambridge.

Yu, L. F., Tuckmantel, W., Eaton, J. B., Caldarone, B., Fedolak, A., Hanania, T., Brunner, D., Lukas, R. J., and Kozikowski, A. P. Identification of Novel alpha4 beta2 - Nicotinic Acetylcholine Receptor (nAChR) Agonists Based on an Isoxazole Ether Scaffold that Demonstrate Antidepressant - like Activity, Journal of medicinal chemistry.

«Companies have amassed large — and in some cases very high quality — compound libraries,» says Lee Flippin, senior director of medicinal chemistry at FibroGen.

As a graduate student, she was a member of the Interdisciplinary Program of Drug Discovery, where she gained vital exposure to the multidisciplinary fields of medicinal chemistry, pharmacology, and chemical biology.

David Rees, senior vice president of medicinal chemistry at Astex Therapeutics, a fragment - based drug discovery specialist based in Cambridge, keeps a keen eye on the recruitment market in the city.

Researchers led by Judy Bolton, professor and head of medicinal chemistry and pharmacognosy in the UIC College of Pharmacy, applied hops extract to two different breast cell lines to see if they would affect estrogen metabolism, a key mechanism in breast cancer.

Harold Kohn, Kenan chair of the division of medicinal chemistry and natural products, who has frequently collaborated with Tropsha, says, «The speed of computer - aided drug discovery fits Alex's personality.

In the video «The power of medicinal chemistry», Giralt highlights his interest in deciphering the language used by proteins to interact with each other.

His work focuses on the application of medicinal chemistry to the development of novel agents for the treatment of tuberculosis.

«With food sources versus supplements, there's more potential to buy a product that doesn't contain probiotics — or if it does, those probiotics may not be viable,» says Lynne V. McFarland, Ph.D., affiliate associate professor in the department of medicinal chemistry at the University of Washington and co-author of The Power of Probiotics: Improving Your Health with Beneficial Microbes.

«The bactericidal mechanism of ODLs and the fact that they bind to a site on the ribosome not exploited by any known antibiotic are very strong indicators that ODLs have the potential to treat infections that are unresponsive to other antibiotics,» said Mankin, who is also professor of medicinal chemistry and pharmacognosy.

Liu, J., Yu, L. F., Eaton, J. B., Caldarone, B., Cavino, K., Ruiz, C., Terry, M., Fedolak, A., Wang, D., Ghavami, A., Lowe, D. A., Brunner, D., Lukas, R. J., Kozikowski, A. P. Discovery of Isoxazole Analogs of Sazetidine - A as Selective alpha4 beta2 - Nicotinic Acetylcholine Receptor (nAChR) Partial Agonists for the Treatment of Depression, Journal of medicinal chemistry 2011 54, 7280 - 7288

Sumit Chanda, Ph.D., professor and director of the Immunity and Pathogenesis Program at Sanford Burnham Prebys Medical Discovery Institute (SBP), and Anthony Pinkerton, Ph.D., director of medicinal chemistry at SBP's Conrad Prebys Center for Chemical Genomics, are collaborators on the effort.

Another tweak replaced an amide bond in the BMS compound with slightly different bonds that are known in the field of medicinal chemistry to mimic an amide bond.

«We're not only about discovery science but also translation science from which we can derive benefits for mankind,» explains Mark von Itzstein, executive director of the Institute for Glycomics and professor of medicinal chemistry and federation fellow at GriffithUniversity.

Douglas Thomas, associate professor of medicinal chemistry and pharmacognosy at UIC, and co-workers discovered that nitric oxide plays an important role in epigenetics — heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence.

She and Guido Pauli, professor of medicinal chemistry and pharmacognosy in the UIC College of Pharmacy, recently collaborated on another study that showed extract from the root bark of Chinese red pine trees has similar properties to the grape seed extract.

Richard van Rijn, an assistant professor of medicinal chemistry and molecular pharmacology, looked at the effects of highly caffeinated energy drinks and highly caffeinated alcohol in adolescent mice.

Yu L.F, Tuckmantel W, Eaton J.B, Caldarone B, Fedolak A, Hanania T, Brunner D, Lukas R.J, Kozikowski A.P. Identification of Novel alpha4 beta2 - Nicotinic Acetylcholine Receptor (nAChR) Agonists Based on an Isoxazole Ether Scaffold that Demonstrate Antidepressant - like Activity, Journal of medicinal chemistry.

Renowned Chemist Joins Scripps Florida - William R. Roush has been named professor of chemistry, executive director of medicinal chemistry, and associate dean of Florida graduate programs.

He became a professor of medicinal chemistry and chemistry at Northeastern University in 1969, was appointed Matthews Distinguished Professor in1980, and was a...

John S. Williamson, PhD Professor of medicinal chemistry and research professor, Research Institute of Pharmaceutical Sciences, The University of Mississippi.