Sentences with phrase «of mesenchymal stem cells»

The present and potential clinical applications of mesenchymal stem cell therapy in cats are explored in a state - of - the - art review article published this month in the Journal of Feline Medicine and Surgery.
Scientists have now discovered that the umbilical cord contains a jelly - like material within its wall called Wharton's jelly, which is one of the richest sources of mesenchymal stem cells capable of self - renewal and differentiation.
Review of «Intra-articular injection of mesenchymal stem cells for the treatment of osteoarthritis of the knee: A proof - of - concept clinical trial» from Stem Cells by Stuart P. Atkinson
Pretransplant infusion of mesenchymal stem cells prolongs the survival of a semiallogeneic heart transplant through the generation of regulatory T cells.
In a review published in the Journal of Feline Medicine and Surgery, Jessica M. Quimby, DVM, Ph.D., DACVIM, Department of Veterinary Clinical Sciences at The Ohio State University, and Dori L. Borjesson, DVM, MPVM, Ph.D., Veterinary Institute for Regenerative Cures at the University of California, Davis, consider both the current and potential clinical applications of mesenchymal stem cell therapy in cats.
Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis.
Intra-articular injection of mesenchymal stem cells for the treatment of osteoarthritis of the knee: A proof - of - concept clinical trial.
A research group led by Osaka University found a plant - based polyphenol, promotes the migration of Mesenchymal Stem Cells (MSCs) in blood circulation and accumulates them in damaged tissues to improve wound healing.
A Novel Role for CAMKK1 in the Regulation of the Mesenchymal Stem Cell Secretome.
Review of «A Novel Role for CAMKK1 in the Regulation of the Mesenchymal Stem Cell Secretome» from STEM CELLS Translational Medicine by Stuart P. Atkinson
They used cytochalasin D, a naturally occurring substance found in mold, as a proxy to alter gene expression in the nuclei of mesenchymal stem cells to force them to become osteoblasts (bone cells).
The review's authors, Dr Jessica Quimby, of the Department of Veterinary Clinical Sciences at Ohio State University, and Dr Dori Borjesson, of the Veterinary Institute for Regenerative Cures at the University of California - Davis, consider the emergence of this new therapeutic strategy and the current understanding of the biology and immunology of mesenchymal stem cells.
His current research uses a variety of molecular, biochemical, and genetic approaches to study the basic biology of mesenchymal stem cells (MSCs).
In this webinar, Dr. Stoddart will show identifying cell fate of mesenchymal stem cells is more accurate and specific when studying the expression ratios of multiple targets as opposed to studying them in isolation.
This phase I study suggests that intratracheal administration of mesenchymal stem cells is safe and feasible.
PhD Title: «Small - Molecule Antagonist of an Inflammatory Cytokine Enhances Migration of Mesenchymal Stem Cells»
The robust immunomodulatory capabilities of mesenchymal stem cells (MSCs) have propelled them into animal studies and preliminary clinical trials as a treatment for a series of immunological diseases.
The overexpression of basic fibroblast growth factor boosts bone fracture healing capacity of mesenchymal stem cells via the secretion of paracrine - acting factors
In our latest work, for example, we have found evidence of a potentially clinically useful connection of complement in mesenchymal stem cell - based therapies, suggesting that complement is a valid target for improving the viability and function of mesenchymal stem cells, which are under extensive evaluation in clinical trials for treating many inflammatory and degenerative diseases.
Comparison of mesenchymal stem cells from human placenta and bone marrow.
Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals.
Phinney DG Biochemical heterogeneity of mesenchymal stem cell populations: clues to their therapeutic efficacy.
Devine SM, Hoffman R. Role of mesenchymal stem cells in hematopoietic stem cell transplantation.
Pre-clinical evidence concerning the utility of mesenchymal stem cells (MSCs) to aid the treatment of acute lung injury (ALI) has been mounting over recent years, with some clinical trials beginning to run.
In addition to these applications, new uses may be developing; these involve the transfer of genes with the potential of increasing efficacy â $» for example, the transduction of mesenchymal stem cells with transforming growth factor Î ² 1 to allow chondrogenesis to occur in vitro before the cells are used clinically.
Although researchers reported the existence of mesenchymal stem cells (MSCs) as early as the 1960s and 1970s, they were excluded from the stem cell family for decades.
Researchers using a novel technique find that potential therapeutic worth of mesenchymal stem cells is linked to their motility
A trial to assess the anti-inflammatory properties of mesenchymal stem cells (MSCs) to improve heart function in patients with heart disease.
New research suggests that potentiating the AKT - mTOR signaling axis can boost tenogenesis of mesenchymal stem cells and improve current tendon repair strategies
New research demonstrates that immune cells help to mediate, distribute, and transfer the immunomodulatory effects of mesenchymal stem cells following systemic administration
The generation of mesenchymal stem cells (MSCs) from patient - specific induced pluripotent stem cells (iPSCs) may represent a convenient source of autologous cells for therapeutic purposes.
The most common supply of mesenchymal stem cells has to date been from bone marrow.
Early intervention of mesenchymal stem cell therapy for cats with chronic gingivostomatitis; (MT17 - 008) Principal Investigator: Boaz Arzi, DVM, PhD, DADC, Dori Borjesson, DVM, PhD, DACVP, Frank Verstraete, Professor; University of California - Davis.
The initial emphasis of the program was to target the potential of mesenchymal stem cells (MSCs) for orthopedic repair in horses, including bone healing and tendon and ligament repair.
Your fat tissue contains the most abundant source of mesenchymal stem cells (MSCs) in your body — a class of repair cells which have the ability to decrease inflammation, repair or replace damaged tissue while stimulating new blood vessel growth for improved blood flow.
They also summarise the outcome of clinical trials that have investigated the use of mesenchymal stem cells in the treatment of a number of inflammatory, degenerative and immune - mediated diseases of cats.
A group of researchers led by Kosuke Fujita, Visiting Researcher and Akito Maeda, Specially Appointed Professor at the HP Skin Regeneration, PIAS Collaborative Research, Osaka University clarified that cinnamtannin B - 1, or vegetable - based polyphenol, promotes the migration of Mesenchymal Stem Cells (MSCs) in blood circulation and accumulates them in damaged tissues (Fig. 1) to improve wound healing.
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