Sentences with phrase «of metabolic abnormalities»

In a study of humans, scientists connected an increased risk of metabolic abnormalities like diabetes and metabolic syndrome with low serum amylase levels.

Studies in dogs indicate that the parenteral administration of a single dose of cyanocobalamin (250 - 500 µg SQ once per month) is enough to prevent recurrence of metabolic abnormalities for up to one month.

The offspring mice did NOT, however, develop any of the metabolic abnormalities, weight gain, or insulin resistance that are characteristic of PCOS.

Finally, and possibly most importantly this study doesn't explain ANY of the metabolic effects so strongly linked to PCOS, as giving a massive injection of AMH to the pregnant mice still did NOT induce any of the metabolic abnormalities or insulin resistance that are so characteristic of the vast majority of women with the condition.

We also know that high testosterone in pregnancy cause gut microbiota changes in the offspring that are characteristic of the metabolic abnormalities found in PCOS.

Identification and correction of these metabolic abnormalities, including leptin resistance and cellular thyroid dysfunction, can result in dramatic long term successful weight loss.

Metabolic syndrome is a group of metabolic abnormalities, including abdominal obesity, elevated serum triglycerides, low HDL - cholesterol, elevated blood pressure and insulin resistance.

We speculate this to be the case, as resetting of metabolic abnormalities is needed for recovery of IBD patients who have metabolic syndrome disorder (Goncalves et al., 2015).

Mice lacking insulin receptor in brain or on hypothalamic neurons display an array of metabolic abnormalities, however, the role of insulin action on astrocytes and neurobehaviors remains less well - studied.

The expert team in the Division of Pediatric Nephrology at Floating Hospital for Children provides comprehensive evaluation and treatment for the range of metabolic abnormalities.

Within diabetic populations, hyperglycaemia is considered the hallmark diagnostic marker of metabolic abnormality and a major contributor to T2DM associated macro - and micro - vascular complications.61 One study by Ash et al 36 saw 51 overweight / obese male subjects with T2DM assigned to one of three groups; (i) IER (four days 50 % ER, three days ad libitum intake / week), (ii) CER (30 % ER / day, all meals provided) and (iii) CER (30 % ER / day, food self - selected by the participant).

Not exact matches

A research finding in January 2017 reveal that Golden Rice hybrid with Swarna variety resulted to phenotyphic abnormalities, stunted growth and low yield, virtually adulterating the metabolic and genetic traits of the variety.

[Preemies receiving higher amounts of protein grew faster but: «This benefit could not be weighed against the adverse consequences of elevated blood urea nitrogen levels and increased metabolic acidosis and neurodevelopmental abnormalities.»]

However, investigating metabolic abnormalities in the brain has been hindered by lack of a good imaging tools.

This suggests these women had more serious underlying metabolic abnormalities that made them more susceptible to gestational diabetes, even without the added impact of a developing male fetus, Shah said.

Besides getting fatter, we are also developing more metabolic disorders, such as type 2 diabetes, which is marked by hormonal abnormalities in the processing and storage of nutrients and is far more common in obese individuals than in lean ones.

«We now have a really good picture of this abnormality in mice, and we suspect it is very similar in humans,» said Fuming Zhang, a research professor in the laboratory of Robert J. Linhardt, the Ann and John H. Broadbent Jr»59 Senior Constellation Professor of Biocatalysis and Metabolic Engineering, and a member of the Center for Biotechnology and Interdisciplinary Studies at Rensselaer.

«In young and middle - aged adults, our findings suggest that early detection and treatment of mild - to - moderate sleep apnea is warranted in order to prevent future cardiometabolic disease,» said lead author and postdoctoral scholar Yun Li, MD. «Given the stronger association of sleep apnea with metabolic abnormalities in this age group, emphasis should be placed on yearly monitoring of indices of metabolic symptoms and lifestyle interventions, such as weight control, healthy diet, regular exercise, and stress management.»

A person meets the criteria of the metabolic syndrome if they have three or more of the following metabolic abnormalities: blood pressure at 130/85 mm Hg or above; fasting glucose of 100 mg / dL or higher; waist circumference 40 inches or more in men and 35 inches in women; triglyceride levels at 150 mg / dL or more, and high - density lipoprotein cholesterol (HDL - C) greater than 40 mg / dL in men and 50 in women.

Metabolic syndrome, a cluster of cardiometabolic conditions, may be a biological mechanism linking posttraumatic stress disorder (PTSD) to structural brain abnormalities, according to a new study in Biological Psychiatry.

High blood pressure during pregnancy is a risk factor for future hypertension and cardiovascular disease, but it's not clear if this increased risk is because these women are more likely to have a family history of heart disease or if elevated blood pressure during pregnancy causes long - term metabolic and vascular abnormalities.

The new study by NYU Langone Medical Center researchers reveals that mice given lifelong low doses of penicillin starting in the last week of pregnancy or during nursing were more susceptible to obesity and metabolic abnormalities than mice exposed to the antibiotic later in life.

Researchers said their evidence further strengthens the concept that transportation noise contributes to the development of heart disease risk factors such as hypertension and diabetes because noise is associated with oxidative stress, vascular dysfunction, autonomic imbalance and metabolic abnormalities.

Nevertheless, the balance of sex hormones appears important as inappropriate low testosterone, or high estrogen concentrations in males, may also relate to fatty liver disease and metabolic abnormalities.

It is unfortunate that the investigators did not assess insulin secretion, insulin action, or systemic inflammation in early - aging BubR1H / H; INK - ATTAC mice, with and without ablation of senescent adipose cells, but reasonable to be optimistic that doing so would yield some normalization of age - related metabolic abnormalities.

These findings are consistent with metabolic or microstructural abnormalities in bipolar disorder and draw attention to roles of the cerebral white matter and cerebellum.

These age - related abnormalities then drive a range of unhealthy metabolic changes, including a reduced ability to move blood sugar out of the blood in response to the hormone insulin.

While extreme, these surgeries have proven the point that the metabolic abnormalities that underlie T2D (hyper insulinemia, insulin resistance) can often be fully reversed after a short (weeks) period of intensive treatment with bariatrics.

Roland Rosmond, Mary F. Dallman and Per Björntorp, Stress - Related Cortisol Secretion in Men: Relationships with Abdominal Obesity and Endocrine, Metabolic and Hemodynamic Abnormalities, The Journal of Clinical Endocrinology & Metabolism, 1998, Vol.

If three or more abnormalities are present, we refer to the condition as metabolic syndrome (MS), which predicts an increased risk of heart disease and developing full - blown type 2 diabetes.

Circulating concentrations of endothelial adhesion molecules and inflammatory cytokines are highly correlated with insulin resistance and its related metabolic abnormalities.

Overview: Favism disease is a genetic metabolic abnormality caused by deficiency of the enzyme glucose -6-phosphate dehydrogenase...

Develop as a result of lifestyle - sex, age, alcohol consumption, smoking and common metabolic abnormalities (hyperlactemia which is an Increased level of lactate — A salt or ester of lactic acid in the blood — without evidence of lactic acidosis or shock, hemochromatosis which is an iron metabolism disorder, Acid Lipase Disease — an inability to breakdown fats and as a result fats build up in the cells of the body — is a lipid metabolism disorder

«Use of P - 31 magnetic resonance spectroscopy to detect metabolic abnormalities in muscles of patients with fibromyalgia.»

«A prominent and well - characterized feature of AD is progressive, region - specific declines in the cerebral metabolic rate of glucose (CMRglc)-LSB-...] Carriers of a common Alzheimer's susceptibility gene [APOE Ɛ4] have functional brain abnormalities in young adulthood, several decades before possible onset of dementia.

GW510516, a PPARd agonist retracts a number of abnormalities connected with the metabolic syndrome without escalating oxidative stress.

If this condition isn't corrected, it can lead to a whole host of serious illnesses including cardiovascular disease, blood pressure abnormalities, sleep apnea, low testosterone, metabolic syndrome, and cancer.

Reversal of behavioral and metabolic abnormalities, and insulin resistance syndrome, by dietary restriction in mice deficient in brain - derived neurotrophic factor

A person with insulin resistance will divert a greater proportion of dietary carbohydrate to the liver where much of it is converted to fat (that is, de novo lipogenesis), as opposed to being oxidized for energy in skeletal muscle.30 Although Hellerstein31 has recently reported that de novo lipogenesis contributes only ∼ 20 % of new triglycerides, this greater conversion of dietary carbohydrate into fat, much of it entering the circulation as saturated fat, is a metabolic abnormality that significantly increases risk for diabetes and heart disease.

In some people, they're related to metabolic abnormalities in other parts of the body, some of which stem from chronically high insulin.

The researchers concluded that almonds improved these markers of metabolic syndrome, a group of abnormalities that harm health and lead to diabetes.

In the initial report, mice harboring a mutation in the core circadian gene Clock (termed Clock mutant mice) were fed a high - fat (HF) diet and observed to develop obesity at a young age, as well as a variety of metabolic and endocrine abnormalities consistent with the metabolic syndrome (2).

First noticed in dogs some 75 years ago, vitamin deficiencies can lead to widely ranging clinical abnormalities that reflect the diversity of their metabolic roles.

These include, but are not limited to, diseases of the respiratory tract such as pneumonia, recurrent airway obstruction (RAO or heaves), and exercise induced pulmonary hemorrhage (EIPH); neurological abnormalities such as wobbler's syndrome and equine protozoal myeloencephalitis (EPM); gastrointestinal diseases such as colic, diarrhea, equine gastric ulcer syndrome (EGUS), and weight loss; endocrine conditions such as equine metabolic syndrome (EMS) and Pituitary Pars Intermedia Dysfunction (PPID, or Equine Cushing's syndrome); neonatal foal care; and many more.

Metabolic bone disease: any of a number of diseases affecting the bones due to an abnormality of metabolism.

- Serum chemistry — Gives us information about the condition of your pet's kidneys, liver, pancreas and helps identify any metabolic abnormalities

With few exceptions, regardless of the many different presentations of chronic heart disease in dogs and cats, whether primarily or secondarily, there are metabolic and structural abnormalities at the level of the heart muscle.

The immediate goals of treating canine parvoviral infection are to reverse the dehydration, electrolyte and metabolic abnormalities caused by the disease and to prevent or eliminate secondary bacterial infections.

The diagnostic tests also reveal the evidence of bacterial sepsis, metabolic abnormalities, cell damages, secondary organ injury and the presence of accompanying diseases, if any.

The similar responses in echinoplutei across regions, including smaller arms, changes in morphometry and increased abnormality and mortality are likely owing to the interactive effects of this metabolic stressor (hypercapnia) and the toxic effects of acidification on regulation of development and body patterning.