It is satisfying to be able to use my understanding
of microbial systems and apply them to other systems — instead of a lake, it can be the rumen of a moose or the intestine of a rat, said Stefan Bertilsson.
The study is the result of one the first collaborations from the Microbiome Center, a joint effort by the University of Chicago, the Marine Biological Laboratory and Argonne National Laboratory to support scientists at all three institutions who are developing new applications and tools to understand and harness the capabilities
of microbial systems across different fields.
«This is a tremendous innovation for in situ studies as a new means to interrogate the chemical language
of microbial system interactions, as well as being relative to the discovery and development of new electrode materials for energy storage,» said Dr. Louis Terminello, who leads chemical imaging work at PNNL.
Not exact matches
The PhytoShield ™ Flavor Enhancer line can be customized to a food
system to address a broad range
of product quality goals related to flavor,
microbial degradation, and shelf life with a single, natural technology.
The treatment plant reduces the high levels
of Suspended Solids (SS) and Biological Oxygen Demand (BOD) in the wastewater sufficiently to allow discharge into the local authority's sewerage
system without the requirement for costly
microbial after - treatment.
Understanding the role
of each group
of microbes in the breast milk would also provide leads to the pharmaceutical industry in harnessing
microbial power to boost our immune
system from various illnesses and allergies.
These samples will help educate researchers on the impact
of water re-use
systems on
microbial diversity.
While the Rockland County Commissioner
of Health Dr. Patricia Ruppert stated that measurements did not reach levels that represent a public health concern, turbidity can interfere with disinfection and provide a medium for
microbial growth; may indicate the presence
of disease causing organisms; and those dynamics can have effects on health, particularly those with compromised immune
systems.
The eight - member team concluded «that inter-host dispersal can alter the diversity and composition
of microbial communities and overwhelm the effects
of the host's innate immune
system.»
An example
of fermentation engineering is the development
of a
microbial culture - based treatment
system to degrade a phenol, which is toxic and very stable, to a liquid that can be safely disposed.
The researchers were exploring how to manipulate bacterial flow, as a way to prevent biofilms — dense layers
of microbial slime that can take over shower stalls, clog filtration
systems, and cling to ship hulls.
The team, led by doctoral student Adam R. Burns, now a postdoctoral researcher at Stanford University, compared what they found in the fish with predictions from computer modeling
of microbial dynamics performed by co-author Elizabeth Miller
of the META Center for
Systems Biology.
The oozy red slush
of Blood Falls in Antarctica's McMurdo Dry Valleys contains teeming
microbial life — and may be a sample
of a deep briny groundwater
system hundreds
of meters below the surface.
«Nerves control the body's bacterial community: Research team proves, for the first time, that there is close cooperation between the nervous
system and the
microbial population
of the body.»
«We added lower concentrations [
of silver] to a more complex
system, but rather than find no measurable effect, we found that the silver nanoparticles significantly altered the plant growth,
microbial biomass and
microbial activity.»
What's more, the studies suggest how our gut microbes make the immune
system turn against nerve cells — a finding that could lead to treatments, like drugs based on
microbial byproducts, that might improve the course
of the disease.
Professor Imogen Foubert from the KU Leuven Department
of Microbial and Molecular
Systems explains: «Cocoa butter crystallises as the liquid chocolate hardens.
The new study, by researchers at the University
of Vienna and the International Institute
of Applied
System Analysis explores the role
of microbial cheaters for soil carbon and nitrogen cycling using a computer model.
The research also shows that the presence
of microbial cheaters may help the soil
system to react more flexibly to changes in environmental conditions.
An exhaust vent leading from one
of the facility's «clean rooms» to the roof lacked a filter or screen, for example, and flaws in the air handling
system could expose sterile drugs to
microbial contamination during processing.
«In all
of our studies, we're working with people who know the microbes well, and we help them decide how viruses might be helpful to the
microbial system.
Systemic discovery
of antiphage defense
systems in the
microbial pangenome.
When we think
of how we fight disease, the image
of cells in our immune
system fending off
microbial invaders often comes to mind.
Scientists already know that the possession
of certain immune
system genes makes people more likely to develop MS, and it could be that these genes make people prone to autoimmune reactions when faced with
microbial molecular mimicry.
The challenge is to engineer a
system where we get enough growth to have a productive
microbial «chemical factory» but not so much that we can't channel enough
of the sugars into a pathway to make large quantities
of our target molecules,» says Kristala Prather, an associate professor
of chemical engineering at MIT and the senior author
of the study.
Through considerations
of developmental
systems perspectives, epigenetics, and
microbial life, Dupré challenges widely held assumptions about biology and evolution.
The discovery demonstrates the value
of using
microbial systems to investigate ecological and evolutionary questions, and has strong implications for our understanding and even treatment
of infectious diseases.
The study suggests a new method to show how
microbial communities, including those responsible for illnesses like Legionnaires» disease, may assemble inside the plumbing
systems of homes and public buildings.
Principle topics
of the ocean margin
systems workshop were
microbial systems in sedimentary environments, fluid flow and subsurface material transport, margin building / regulating processes, and benthic population dynamics and relationships to sedimentary settings.
Andrew Steele uses traditional and biotechnological approaches for the detection
of microbial life in astrobiology and solar
system exploration.
«We have become increasingly aware
of how crucially important a healthy gut
microbial population is for a well - functioning immune
system.
This is also the goal
of many other current research projects
of the Department
of Computational
Systems Biology, which focuses on research on pathogens,
microbial communities and molecular interactions between species adopting a
system - oriented approach.
The immune
system maintains a rich abundance
of «natural killer» cells to confront
microbial invaders, but as the body gains the upper hand in various infections it sometimes starts to produce even more
of the cells.
«The fact that we could alleviate inflammation by adding back a single key bacterial strain, suggests that it could be useful as a probiotic for inflammatory diseases,» said Rolig, who, along with Eisen, is a scientist in the National Institutes
of Health - funded
Microbial Ecology and Theory
of Animals Center for
Systems Biology, known as the META Center, which Guillemin heads.
«Plants and their
microbial neighbors have this beautifully complex and intricate
system of communicating through chemical signals, with each trying to manipulate the situation to maximize their own fitness,» Bais says.
Tilled
systems that used a chisel plow were equivalent to no - till
systems, in terms
of microbial biomass.
«What we're trying to understand in the extreme
systems is, what are the environmental drivers that are motivating the composition and structure
of the [
microbial] community?»
The biggest mystery in the microbiome field is whether
microbial changes are a cause or an effect
of problems with the immune
system, Dongari - Bagtzoglou says.
Finding out how methane and other organic species are formed in deep - sea hydrothermal
systems is compelling because these compounds support modern day life, providing energy for
microbial communities in the deep biosphere, and because
of the potential role
of abiotically - formed organic compounds in the origin
of life.
Clement Furlong, a researcher in medical and genomic sciences at the University
of Washington notes that the «huge advantage»
of these heavy - chain - only antibodies «is that you can make them by fermentation in
microbial systems and make a lot
of antibodies inexpensively.»
The
system is an evolutionarily ancient branch
of the immune response and a key function is marking
microbial and dying host cells for elimination.
To ensure the
systems» stability, countermeasures may be required to avoid development
of highly resistant, adapted microorganisms, and a complete loss
of microbial diversity.
«There's tons
of questions around just how this whole
system might control
microbial populations in the gut, which have increasingly been shown to be important in obesity and diabetes, and all sorts
of human conditions.»
The hallmark
of vertebrate immune
systems is their ability to «remember» an infection and mount specific attacks against
microbial invaders the next time they come knocking.
About 30 years ago, scientists found a link between MS and certain variants in the major histocompatibility complex (MHC), a cluster
of genes that help the immune
system distinguish between the body's own proteins and those
of microbial invaders.
The immunologist at the U.S. National Institute
of Allergy and Infectious Diseases proposed that alarm signals released from injured and dying cells can kick our immune
system into high gear even when no
microbial threat is evident.
«Mining sequence data in DOE JGI's Integrated
Microbial Genomes & Microbiomes
system, which houses thousands
of metagenomes, allowed us to find evolutionary relatives
of our Klosneuvirus,» Schulz said.
Nicholson (2006) has long been a proponent
of the application
of systems analysis to diagnostics and therapeutics, focusing, in particular, on the metabolome and its environmental (including
microbial) modulation.
Divergent assemblage patterns
of abundant and rare
microbial sub-communities in response to inorganic carbon stresses in a simultaneous anammox and denitrification (SAD)
system — Duntao Shu, Bioresource Technology
Assessing the origin
of bacteria in tap water and distribution
system in an unchlorinated drinking water
system by SourceTracker using
microbial community fingerprints — Gang Liu — Water Research