The group solicits fecal samples from people all around the world in an effort to build a comprehensive library
of microbiome communities.
While the UniFrac analyses we performed suggest independent associations between microbiome composition and both delivery mode and feeding method, the substantial overlap between the communities defined by both factors suggests that there are other important drivers
of microbiome community composition that remain to be identified in future analyses.
Not exact matches
Fermented foods are having a big moment, prompted in part by a flood
of new research on the human
microbiome — the ecological
community of microorganisms living in the human body — and the benefits
This
community of bacteria is often referred to as a
microbiome, and your whole system can go out
of whack if your
microbiome is off - balance.
Your baby's gut and
microbiome are especially delicate — shifting
communities of microbes that are still finding their tribe and carving out their home in your baby's digestive tract.
The midwifery and natural childbirth
communities are abuzz with news
of the premiere
of Microbirth, a movie based on purported new medical discoveries about childbirth and the
microbiome, the bacteria that normally live within the human intestines.
These complex sugars are indigestible by the infant but appear to play a powerful role in shaping an infant's gut
microbiome, the fine - tuned
community of trillions
of microbial cells that, again, scientists are only beginning to understand.
Previous studies have shown that a high fat maternal diet during gestation and lactation has a long - term impact on the infant's gut
microbiome (the
community of bacteria living inside the human gut.)
Association between breast milk bacterial
communities and establishment and development
of the infant gut
microbiome.
We characterized the intestinal
microbiome of 102 6 - week - old infants and observed independent associations between stool microbial
community composition, mode
of delivery, and feeding method.
Overall stool
microbiome community composition was characterized using generalized UniFrac analysis.30 Controlling for the effects
of feeding method, delivery mode was strongly associated with infant gut
microbiome composition (P <.001; Q <.001)(Figure 1A).
Although a few previous studies have found associations between infant feeding and intestinal
microbiome composition,9 - 12, 14 to our knowledge, none has examined the relative contribution
of combination feeding (breast milk and formula) alongside exclusive formula or breastfeeding to overall microbial
community composition.
In pairwise comparisons
of the 3 feeding methods, exclusive breastfeeding was associated with a
microbiome community distinct from that
of infants who were either exclusively formula fed (P =.04; Q =.05) or fed a combination
of breast milk and formula prior to stool collection (P =.02; Q =.04).
There have been no long - term longitudinal studies
of the effects
of early feeding method on the
microbiome, but early feeding has the potential for lasting effects on microbial
community structure, 32 and these effects may be one mechanism for the health benefits
of breastfeeding on childhood and lifelong health.
This is the seeding
of the baby's
microbiome, the
community of «good» bacteria that we carry with us throughout our lives.
In this latest advance reported in PNAS, the Wyss team showed that the human gut - on - a-chip's unique ability to co-culture intestinal cells with living microbes from the normal gut
microbiome for an extended period
of time, up to two weeks, could allow breakthrough insights into how the microbial
communities that flourish inside our GI tracts contribute to human health and disease.
Coauthor Alan Wolfe, PhD, Professor
of Microbiology and Immunology at Loyola, overturned that dogma when his laboratory discovered the female urinary
microbiome, and he has been at the forefront
of isolating and characterizing individual bacterial species from this novel bacterial
community.
During this developmental time, the bacterial
communities covering the animal's surface change radically, until a stable composition
of the
microbiome finally forms.
Scientists attribute this heft to different
microbiomes — the
communities of microorganisms that live in and on the body — in the C - section group.
The study adds to knowledge
of how microbes colonize our skin and how much our microbial
communities — or
microbiomes — change when we contact other people or surfaces, whether it's a doorknob at home or medical equipment in a hospital.
The
microbiome is like a fingerprint: every person's
community of microbes is complex and unique.
The findings add strength and precision to a growing body
of evidence that the makeup
of bacterial
communities in the vagina — the vaginal
microbiome — may increase or decrease HIV risk for women, depending on which bacteria are there.
Shifts in the balance
of the human
microbiome — the microbial
communities that call our bodies home — underlie persistent inflammatory disorders, chronic non-healing wounds, and scar formation.
«The more we know about the microbial
communities in a given environment, the more likely it is we can reshape them to improve environmental and human health,» said senior author Rob Knight, PhD, professor
of pediatrics and computer science and engineering, and director
of the Center for
Microbiome Innovation at UC San Diego.
(Gut bacteria are part
of the
microbiome, the larger
community of microbes that exist in and on the human body.)
Understanding more about the interactions between the microbial
communities — also called «
microbiomes» — in the biocrusts and their adaptations to their harsh environments could provide important clues to help shed light on the roles
of soil microbes in the global carbon cycle.
The plant's root
microbiome is the unique
community of micro-organisms living in and on plant roots.
By tracking changes to the
microbiome through fecal samples, Alm hoped to learn more about how daily activities such as diet, sleep and exercise could be linked to changes in these
communities of microorganisms.
Large - scale genome sequencing efforts, like the Human
Microbiome Project, have focused on the
community of microorganisms that live in the human gut.
The research on the wild bee
microbiome, or the
community of microorganisms that live in the bee, follows similar work on the human
microbiome that has surged in popularity in the past decade.
Collectively known as the
microbiome, this
community may play a role in regulating one's risk
of obesity, asthma and allergies.
«Ochman and colleagues show that human evolution was accompanied by both a rapid divergence
of the
microbiome from the
microbiome of apes, and a drastic loss
of diversity
of the microbial
community,» says Thomas Bosch
of the Christian Albrechts University in Kiel, Germany.
University
of California, Riverside researchers investigated whether
microbiomes — microbial
communities that are associated with larger hosts — might play a role.
In the handful that developed T1D during this period, the team observed a 25 % drop in
community diversity (in other words, in the number
of distinct species present in the
microbiome) one year prior to the onset
of the disease.
«Since we found previously that the gut
microbiome — the
communities of bacteria and other microbes living there — can influence liver disease risk, we wondered what effect gastric acid suppression might have on the progression
of chronic liver disease.
This microbial
community was very diverse, similar to other mammalian ocular
microbiomes but with an unusually high representation
of bacteria from a family not observed in other mammals.
Couples who enjoy at least nine «intimate kisses» a day are also more likely to have similar
communities of bacteria in their mouths (
Microbiome, doi.org/w7g).
Those inhabiting the human body have received increased attention in recent years, owing to a greater appreciation
of the interrelated nature
of humans and their
microbiome, an improved understanding of microbial ecology, and an unprecedented ability to detect fine - scale microbial community changes with high - throughput sequencing technology (Human Microbiome Project Consorti
microbiome, an improved understanding
of microbial ecology, and an unprecedented ability to detect fine - scale microbial
community changes with high - throughput sequencing technology (Human
Microbiome Project Consorti
Microbiome Project Consortium, 2012).
We believe that to be successful,
microbiome research will require a coordinated effort across the international
community of biologists, chemists, geologists, mathematicians, physicists, computer scientists and clinical experts.
Several reasonable explanations arise given these results: (1) all players were exercising, and exercise produces predictable changes in skin habitat conditions that are likely to affect bacterial
communities over time; (2) players were acquiring microbial transients from the built environment; and (3) players were coming into repeated physical contact with their teammates and those from opposing teams, often using the sampled area
of their upper arms, and potentially sharing portions
of their skin
microbiomes.
For instance, the Human
Microbiome Project (HMP)(Turnbaugh et al, 2007; Peterson et al, 2009; Huttenhower et al, 2012) and MetaHIT (Qin et al, 2010) have generated maps
of bacterial species abundances throughout the human body, reference genomes, and catalogs
of more than 100 million microbial genes assembled from shotgun sequencing
of in vivo
communities.
A holistic understanding
of the role
of Earth's microbial
community and its genome — its
microbiome — in the biosphere and in human health is key to meeting many
of the challenges that face humanity in the twenty - first century, from energy to infection to agriculture.
Future studies will characterize other members
of the
microbiome to understand how endometriosis alters these
communities.
Actinobacterial
community structure in the Polar Frontal waters
of the Southern Ocean
of the Antarctica using Geographic Information System (GIS): A novel approach to study Ocean
Microbiome — P. Sivasankar — Data in Brief
«Our goal is to discover what microbial
communities exist in different parts
of the human body and to explore how these
communities change in the presence
of health or disease,» said National Human Genome Research Institute Director, Francis S. Collins, M.D., Ph.D., co-chair
of the Human
Microbiome Project Implementation Group.
Eoin Brodie seeks to reverse engineer naturally occurring
microbiomes to understand the functional roles
of the microorganisms within them and how their interactions with one another and the environment create stable microbial
communities.
«I view the Kavli
Microbiome Ideas Challenge as a catalyst, a program that brings new approaches and new people into the field to rapidly increase our understanding
of microbial
communities» functions and mechanisms,» said Tim Donohue, Past President, ASM.
October 28, 2015 — A consortium
of 48 scientists from 50 institutions in the United States has called for an ambitious research effort to understand and harness
microbiomes — the
communities of microorganisms that inhabit ecosystems as varied as the human gut and the ocean, to improve human health, agriculture, bioenergy, and the environment.
While many people have become familiar with the
community of microbes that live on us, with us, and within us — the human
microbiome — the soil
microbiome is lesser known but crucial for the fate
of our planet.
«The recent emergence
of faster and cost - effective sequencing technologies promises to provide an unprecedented amount
of information about these microbial
communities, which in turn will bolster the development and refinement
of analytical tools and strategies,» said NIAID Director Anthony S. Fauci, M.D., co-chair
of the Human
Microbiome Project's Implementation Group.