Sentences with phrase «of microbiome diversity»

Researchers are finding this lack of microbiome diversity plays a role in many chronic health and brain disorders, including depression and autoimmune diseases such as Hashimoto's hypothyroidism.

Not exact matches

And what we found is that, in patients who responded to the treatment, they actually had a much higher diversity of bacteria in their gut microbiomes compared to non-responders.»
A lack of gut microbiome diversity has been linked to type 2 diabetes, and increasing this diversity can help keep diseases like diabetes and heart disease away.
It also provides low - FODMAP prebiotic sources in order to support the diversity of the gut microbiome.
Participant Characteristics and Variability and Diversity of the Early Neonatal Microbiome
A new Canadian study finds that the microbiome of infants born via unplanned Cesarean had increased bacterial richness and diversity, more similar to that of vaginally born infants than planned Cesarean [10].
They analyzed stool samples collected from children in the urban slums of Dhaka, Bangladesh, and determined that children with more severe infections had less diversity in their gut microbiome.
The investigators examined 181 bacterial genomes taken from the female urinary microbiome, which Dr. Putonti said were representative of that microbiome's phylogenetic diversity.
«This is just the first in what will likely be numerous studies into the phage diversity of the urinary microbiome,» said Dr. Putonti.
When on the low - fiber diet, animals showed a decrease in the diversity of their microbiome, with 60 percent of the bacteria species plummeting in numbers compared with their high - fiber friends.
Jackson's work on microbial diversity caught the attention of Seed, who was already interested in the microbiome in the guts of preterm infants but who did not have a background in ecology.
The Duke study is just one of many projects begun in the past five years that use genetic sequencing to explore how the diversity of the microbiome impacts our health.
As Venkateswaran and colleagues explain online today in Microbiome, they relied on state - of - the - art «deep - sequencing» machines, which are better able to assess diversity and abundance of organisms than traditional techniques.
Interestingly, the Americans lacked some of the strains of bacteria found in Malawians — and in gorillas and chimps — which fits with the general reduction in gut microbiome diversity that has been observed in people in industrialized societies, perhaps because of changes in diet and the use of antibiotics.
Interestingly, these semi-captive animals» microbiomes fell right in between those of the wild and captive doucs, further supporting they hypothesis that lower plant consumption causes loss of microbial diversity.
In samples from HIV - infected untreated men, semen microbiome diversity was markedly reduced, and the relative abundance of the more common bacterial groups differed.
«Greater diversity of bacteria in the gut microbiome is associated with both a higher response rate to treatment and longer progression - free survival,» said study leader Jennifer Wargo, M.D., associate professor of Surgical Oncology at MD Anderson.
The suggested focus should be in building the resilience of society and maintaining diversity in the «global microbiome» — only a fraction of which causes human or animal disease.
«Ochman and colleagues show that human evolution was accompanied by both a rapid divergence of the microbiome from the microbiome of apes, and a drastic loss of diversity of the microbial community,» says Thomas Bosch of the Christian Albrechts University in Kiel, Germany.
«Our findings point to two potential impacts from additional research — analyzing the diversity and composition of the microbiome to predict response to immunotherapy and modulating the gut microbiome to enhance treatment,» said Wargo, senior researcher on the project and co-leader of the Melanoma Moon Shot ™, part of MD Anderson's Moon Shots Program ™ to reduce cancer deaths by accelerating development of therapies from scientific discoveries.
In the handful that developed T1D during this period, the team observed a 25 % drop in community diversity (in other words, in the number of distinct species present in the microbiome) one year prior to the onset of the disease.
As Mani Subramanian, Summers's adviser, points out, 90 % of the cells in our body are bacterial, and research into the human microbiome, our total complement of bacteria, has revealed that we are veritable rainforests when it comes to bacterial diversity.
«Reduction in dietary diversity impacts richness of human gut microbiota: Dietary diversity necessary for a healthy gastrointestinal microbiome
Despite the importance of our skin microbiota, we still know very little about what shapes the distribution and diversity of the skin microbiome.
For instance, one priority could be to increase the number and diversity of people sampled in studies of the human microbiome.
Pollard, senior investigator at the Gladstone Institutes and professor of epidemiology and biostatistics at the University of California, San Francisco, delivered a presentation titled «Estimating Taxonomic and Functional Diversity in Shotgun Metagenomes» during an invited session focused on statistics, the microbiome and human health.
This has led to an explosion of knowledge about microbiomes, as scientists use these tools to catalog the stunning diversity of species that inhabit the planet and study their genes.
«We determined that the uterine microbiome is not simply a subset of the vaginal microbiome and that microbial diversity increased with stage III endometriosis,» said ORNL's Melissa Cregger, lead author of a pilot study published in Reproductive Immunology.
Through the Earth Microbiome Project, he seeks to characterize the microbial diversity of our planet.
Impaired diversity of the lung microbiome predicts progression of idiopathic pulmonary fibrosis — Youhei Takahashi, Respiratory Research
Professor Segal's research has two major directions 1) Gene regulation — using quantitative and computational models to understand how DNA sequence variation among human individuals generates phenotypic diversity 2) Microbiome and Nutrition — understanding how the microbial composition of individuals affect their physiology and health.
Low dose brain estrogen prevents menopausal syndrome while maintaining the diversity of the gut microbiomes in estrogen - deficient rats — Sunmin Park — American Journal of Physiology - Endocrinology and Metabolism
Conversely, the species diversity of the vaginal microbiome of HPV - positive women tends to be higher with significantly less Lactobacillus spp..
The results indicate that the enormous bacterial diversity residing in natural soils may account for the stability of the plant - microbiome relationship.
The study, published July 21, 2016, in Scientific Reports, also showed significant changes in the gut microbiome after antibiotic treatment, suggesting the composition and diversity of bacteria in the gut play an important role in regulating immune system activity that impacts progression of Alzheimer's disease.
Human gut microbiome ** Competitively Selected Donor Fecal Microbiota Transplantation: Butyrate Concentration and Diversity as Measures of Donor Quality.
Plant, root, and soil microbiome Photoautotrophic organisms control microbial abundance, diversity, and physiology in different types of biological soil crusts.
For example, lower diversity of the gut microbiome has been associated with obesity and inflammatory bowel disease (IBD), and higher diversity in the vagina with bacterial vaginosis.
There is high diversity of studies, with a high abundance of gut microbiome studies, a few publications on fecal transplant, and some very interesting early life / pregnancy / mother - infant science.
Our understanding of the diversity and roles of these microbiomes is limited, a fact that led the White House Office of Science and Technology Policy to launch the National Microbiome Initiative last year.
Ken is currently involved with several research projects, including the US - based eXtreme Microbiome Project (XMP), as well as evaluating emerging technologies that can be used to profile the diversity of microbial communities.
In the proposed partnership between Addis Ababa University (AAU) and J. Craig Venter Institute (JCVI), the objective is to build genomics capacity at AAU and to apply newly developed skills towards understanding the relationships of active TB disease with Mtb strain type diversity and host components such as the human respiratory microbiome and protein - based analysis of immune responses in the respiratory tract.
As shown in FIG. 1A, a first method 100 for diagnosing and treating an autoimmune condition comprises: receiving an aggregate set of samples from a population of subjects S110; characterizing a microbiome composition and / or functional features for each of the aggregate set of samples associated with the population of subjects, thereby generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects S120; receiving a supplementary dataset, associated with at least a subset of the population of subjects, wherein the supplementary dataset is informative of characteristics associated with the autoimmune condition S130; and transforming the supplementary dataset and features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset into a characterization model of the autoimmune condition S140.
A healthy skin microbiome should contain a diversity of bacteria including ammonia - oxidizing bacteria, which convert ammonia in sweat to beneficial nitrates.
Macmillan, 2014; Holler, E., et al. «Metagenomic analysis of the stool microbiome in patients receiving allogeneic stem cell transplantation: Loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal graft - versus - host disease.»
Here is just one such study, which although small in sample size was able to demonstrate that a low residue diet (LRD, aka low fiber diet) resulted in a decrease in microbiome diversity among patients with Crohn's disease, which is indicative of gut dysbiosis..
Is it safe to say, as a general take away, that optimizing the diversity of your microbiome is positively correlated with optimizing your immunity and overall health?
As shown in FIG. 1A, a first method 100 for diagnosing and treating an autoimmune condition comprises: receiving an aggregate set of samples from a population of subjects Silo; characterizing a microbiome composition and / or functional features for each of the aggregate set of samples associated with the population of subjects, thereby generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects S120; receiving a supplementary dataset, associated with at least a subset of the population of subjects, wherein the supplementary dataset is informative of characteristics associated with the autoimmune condition S130; and transforming the supplementary dataset and features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset into a characterization model of the autoimmune condition S140.
So, drinking the alcohol and changing the diversity of their microbiome in a way that was not beneficial and caused the mice to have a worse outcome when they did become sick.
Good fibers called arbinogalactans from carrots, onions, radishes & jicama help to feed the gut microbiome and improve the diversity of beneficial species.
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