Sentences with phrase «of microbiome studies»

By developing a computational shortcut to rapidly estimate genome size using statistical modeling, Dr. Pollard's team has been able to improve the accuracy of microbiome studies.

Not exact matches

Some small studies have suggested that synbiotics could provide benefits to a range of other conditions influenced by the gut microbiome as well, including obesity, diabetes, and non-alcoholic fatty liver disease, but larger - scale clinical trials focusing on each of those conditions are needed.

«It also brings in the question of diet,» says Wargo, who is now working on new clinical studies on the microbiome with the Parker Institute for Cancer Immunotherapy.

The study provides another example of the role of the microbiome — the collection of microbes found in and on the body — in health and disease.

DuPont Nutrition & Health (DuPont) released the findings of a research study showing that DuPont ™ Danisco ® Litesse ® Ultra ™ polydextrose alters the gut microbiome.

Even in IBD patients, who have a very messed up microbiome (a finding of the American Gut data), the benefits of antioxidant therapy is well documented (see below studies).

I didn't see any evidence (1) actually connecting the former to the latter, (2) that the differences at birth are lasting, (3) that the purported diseases associated with the microbiome in adulthood are the same ones associated with c - section (the author cites obesity, but we know that those observational studies re: c - section and obesity are deeply flawed by confounding)(4) that the «microbiotic» benefit of vaginal birth exists regardless of maternal health and matenral microbiome.

Previous studies have shown that a high fat maternal diet during gestation and lactation has a long - term impact on the infant's gut microbiome (the community of bacteria living inside the human gut.)

In this study, researchers found that specific changes to maternal diet in the same woman (changing fat versus carbohydrate consumption, or changing consumption of specific sugars), is associated with changes in both the milk microbiome and human milk oligosaccharide (a carbohydrate) composition.

«Further studies are needed to delineate if specific changes in maternal diet during breast - feeding alter the infant gut microbiome and to determine if this results in any health consequences for the infant,» said Kristen Meyer, in the Department of Obstetrics and Gynecology at Baylor College of Medicine and the presenter of the study at the SMFM annual conference.

Given that these two components of breast milk have the potential to alter the gut microbiome of breast - feeding infants, the results of the study suggest that development of the infant gut microbiome may be affected in part by what the mother eats during breastfeeding.

In a study to be presented Thursday, Jan. 26, in the oral plenary session at 1:15 p.m. PST, at the Society for Maternal - Fetal Medicine's annual meeting, The Pregnancy Meeting ™, researchers with Baylor College of Medicine, Houston, Texas and University of California, San Diego, La Jolla, California, will present their findings on a study titled, Maternal Diet Structures the Breast Milk Microbiome in Association with Human Milk Oligosaccharides and Gut - Associated Bacteria.

We evaluated the associations between the composition of the 6 - week intestinal microbiome and both delivery mode and feeding method in 102 full - term, appropriately grown infants enrolled in the New Hampshire Birth Cohort Study.

To our knowledge, our study was the first to examine the contribution of delivery mode to infant intestinal microbiome composition in association with that of another important predictor of microbiome composition, infant diet.

In addition, many studies do not take into account the complex interaction of different fatty acid subtypes, such as omega - 3 and omega - 6 fatty acids, on gut inflammation as well as their effect on the intestinal microbiome.

Although a few previous studies have found associations between infant feeding and intestinal microbiome composition,9 - 12, 14 to our knowledge, none has examined the relative contribution of combination feeding (breast milk and formula) alongside exclusive formula or breastfeeding to overall microbial community composition.

An emerging body of literature in adults has begun to establish clear associations between gut microbiome composition and a wide range of health outcomes.1 - 6 In contrast, comparatively little is known about the gut microbiome in infants and children, the exposures that shape it, and its lifelong health effects.7 Although limited in their size and scope, a number of studies have established associations between intestinal microbiome profiles in infants, delivery mode, and / or breast milk exposure.8 - 15 These factors both have long - term health consequences.

The contribution of the mode of delivery to the infant microbiome has been evaluated.13, 15,24 However, no study has examined the effects of delivery mode and breastfeeding following adjustment for the other, and, to our knowledge, there are few data on the effects of combination feeding (feeding breast milk and formula together).

In a previous study of 24 healthy women, vaginal microbiome composition became less diverse between the second and third trimesters of pregnancy and just before delivery was enriched with Lactobacillus species, likely contributing to vertical transmission of these bacteria during vaginal birth.21 In a study of 10 newborns in Venezuela, within hours of delivery, the intestinal tracts of infants born vaginally were colonized by Lactobacillus and Prevotella, whereas infants delivered operatively acquired bacteria present on the mother's skin and the hospital environment, such as Staphylococcus, Proprionibacterium, and Corynebacterium.15 Quiz Ref ID Our findings, based on a large group of 6 - week - old infants, indicated that Lactobacillus also contributes to the microbial environment of the gut but to a lesser extent than Bifidobacteria, Bacteroides, and Streptococcus.

It would be interesting to see studies about the seeding of microbiome in infants who are born via cesarean section.

A new Canadian study finds that the microbiome of infants born via unplanned Cesarean had increased bacterial richness and diversity, more similar to that of vaginally born infants than planned Cesarean [10].

There have been no long - term longitudinal studies of the effects of early feeding method on the microbiome, but early feeding has the potential for lasting effects on microbial community structure, 32 and these effects may be one mechanism for the health benefits of breastfeeding on childhood and lifelong health.

Oligosaccharides in breast milk are thought to promote Bifidobacterium growth, 35 and decreased Bifidobacterium in infancy has been found to be associated with an increased risk for being overweight at age 10 years.36 Many formulas are supplemented with prebiotics such as short - chain galacto - oligosaccharides and long - chain fructo - oligosaccharides that increase the overall representation of Bifidobacterium in the microbiome of formula - fed infants, and similar to breast milk, promote lactate and short - chain fatty acid prevalence in the infant gut (reviewed in the study by Oozeer et al37).

A research study released in May, 2017 found that the bacteria found in mother's milk and areolar skin seed the infant gut and profoundly influence the development of infant microbiome.

«The study advances our understanding of how the gut microbiome develops early in life,» Thompson said, «which is clearly a really important time period for a person's current and future health.»

Although the vast majority of research on the gut microbiome has focused on bacteria in the large intestine, a new study — one of a few to concentrate on microbes in the upper gastrointestinal tract — shows how the typical calorie - dense western diet can induce expansion of microbes that promote the digestion and absorption of high - fat foods.

«The newborn mice inherited a very altered, skewed population of microbes,» said Eugene B. Chang, MD, Martin Boyer Professor of Medicine at the University of Chicago, Director of the Microbiome Medicine Program of the Microbiome Center, and senior author of the study, published this week in the journal Cell Reports.

Animal studies have started to show that the microbiome, from its staging ground in the bowel, can influence the development of its host's brain.

The first microbiome study of the penis offers some clues as to why removing foreskin cuts the risk of HIV infection in circumcised men

Ancient DNA analysis of microbiomes is in the early stages, but numerous studies of the microbiomes of today's traditional societies hint at what researchers may find.

«This is just the first in what will likely be numerous studies into the phage diversity of the urinary microbiome,» said Dr. Putonti.

While the study looked only at the ability of fish to exchange microbes, it suggests that microbiome variation among different people might also be due to the movement of microbes, and that when people come together for a class or a meeting, for example, they may depart with a microbiome that is somewhat different than when they entered, Bohannan said.

Dr Luis Pedro Coelho, corresponding author of the study, commented: «We found many similarities between the gene content of the human and dog gut microbiomes.

«Until now, use of traditional culture methods and even more sophisticated organoid cultures have prevented the microbiome from being studied beyond one or two days.

«Cultural revolution in the study of the gut microbiome: Human gut - on - a-chip technology used to co-culture gut microbiome, human intestinal cells could lead to new therapies for inflammatory bowel diseases.»

«This technology enables one to study in an isolated and controlled manner the complexity of the microbiome and the role different microbial species play in health and disease.

Even the new studies clashed somewhat: Unlike the UCSF study, the German research found no major differences between the overall microbiomes of twins with and without MS. Finally, mouse models of MS are not perfect mimics of the human disease, and mouse immune systems aren't identical to people's.

The study shows that changes to the microbiome aren't just transient, says Peter Turnbaugh, a microbiologist at the University of California at San Francisco.

Five years ago, Tim Spector of Kings College London attended a presentation of the results of a study in twins that suggested a person's genes don't affect their microbiome.

The researchers did a small study of existing genetic data from the human skin microbiome and estimate that 20 percent of the human population have S. epidermidis strains that make 6 - HAP on their skin, Gallo says.

Treatment implications were examined in a series of human studies that demonstrated similar reductions in the microbiome in participants suffering from both major depression and bipolar disorder.

Published last week in Cell, a study by Santamaria and Kathy McCoy, PhD, from the University of Calgary's Cumming School of Medicine (CSM) reveals a new mechanism in the gut microbiome that regulates pro- and anti-inflammatory cells.

That's the tantalizing finding from a new study published today that reveals a way that mice — and potentially humans — can control the makeup and behavior of their gut microbiome.

In a related study also published today in PNAS, immunologists led by Gurumoorthy Krishnamoorthy and Hartmut Wekerle of the Max Planck Institute of Neurobiology in Martinsried, Germany, examined the gut microbiomes of 34 sets of identical twins, aged 21 to 63, in which only one twin had MS.. They found that Akkermansia was slightly but significantly more abundant in MS patients than in their healthy twins.

The study also gives the researchers a chance to understand how antibiotics impact the formation of the microbiome.

Changes in the composition and activity of the gut microbiome in early life can influence the immune system and these changes might indirectly lead to changes in asthma later in life,» said Dr. Anke Maitland - van der Zee, senior author of the study.

This study that has been ongoing since 2013, Study of the Impact of Long - Term Space Travel on the Astronauts» Microbiome, Microbiome for short, investigates how space travel affects the human immune system and an individual's microbiome, which is the collection of microbes that live in and on the human body at any given study that has been ongoing since 2013, Study of the Impact of Long - Term Space Travel on the Astronauts» Microbiome, Microbiome for short, investigates how space travel affects the human immune system and an individual's microbiome, which is the collection of microbes that live in and on the human body at any given Study of the Impact of Long - Term Space Travel on the Astronauts» Microbiome, Microbiome for short, investigates how space travel affects the human immune system and an individual's microbiome, which is the collection of microbes that live in and on the human body at any gMicrobiome, Microbiome for short, investigates how space travel affects the human immune system and an individual's microbiome, which is the collection of microbes that live in and on the human body at any gMicrobiome for short, investigates how space travel affects the human immune system and an individual's microbiome, which is the collection of microbes that live in and on the human body at any gmicrobiome, which is the collection of microbes that live in and on the human body at any given time.

Earlier studies have linked the human microbiome — that is, the collection of microbes living in and on the human body — to a variety of health conditions, but little is known about the role of the penile microbiome as it relates to men's health.

Managing the microbiome instead of pummeling it with antibiotics has produced impressive results in chicken and mice studies, pointing the way not just to future human treatments but also to a healthier food supply.

The Duke study is just one of many projects begun in the past five years that use genetic sequencing to explore how the diversity of the microbiome impacts our health.