We recorded neural population activity with arrays
of microelectrodes implanted in the PPC of a tetraplegic subject.
To investigate the direct impact of VTA activation on primate behavior, the research team used high - resolution magnetic resonance imaging to guide the placement
of microelectrodes within the VTAs of macaque monkeys.
Not exact matches
At the same time, the activity
of hundreds
of nerve cells was measured with so - called
microelectrode arrays.
Julian Dindas, a PhD student at Hedrich's department, used
microelectrodes that register the electric voltage
of the root hair's cell membrane, the so - called membrane potential, to study the early responses
of the cell to a hormone pulse.
What's more is that each
microelectrode array is made up
of eight «tines,» each with eight
microelectrodes which can record from a total 64 subregions
of the brain at once.
In a new study by Flesher et al.,
microelectrode arrays were implanted into the primary somatosensory cortex
of a person with spinal cord injury and, by delivering current through the electrodes, generated sensations
of touch that were perceived as coming from his own paralyzed hand.
In addition to inflammation, previous
microelectrode brain implants made
of silicon or microwire have caused neuronal death and glial scarring, which is damage to connective tissue in the nervous system.
Researchers at the University
of Southern California Viterbi School
of Engineering have developed thin, flexible polymer - based materials for use in
microelectrode arrays that record activity more deeply in the brain and with more specific placement than ever before.
In addition, the polymer - based material, called Parylene C, is less invasive and damaging to surrounding cells and tissue than previous
microelectrode arrays comprised
of silicon or microwires.
Also, the team plans to create devices with even higher density, including a double - sided
microelectrode array with 64 electrodes per tine instead
of eight — making for a total
of around 4,000 electrodes placed in the brain at once.
Using
microelectrodes, the researchers recorded the electrical activity
of pheromone - sensitive interneurons in male American cockroaches that relay signals
of female - producing sex pheromones in the antennal lobe (functional homolog to the mammalian olfactory bulb) to higher - order centers.
Researchers are probing the brain with increasingly powerful tools, including superfast magnetic resonance imagers and
microelectrodes that can detect the murmurs
of individual brain cells.
The surface
of the chip is covered with
microelectrodes and the chip is connected to a power source, with the power converted to high - frequency sound waves.
The device, part
of the Lab's iCHIP (in - vitro Chip - Based Human Investigational Platform) project, simulates the central nervous system by recording neural activity from multiple brain cell types deposited and grown onto
microelectrode arrays.
More than a decade ago
microelectrode studies
of rats and monkeys revealed place cells that respond when the animals move to a particular spot in a maze.
Protruding from the end
of each macroelectrode are as many as 10 flexible
microelectrodes that can detect the pulses
of individual neurons.
These «intracortical» implants contain 96
microelectrodes that penetrate one to 1.5 millimeters into parts
of the motor cortex that control arm movements.
Students in courses routinely record the activity
of nerves using a variety
of extracellular amplifiers, and they record intracellularly from individual neurons using
microelectrodes.
Thin - film
microelectrode arrays produced at Lawrence Livermore National Laboratory (LLNL) have enabled development
of an automated system to sort brain activity by individual neurons, a technology that could open the door to recording and analyzing unprecedented amounts
of neural signals over time...
But the number
of neurons at a time with which
microelectrode arrays can interface must be increased several-fold while making sure the scale - up does not cause damage to brain tissue.
Linsenmeier et al. [1] measured intraretinal PO2 with
microelectrodes in cats with long - standing diabetes and concluded that the retina was hypoxic in the early stages
of retinopathy.
In a recent publication in the Journal
of the American Chemical Society, researchers from Dynamic Biosensors and the Kurt - Schwabe - Institut Meinsberg have demonstrated the persistent electrical actuation
of a large DNA - origami nanostructure on a gold
microelectrode.
Dec. 12, 2017 - Thin - film
microelectrode arrays produced at Lawrence Livermore National Laboratory (LLNL) have enabled development
of an automated system to sort brain activity by individual neurons, a technology that could open the door to recording and analyzing unprecedented amounts
of neural signals over time...
Through «heart - on - a-chip» technology — modeling a human heart on an engineered chip and measuring the effects
of compound exposure using
microelectrodes — Lawrence Livermore researchers hope to ensure potentially lifesaving new drugs are safe and effective while reducing the need for human and animal testing.
Through «heart - on - a-chip» technology — modeling a human heart on an engineered chip and measuring the effects
of compound exposure on functions
of heart tissue using
microelectrodes — Lawrence Livermore National Laboratory (LLNL) researchers hope to decrease the time needed for new drug trials and ensure potentially lifesaving drugs are safe and effective while reducing the need for human and animal testing.
Using
microelectrodes to monitor individual neurons in the brains
of owl monkeys, he found that the somatosensory cortex has a complete topographical «map»
of the entire body surface, in which adjacent areas
of the map responded to body parts that were next to one another, such as the fingers.
Microelectrode measurements and pharmacological inhibitor studies carried out on larval stages demonstrated that maintenance
of alkaline gastric pH represents a substantial energy sink under acidified conditions that may contribute up to 30 % to the total energy budget.
Vahidi, N., Hirabayashi, M., Mehta, B, Khosla, A., and Kassegne, S., «Bionanoelectronics Platform with DNA Molecular Wires Attached to High Aspect - Ratio 3D Metal
Microelectrodes», ECS Journal
of Solid State Science and Technology 3 (3), Q29 - Q36 2014.