Sentences with phrase «of microfluidic devices»

The work for the making of the microfluidic devices at the BioMEMS Resource Center was supported by the National Institute of Biomedical Imaging and Bioengineering of the NIH (5P41EB002503 - 12).

Prior studies of microfluidic devices have shown that motility of the sperm sample increased to almost 100 percent and morphology of the isolated sperm also was improved after microfluidic sorting.

The researchers produced three types of microfluidic devices.

And compared to other techniques used for assisted reproductive technologies, the use of the microfluidic device resulted in significantly lower rates of DNA damage and improved sperm recovery using this method.

The labelling is for acetylated tubulin in red (identifying all axons), and green for the cell permeable dye calcein, which is only applied on the axonal side of the chambers (top half) and allows the identification of those neuronal cell bodies (bottom half) that have extended axons to the other side of the microfluidic device.

Not exact matches

Prof. Shen and her unit say that, in the future, nanoplasmonic materials may even be integrated with emerging technologies, such as wireless systems in microfluidic devices, allowing users to take readings remotely and thereby minimizing the risk of contamination.

In addition to new understanding of the forces governing microswimmers and their environments, the vortex technique could help prevent biofilms from forming and disrupting microfluidic devices, the authors suggested.

Although some of my research focuses on the development of nanoelectronic devices for life science applications (as well as for telecommunications and radio astronomy), most of my research efforts are based on the use of microfluidic chips (MFCs) with molecular biology.

The discovery helps scientists understand the interaction of microswimmers and could help prevent films from forming in microfluidic devices such as labs - on - a-chip.

The scientists, who come from Princeton and the Georgia Institute of Technology, developed a new microfluidic device that traps and vertically positions tiny objects faster than before.

Wei Wang and Zhi Ping Wang at the A * STAR Singapore Institute of Manufacturing Technology, De Yun Wang at the National University of Singapore and co-workers have now developed the first microfluidic device that enables the direct observation of cilia and their beating frequency on a polyester membrane [1].

As it can take weeks to grow human cells into intact differentiated and functional tissues within Organ Chips, such as those that mimic the lung and intestine, and researchers seek to understand how drugs, toxins or other perturbations alter tissue structure and function, the team at the Wyss Institute for Biologically Inspired Engineering led by Donald Ingber has been searching for ways to non-invasively monitor the health and maturity of cells cultured within these microfluidic devices over extended times.

The research «makes one wonder how far it is possible to go in constructing microfluidic «thinking devices,»» says chemist Irving Epstein of Brandeis University in Waltham, Massachusetts.

Chemist John Pojman of Louisiana State University in Baton Rouge adds that such roving droplets «might be useful as a pumping mechanism for microfluidics, converting chemical energy to mechanical motion in small devices,» such as the microfluidic labs - on - a-chip many researchers are developing as diagnostic machines.

An unlikely vessel could shuttle drops of water around microfluidic devices, giving fine control over chemical reactions

Finding out involves passing a sample of blood through a microfluidic device, in whose tiny channels cancer cells can be captured and identified.

«New portable blood analyzer could improve anemia detection worldwide: The microfluidic device can detect the level of hemoglobin in a whole blood sample using optical absorbance without the chemical preparations of standard processes.»

The lotus plant's magnificent ability to repel dirt has inspired a range of self - cleaning and antibacterial technologies that may also help control microfluidic «lab - on - a-chip» devices

Developed by Assistant Professor Gretchen Mahler and Binghamton biomedical engineering alumna Courtney Sakolish PhD» 16, the reusable, multi-layered and microfluidic device incorporates a porous growth substrate, with a physiological fluid flow, and the passive filtration of the capillaries around the end of a kidney, called the glomerulus, where waste is filtered from blood.

We have designed a microfluidic device in which we can manipulate, lyse, label, separate, and quantify the protein contents of a single cell using single - molecule fluorescence counting.

«There are smaller bioparticles that contain very rich amounts of information that we don't currently have the ability to access in point - of - care [medical testing] devices like microfluidic chips,» says Wardle, who is a co-author on the paper.

Wardle says the combination of carbon nanotubes and multilayer coatings may help finely tune microfluidic devices to capture extremely small and rare particles, such as certain viruses and proteins.

With this method, they created a three - dimensional array of permeable carbon nanotubes within a microfluidic device, through which fluid can flow.

The team integrated a three - dimensional array of carbon nanotubes into a microfluidic device by using chemical vapor deposition and photolithography to grow and pattern carbon nanotubes onto silicon wafers.

With the technology on track for commercialization, Rogers» team, including Dr. Roozbeh Ghaffari, the director of translational science at CBIE, is continuing to test the microfluidic devices in scaled studies with an expanding collection of partners.

The device is a unique example of microfluidics technology, sometimes called a lab - on - a-chip, that pushes water around in microscopic tubes and reservoirs made from the same cellophanelike plastic as soft contact lenses.

Attendees at the astrobiology meeting in Arizona showcased an assortment of high - tech devices for next - generation exploration, ranging from microfluidic «life analyzers» and integrated nucleic acid extractors for studying «Martian metagenomics» to exquisitely sensitive, miniaturized organic chemistry labs for spotting tantalizing carbon compounds and minerals at microscopic scales.

«Faster, smaller, more informative: Device can measure the distribution of tiny particles as they flow through a microfluidic channel.»

Using microfluidic design principles, Liu's group engineered vortices in their device to increase the chance that tumor cells will collide with the surface of the flow channel.

«The next step will be to track a few patients over the course of their treatment, taking several blood draws to see if the data captured by the microfluidic device correlates with the data their medical team is collecting through other methods,» says Liu.

Erkan Tüzel, left, associate professor of physics, biomedical engineering, and computer science at Worcester Polytechnic Institute (WPI), and PhD candidate James Kingsley examine a microfluidic sperm sorting device called SPARTAN (Simple Periodic ARray for Trapping And IsolatioN).

The results were published in the journal Lab on a Chip (Lab on a Chip 17 (19), 3291 - 3299) in an article called: «Magnetic particles assisted capture and release of rare circulating tumor cells using wavy - herringbone structured microfluidic devices.»

Liu has been perfecting a microfluidic device the size of two quarters that has the ability to catch and release circulating tumor cells (CTCs)-- cancer cells that circulate in a cancer patient's blood.

Liu's microfluidic device achieves two key standards by which the success of CTC devices is measured: high capture efficiency and high selectivity.

With the three - year grant, Vanapalli and his collaborators Boyd Butler in the Department of Biological Sciences and Everardo Cobos at the Texas Tech University Health Sciences Center, will build microfluidic devices that mimic blood flow to study how tumor cells move inside capillaries, how they squeeze through tight spaces, whether they are subject to fragmentation and how they become stuck.

The findings, the result of microscopic analysis of bacteria inside microfluidic devices, were made by MIT postdoc Roberto Rusconi, former MIT postdoc Jeffrey Guasto (now an assistant professor of mechanical engineering at Tufts University), and Roman Stocker, an associate professor of civil and environmental engineering at MIT.

«Mammalian fertilization, caught on tape: Using a new microfluidic device called the «IVF chip,» scientists obtain the first images with both high spatial and temporal resolution of the initial steps of fertilization.»

The microfluidic device is the size of a bento box and has a series of cables and pumps that cause media (simulated blood) to flow between wells.

In microfluidic devices, very small and trivial variables can frequently cause a large amount of errors.

The team from the Massachusetts General Hospital plans to use the microfluidic devices in synergy with some more sophisticated molecular biology tools and identify the control factors of cell migration speed.

In an effort to overcome these limitations, a team at the Wyss Institute for Biologically Inspired Engineering led by its Founding Director, Donald Ingber, M.D., Ph.D., had previously engineered a microfluidic «Organ - on - a-Chip» (Organ Chip) culture device in which cells from a human intestinal cell line originally isolated from a tumor were cultured in one of two parallel running channels, separated by a porous matrix - coated membrane from human blood vessel - derived endothelial cells in the adjacent channel.

An automated microscope takes images every 20 minutes at multiple locations in the microfluidic device, and multiple devices at once, allowing for the tracking of dozens of cells in one experiment.

To study this barrier and determine why a lack of blood flow causes it to leak, the researchers built a blood - vessel - on - a-chip model consisting of a channel lined with a layer of human endothelial cells surrounded by extracellular matrix within a microfluidic device, which allowed them to easily simulate and control the flow of blood through a vessel and evaluate the cells» responses.

In their article, the teams describe how they used the process to etch patterns of hollow channels like those used to direct the flow of liquids, such as a blood sample, in a microfluidic device, or lab on a chip.

In this article, his group describes an acoustofluidic rotational manipulation (ARM) method that traps bubbles in a series of small cavities inside a microfluidic device.

Measuring two fundamental properties of surface chemical reactions on the same device means that researchers can be far more confident that biomolecules have been successfully encapsulated within the microfluidic platform.

«These highly elusive 3 - nanometer structures are too small to be captured with other types of liquid biopsy devices, such as microfluidics, due to shear forces that can potentially destroy them,» he noted.

«Liver tissue model accurately replicates hepatocyte metabolism, response to toxins: Microfluidic device may help predict toxic effects of new drugs, study liver disease.»

In order to develop a system that more closely replicates the metabolic differences among hepatocytes, the research team developed a microfluidic device that distributes hormones or other chemical agents across a 20 - to 40 - cell - wide sample of hepatocytes in such a way that the effects on the liver cells vary from one side to the other.

The microfluidic device designed by his team captures cells based on their distinct internal structure — a mechanical analysis instead of the blood chemistry analysis used in conventional medical diagnostic techniques.