Information on island - mainland comparisons
of microsatellite diversity and differentiation was unavailable for island foxes and deer mice.
The use
of microsatellite variation to infer population structure and demographic history in a natural model system
For the remaining 14 samples, a match was nearly perfect, with only one or two
of the microsatellite markers varying, typically by only one repeat unit, as might be expected through microsatellite instability within a pedigree.
Development
of Microsatellite Markers in Autopolyploid Sugarcane and Comparative Analysis of Conserved Microsatellites in Sorghum and Sugarcane, Brandon James, Cuixia Chen, Arthur Rudolph, Kankshita Swaminathan, Jan Murray, Jong - Kuk Na, Ashley Spence, Brandon Smith, Matthew Hudson, Stephen Moose, Ray Ming, Molecular Breeding, doi: 10.1007 / s11032 -011-9651-1, October 14, 2011.
Risk
of Microsatellite - Unstable Colorectal Cancer Is Associated Jointly with Smoking and Nonsteroidal Anti-inflammatory Drug Use
Both cancer types demonstrate a high frequency
of microsatellite instability, where the repair mechanism for DNA is broken, and mutations in POLE, a gene responsible for producing a protein involved in DNA replication and repair.
The unit provides genetic testing services using a combination
of both microsatellite and single nucleotide polymorphism (SNP) panels for characterizing and selecting breeders in a wide variety of inbred mouse strains subsequently used for the generation of congenic animals.
High intake of marine ϖ - 3 polyunsaturated fatty acids (PUFAs) is associated with lower risk
of microsatellite instable (MSI) colorectal cancers (CRCs) but not microsatellite stable (MSS) CRCs, according to a new study published March 25 in the JNCI: Journal of the National Cancer Institute.
In order to detect microsatellites commonly present in the two Acropora species used in the study, the researchers used a process called polymerase chain reaction (PCR), using a pair of flanking DNA sequences that extend to either side
of the microsatellite region.
However, the development
of microsatellite DNA markers remains time consuming, expensive, and labor intensive since the markers are often species specific.
In order to detect microsatellites commonly present in the two Acroporaspecies used in the study, the researchers used a process called polymerase chain reaction (PCR), using a pair of flanking DNA sequences that extend to either side
of the microsatellite region.
Both studies highlight the importance
of microsatellite length in oncogenic function.
So the Kyoto researchers developed a set
of microsatellite markers, short bits of repeated sequences of DNA that tend to evolve very quickly.
Aborted launch
of microsatellite this morning is latest failure for nation's space scientists
That's why a particular pattern
of microsatellites can profile a particular individual — to show, for instance, as Tyler - Smith and Zerjal had done shortly before embarking on their Central Asian work, that Thomas Jefferson had fathered a son by his slave Sally Hemings and that his Y chromosome had been passed down to a man living in Pennsylvania today.
The Microsatellite Center is a high - throughput genotyping laboratory dedicated to mapping monogenic and especially polygenic factors with linkage analysis by using fluorescent detection
of microsatellites.
The beauty
of microsatellites is that they mutate frequently and at a steady pace, enabling scientists to infer from them when human populations first diverged from each other.
The researchers identified a clear set
of microsatellites specific to each breed.
Interestingly, cats from Flinders and Tasman Islands have close affinity, in terms
of microsatellites, with the Cocos Islands.
Not exact matches
Although a variety
of molecular methods are still in use,
microsatellite DNA markers have become the marker
of choice for population studies.
Others, such as a new
microsatellite system aiming to improve measurements
of hurricane intensity and a highly anticipated new computer simulation that forecasts hurricane paths and intensities, are still in the calibration phase.
By examining bits
of DNA called
microsatellites, which mutate rapidly, Goossens was able to trace individual genetic differences back to a common ancestor and estimate the size
of the orangutan population at different times in the past.
In much the same way that forensic scientists compare DNA samples to catch criminals, the New Mexico researchers compared 619 «
microsatellite» positions on genomes, creating a digital evolutionary tree
of the groups.
The population - based study
of 503 people with colon cancer found that 14 percent
of Caucasians and 7 percent
of African - Americans had a genetic marker called
microsatellite instability, or MSI.
They used sequences
of maternally inherited mitochondrial DNA and «
microsatellite genotypes,» or DNA profiles, to both describe the genetic differences and outline migratory connections between both breeding and feeding grounds.
For the new study, which is published today in the Proceedings
of the Royal Society B, Bowman and his colleagues collected samples from 38 L. mariae palms in Palm Valley and 100 L. rigida palms in the Roper, Nicholson, and Gregory rivers and compared the
microsatellite markers.
Extra bases are easily added or lost when the DNA is copied, so the number
of repeats in each
of these stretches, known as
microsatellites, varies widely from one individual to another.
By matching
microsatellite lengths found in acorns against those
of all the adult trees in the stand, Dow was able to identify the father
of each acorn with a high degree
of certainty — if the father was present in the stand.
A team
of scientists led by Aarhus University mapped the migration patterns, centre
of diversity and population structure
of this aggressive fungus using
microsatellite genotyping
of worldwide representative samples.
Funded by the National Zoological Gardens
of South Africa, Rufford's Small Grants for Nature, and the National Geographic Society, Parusnath is developing and testing
microsatellite markers similar to those used in human parentage tests to establish the genetic relatedness
of Sungazers in different populations across the species» distribution.
In the largest study
of its kind to date, researchers used mitochondrial DNA
microsatellites from skin samples gathered from more than 3,000 individual humpback whales across the Southern Hemisphere and the Arabian Sea to examine how whale populations are related to one another, a question that is difficult to answer with direct observations
of whales in their oceanic environment.
A
microsatellite is a short, repetitious sequence
of DNA — CACACACA, for instance — in which the number
of repetitions can change from one generation to the next and often does.
His team sampled 22 bedbug populations from nine states along the U.S. East Coast and examined nine so - called
microsatellites, highly variable pieces
of DNA that are particularly helpful in understanding genetic differences between populations.
The goal was to see if a mother ship
microsatellite could launch smaller daughter ships, with all the satellites capable
of sending magnetic field measurements to Earth.
But the chance that a given
microsatellite will change from, say, 11 CA (cytosine and adenine) repeats to 12 is on the order
of one in a few hundred.
«Our results have revealed and characterized two classes
of GGAA -
microsatellites that suggest unique interactions and distinct regulatory mechanisms for distance - dependent activation and repressions.
«Two classes
of GGAA -
microsatellites in a Ewing sarcoma context: Characterization
of GGAA -
microsatellites provides insight in the role
of noncoding DNA in cancer susceptibility and therapeutic development.»
That data revealed two distinct types
of GGAA -
microsatellites: «promoter - like» (close - range) and «enhancer - like» (long - range).
Further investigation into how EWS / FLI associates with GGAA -
microsatellites to drive transcription was the subject
of a recent study published in Proceedings
of the National Academy
of Sciences.
This characterization contributes insight into EWS / FLI transcription factor biology and clarifies the role
of GGAA -
microsatellites on a global genomic scale.»
According to the study, EWS / FLI binding and gene activation at promoter - like
microsatellites is highly dependent on the length
of GGAA motifs.
The distance between these neighboring sequences, called primers, differs between each individual coral due to the number
of times the
microsatellites are repeated, providing valuable information on the relatedness
of different individuals.
Another breakthrough came a few years later with the discovery
of «
microsatellites», short sequences
of two to four nucleotides.
Microsatellites are a gene mapper's dream: not only are they repeated different numbers
of times in different people, but they are scattered throughout the genome.
After extracting tiny amounts
of ancient DNA from the mummies» bones, the researchers amplified 16 short tandem repeats (short sequences in the DNA that create a genetic fingerprint) and eight polymorphic
microsatellites (hereditary molecular markers) to testable quantities using techniques commonly employed in criminal or paternity investigations.
In 2017, the U.S. Food and Drug Administration (FDA) approved the cancer drug Keytruda (pembrolizumab) for a range
of solid tumors that are either
microsatellite instability - high (MSI - H) or mismatch repair deficient (dMMR).
For the study, an international team
of researchers based at institutions in Spain, the United States, Canada and Australia used mitochondrial DNA and
microsatellite genotypic data to investigate the levels
of genetic variation and to reconstruct the history
of the invasions.
So the scientists caught blackcaps when the birds returned to Germany in the spring and sequenced short stretches
of their genomes called
microsatellites.
It's one
of the most promising techniques in weather forecasting in a generation, and is already used on government - owned constellations, including the six
microsatellites that were launched in the Constellation Observing System for Meteorology, Ionosphere, and Climate (COSMIC), a joint project between NOAA and Taiwan.
The National Institute
of Information and Communications Technology (NICT, President: Hideyuki Tokuda, Ph.D.) developed the world's smallest and lightest quantum - communication transmitter (SOTA) onboard the
microsatellite SOCRATES.