Our experimental and theoretical analysis draws upon nuclear magnetic resonance (NMR) spectroscopy, a variety
of microscopy techniques such as transmission electron microscopy, computation tools such as the NWChem for high - performance computational chemistry as well as supercomputers, and other tools.
It also adds details to the descriptions
of the microscopy techniques for which the Nobel was awarded.
Then, they looked at pairs of proteins in the complex using super-resolution microscopy — a special kind
of microscopy technique that can discern much smaller things than a traditional optical microscope can — to systematically identify when each protein disassembled.
This is a close - up of the head region of the Alalcomenaeus fossil specimen with the superimposed colors
of a microscopy technique revealing the distribution of chemical elements in the fossil.
Close - up of the head region of the Alalcomenaeus fossil specimen with the superimposed colors
of a microscopy technique revealing the distribution of chemical elements in the fossil.
Not exact matches
To investigate the nonlinear response
of such plasmonic oligomers, the authors used a novel optical
microscopy technique, which is equipped with polarization - structured beams.
Using a relatively new
microscopy technique called atom probe tomography, their work produced the first - ever three - dimensional maps showing the positions
of atoms critical in the decay process.
Forthcoming workshops cover
techniques as varied as «molecular and genetic tools for the analysis
of medaka and zebrafish development» and «cryo - electron
microscopy and 3 - D image reconstruction.»
Room - temperature investigations apply several
techniques (polarization
microscopy, single - molecule imaging, emission time dependence, energy transfer, lifetime studies, and the like) to a growing array
of biophysical problems where new insight may be gained from direct observations
of hidden static and dynamic inhomogeneity.
«At the very microscopic level,» he says, «we have developed
techniques like two - photon
microscopy, which allows extremely detailed examinations
of structures and processes within cells.»
Unlike nerves elsewhere in the body, the structure
of the living corneal nerve can be seen and measured using a
technique called confocal
microscopy.
Together, these findings demonstrate that emerging noninvasive
techniques to measure corneal nerve fiber alterations such as in vivo corneal confocal
microscopy may be useful clinical tools to screen for and monitor progression
of peripheral neuropathy in HIV - infected patients.
Additionally, they used a
microscopy technique that allowed them to capture high - resolution images at different depths within the biofilms, revealing details
of their three - dimensional structures.
NSF provides state -
of - the - art imaging tools to academic labs; supports efforts to develop new
microscopy techniques; and funds training for young scientists and engineers in the field.
By using a combination
of advanced genetics, molecular approaches, and
microscopy techniques, they found that this signaling pathway is used in the adult brain in a completely novel way.
The
technique, called microenvironmental selective plane illumination
microscopy (meSPIM), uses exceptionally long, thin beams
of laser light to trigger fluorescence in a sample, causing it to glow.
Shim and his research team combined X-ray
techniques in the synchrotron radiation facility at the U.S. Department
of Energy's National Labs and atomic resolution electron
microscopy at ASU to determine what causes unusual flow patterns in rocks that lie 600 miles and more deep within the Earth.
SAY FREEZE Scientists used an imaging
technique called cryo - electron
microscopy to snap the first close - ups
of lithium dendrites, revealing them as long, needlelike crystals.
Dr. Michael Man, a postdoctoral fellow in Prof. Dani's Unit, combined the
techniques of UV light pulses and electron
microscopy in order to see electrons moving inside a solar cell.
The
technique could also be modified for
microscopy, allowing imaging
of photosynthesis inside the plant cells.
The
technique, called stimulated Raman scattering (SRS)
microscopy, generates videos
of moving cells deep inside tissue and could replace biopsies in the diagnosis
of cancers.
The
technique, called superresolution single - molecule fluorescence
microscopy, recently helped scientists at the University
of Manchester in England track natural killer (NK) cells, which help destroy cancer and viruses.
In the lab, the team mixed each strain
of K. veneficum with a species
of algae on which it preys, and recorded the three - dimensional motions
of thousands
of cells using a high - speed holographic
microscopy technique they described in 20071.
The researchers studied the diamond samples using a combination
of advanced transmission electron
microscopy techniques at EPFL's Interdisciplinary Centre for Electron
Microscopy.
Jacques Dubochet
of the University
of Lausanne in Switzerland, Joachim Frank
of Columbia University and Richard Henderson
of the MRC Laboratory
of Molecular Biology in Cambridge, England, won for their contributions to the development
of the
technique, called cryo - electron
microscopy, the Royal Swedish Academy
of Sciences announced October 4.
This achievement has been made possible by using high - resolution cryo - electron
microscopy, a
technique brought to the CNIO thanks to Óscar Llorca, director
of the Structural Biology Programme and lead author on the paper published in Nature Communications.
An X-ray
microscopy technique recently developed at the Department
of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) has given scientists the ability to image nanoscale changes inside lithium - ion battery particles as they charge and discharge.
As ICREA Prof. at ICFO Valerio Pruneri comments «the device means a major step forward for light
microscopy techniques, especially for microarray platforms since it could definitely be used as a point -
of - care tool in the diagnosis and treatment
of major diseases such as Sepsis, a critical area where fast and accurate results can translate into life changing health outcomes for individuals.
A new nanopatterning
technique combines the advantages
of near - field
microscopy with photolithography.
Using an advanced imaging
technique called intravital
microscopy, the researchers followed the movement and interaction
of HIV - infected cells in the spleen
of mice.
Applying electron
microscopy to biology was a challenge because the
technique is done in a vacuum, which can dry out and distort the shape
of proteins and other biological molecules.
But current super-resolution
microscopy techniques do not deliver spectral information, which is useful for scientists to understand the behavior
of individual molecules, as well as to enable high - quality multicolor imaging
of multiple targets.
«New X-Ray
microscopy technique images nanoscale workings
of rechargeable batteries: Method could help researchers improve battery performance.»
Backman has been studying cell abnormalities at the nanoscale in many different types
of cancers, using an optical
technique he pioneered called partial wave spectroscopic (PWS)
microscopy.
Suchita Nadkarni, an immunologist at Queen Mary University
of London, used a
technique called confocal
microscopy to snap individual photos
of nine mouse placentas.
«These factors increase the likelihood
of adoption
of the
technique in developing countries where cost, complexity and lack
of expertly trained technicians can often prohibit the use
of a polarized
microscopy technique or even traditional laboratory
microscopy as the standard
of diagnosis,» Coté says.
The researchers used Prototype Foamy Virus integrase as a model and two molecular
microscopy techniques to record viral integration complexes traveling along stretches
of target DNA in search
of insertion points.
In her 4 years at Furman University in Greenville, South Carolina, Laura Glish, a 2006 graduate, worked on collaborative projects in two different laboratories and explored a variety
of experimental
techniques, from atomic force
microscopy to synthetic chemistry and molecular modeling.
«Basically, this approach enables us to minimize the number
of samples that need to be measured with expensive
techniques such as atomic force
microscopy and transmission electron
microscopy,» Epps says.
This allowed the researchers to blow random puffs
of air at their faces, causing them to blink, and to use a non-invasive
microscopy technique to look at how the relevant Purkinje cells respond.
Using electron
microscopy tools combined with analytical spectroscopy
techniques, the researchers were able to examine the surface
of bioprocessed Martian regolith simulants in detail.
This work, with the assistance
of soil scientists at the University
of KwaZulu - Natal, has involved a suite
of techniques, including x-ray fluorescence (to provide quantitative data on minor and trace element composition), x-ray diffraction (to reveal crystal structure and parent rock types
of paint ingredients), and environmental scanning electron
microscopy (to yield qualitative data on elements present).
Described in a study published in the journal Nature Communications, this novel approach uses high - speed atomic force
microscopy (AFM) combined with a CRISPR - based chemical barcoding
technique to map DNA nearly as accurately as DNA sequencing while processing large sections
of the genome at a much faster rate.
To make their determination, researchers used a combination
of analytical
techniques, including atom probe tomography, transmission electron
microscopy and electron beam induced current.
An international team led by researchers from the U.S. Department
of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) used advanced
techniques in electron
microscopy to show how the ratio
of materials that make up a lithium - ion battery electrode affects its structure at the atomic level, and how the surface is very different from the rest
of the material.
It also utilizes new
techniques that allow three - dimensional analysis
of fluorescent embryonic skeletons, using advanced spin - disc confocal
microscopy and software.
«This is a perfect example
of why the multiple imaging and spectroscopy
techniques available in electron
microscopy make it such an indispensable and versatile tool in renewable energy research.»
Much like in an old tube television where a beam
of electrons moves over a phosphor screen to create images, the new
microscopy technique works by scanning a beam
of electrons over a sample that has been coated with specially engineered quantum dots.
«We studied a range
of authentic microfossils using the same transmission electron
microscopy technique and in all cases these reveal coherent, rounded envelopes
of carbon having dimensions consistent with their origin from cell walls and sheaths.
Two research teams have independently developed light
microscopy techniques that resolve objects on the nanometer scale, one
of which is described online in Science this week (www.sciencemag.org/cgi/content/abstract/1127344).