Sentences with phrase «of model organisms»

She is a strong advocate for basic research and the use of model organisms in biological research.

This failure makes it harder for the public to understand the value of model organism research, which in turn threatens its funding.

The technology has thus far been applied to produce spectacular proof of principle recordings of model organism embryos which capture the developing specimen at cellular resolution throughout early development.

Studies of the brains of model organisms do allow for investigations of how brain activity arises from groups of neurons and how different groups of neurons interact with each other.

Until recently, most of what scientists knew about this process came from studies of model organisms such as mice, where nearly all neurons are produced by stem cells called ventricular radial glia (vRGs) that inhabit a fertile layer of tissue deep in the brain called the ventricular zone (VZ).

Many of the model organism databases (MODs) used by members of the GSA community — including FlyBase, WormBase, SGD, ZFIN, and MGI — have been supported by NIH's National Human Genome Research Institute (NHGRI), along with others supporting human and other research — such as OMIM, the Gene Ontology Consortium, and UniProt.

In plants, the positional cloning method has been traditionally used in studies of model organisms such as rice and Arabidopsis, providing important insights into plant genetics.

Collins used a new analysis performed by NIH staff to address concerns expressed by many of the model organism researchers gathered at TAGC, particularly a 2015 analysis by Michael Wangler, Keith Yamamoto, and Hugo Bellen that suggested NIH grant support for Drosophila research is declining.

Last week at The Allied Genetics Conference (TAGC), National Institutes of Health (NIH) Director Francis Collins provided an overview of model organism support from his agency.

The project was based on gene expression data from the modENCODE project, which aims to provide the scientific community with a comprehensive encyclopedia of functional elements of the genome of model organisms.

Last week at The Allied Genetics Conference (TAGC), National Institutes of Health (NIH) Director Francis Collins provided an overview of model organism support from his...

A group of TAGC attendees concerned about the future of model organism databases took the opportunity to start #saveMODfunding on Twitter.

Moreover, it terms of morphological, physiological, and behavioral complexity Drosophila is by far the closest to humans of these model organisms, yet its genome is not substantially bigger than the least complex metazoans.

But the reason this research is so momentous has very little to do with bacteria at all, rather it signals the beginning of modeling organisms.

«The fact that the key elements of stress and stress response are conserved in zebrafish is exciting because of the many experimental advantages of that model organism,» says chemical geneticist Randall Peterson of the Massachusetts General Hospital, Harvard Medical School, Charlestown.

«Eduardo's application was... medically relevant, and yet exploited the genetics of a model organism, which is a powerful combination.

«That money changed the landscape completely in plant science,» hastening the completion of the first plant genome sequence (of the model organism Arabidopsis thaliana) and funding work on the genomes of crop species, says Dangl, who recently chaired a committee that evaluated NPGI's accomplishments and made recommendations about its future.

But Bowdidge acknowledges that genetic information from the public domain «is still incomplete for the majority of model organisms.»

The Bone Densitometer will allow astronauts to examine bone density of model organisms in space through the use of Dual - Energy X-ray Absorptiometry (DEXA) technology.

Given his training in developmental biology, Raman focused the team to seek a novel drug target on genes important to the development of model organisms — fruit flies (Drosophila) and yeast (Saccharomyces cerevisiae)-- rather than on oncogenes that transform a normal cell into a cancer cell.

«There is a lot of interest in synthetic biology — engineering bacteria to carry out interesting tasks such as producing drugs,» says Jeff Errington, director of Newcastle University's Institute for Cell and Molecular Biology, which was formed in 2004 with the aim of studying a wide range of model organisms, including bacteria and protozoa, in order to advance our understanding of fundamental cell science.

Collins also discussed funding of model organism databases, citing the open letter for support of these key resources, which had over 11,000 signatures at the time of his talk.

Major areas of emphasis include regulation in genetically modified animals, the use of model organisms and comparative functional genomics.

Leaders of the model organism communities and GSA are working together with NIH to identify solutions that will maintain the integrity of the databases and be more cost - efficient.

Our strategy is based on the combination of genetics, imaging, electrophysiology and biochemistry in the nematode Caenorhabditis elegans (for more information on C. elegans see «an overview of the model organism C. elegans»).

They next turned to a couple of model organisms with more cells — nematodes, also known as C. elegans, and fruit flies, or Drosophila.

From widening the scope of model organisms to uncovering the inner workings of cells, for molecular biologists the human genome sequence has untold potential as a final frontier for exploratory science.

Findings We present a read dataset from whole - genome shotgun sequencing of the model organism Escherichia coli K - 12 substr.

New approaches to microscopy, precision laser ablation of individual cells and capillaries, and genetic engineering of model organisms are opening new vistas for exploring the brain and how it works.

To this end, functional genomic platforms and a number of model organisms spanning from invertebrates to genetic mouse and fish models were developed to better understand processes in humans.

GSA has also emphasized the importance of the model organism databases in response to several NIH requests for information.

Many of our model organism experts continue to work at the Institute, designing and supporting the large - scale high - throughput experiments that are a feature of the Institute's genomic studies.

We have modeled the 3D genome structure of the model organism fission yeast using a genomic approach that combines the molecular biology procedure called chromosome conformation capture (3C) and next - generation DNA sequencing.

usage of model organisms to understand and exploit the mechanisms controlling stem and precursor cell generation, maintenance, activation, recruitment, proliferation, homing and differentiation,

«The whole value of model organisms is that they are lean and mean,» so once he has established his proofs of principle, ideally he will be able to use a matrix approach to efficiently tackle many rare diseases simultaneously.

Projects and projects involving a variety of model organisms can also be accommodated.

Genome sequencing, not of humans but of model organisms such as yeast and fruitfly, was in full swing by the late 1990s.

His group studies the cellular and genetic control of gastrulation movements in zebrafish, one of the model organisms studied at the institute besides Drosophila, the C. elegans worm, frogs, mice, and newts.

In his talk, Collins presented the data above with the conclusion that you're more likely to be funded at NIH if you use one of these model organisms.

This understanding can be gained from studies of model organisms, in vitro experiments, bioinformatic analyses and human genetic studies.

Furthermore, beyond the specific services provided by the centers, their federation within CELPHEDIA enables a privileged support to users, either novice or expert in the study of model organisms, thanks to a varied panel of trainings, workshops and symposiums, focused on the use of these models.

«Combining multiple sequencing techniques, we were able to generate a chromosome - level assembly of the genome, which is an uncommonly high level of architecture for an alga and similar to that of a model organism.