Sentences with phrase «of multiple antigens»

Vector design, for example insert size, expression of multiple antigens, inclusion of a signal sequence and Adenovirus backbone, will be discussed.

Not exact matches

The Cancer Vaccine Collaborative is working on treatments that target multiple cancer antigens, which should trigger a more aggressive immune response and increase the odds of defeating tumors.

This «suggests that antibodies specific for this conserved region could provide protection against multiple toxin - mediated clostridium infections and points to a generalizable strategy for generating safe vaccine antigens for this class of toxins,» they concluded.

It's hoped this latest insight will lead to the widespread use of antigen - specific immunotherapy as a treatment for many autoimmune disorders, including multiple sclerosis (MS), type 1 diabetes, Graves» disease and systemic lupus erythematosus (SLE).

Richard Vague, the event's honorary chair, took the podium to acknowledge the vast achievements of the ACC, as did Lori Alf, a multiple myeloma patient of Edward Stadtmauer, MD, chief of Hematologic Malignancies, whose cancer is in remission after receiving chimeric antigen receptor (CAR) therapy.

This approach leverages the flexibility of the ZVex vector to deliver potentially any RNA payload to DCs, including multiple conserved antigens, neoantigens, immunostimulatory molecules, and any combination of these anti-tumor agents.

By targeting antigens to B cells using monoclonal antibodies, he successfully inhibited the development of multiple sclerosis in an animal model.

The B - cells have multiple immune functions, the main ones being antibody production, antigen presentation and regulation of the function and activity of other immune cells, i.e. T - regulatory cells, NK cells and macrophages [16].

Patients may also be less likely to develop resistance to immunotherapy because of the immune system's ability to target multiple cancer antigens simultaneously, and adapt to changing cancer cells.

Using red blood cells modified to carry disease - specific antigens, a team of scientists from Whitehead Institute and Boston Children's Hospital have prevented and alleviated two autoimmune diseases — multiple sclerosis (MS) and type 1 diabetes — in early stage mouse models.

Using simulated annealing algorithms, the potential protective efficacy of antibodies to multiple antigen - combinations, and the antibody thresholds associated with protection were investigated for the first time.

In addition, because ZVex product candidates have the potential to carry the genetic material of different tumor antigens, as well as immunostimulatory molecules, we can design them to target multiple types of cancers.

The complex networks, interactions, and responses of immune cells produce diverse cellular ecosystems composed of multiple cell types, accompanied by genetic diversity in antigen receptors.

Capacity for substantial genetic payload supports multiple tumor antigens or a combination of tumor antigens and other immune stimulatory molecules, such as checkpoint inhibitors.

The new results — from trials for patients with advanced lymphoma, multiple myeloma, and pancreatic cancer — expand on Penn's work with chimeric antigen receptor (CAR) therapies, building on findings in patients with chronic lymphocytic leukemia and acute lymphoblastic leukemia dating back to the start of the first clinical trial in 2010.

We propose that the observed reductions in IgG levels in these cases can be explained by a combination of improved secretory IgA protection with enhanced regrowth of damaged villus structures» «The finding of elevated IgG concentrations to multiple foods implies an increased permeability to food antigens, and the most significant immune - challenging foods are reasonably expected to be those that elicit the most extreme IgG responses.

VANGUARD ® crLyme helps provide broad - spectrum coverage against outer surface protein A (OspA), found in the tick, and contains antigens from multiple types of outer surface protein C (OspC), found in the tick and dog.

LEUKOCELL 2 is a multiple viral antigen vaccine for vaccination of healthy cats 9 weeks of age or older as an aid in preventing persistent viremia, lymphoid tumors caused by feline leukemia virus (FeLV) and diseases associated with FeLV infection.

Wang, R., Charoenvit, Y., Corradin, G., Porrozzi, R., Hunter, R.L., Glenn, G.M., Alving, C.R., Church, P., Hoffman, S.L. Induction of protective polyclonal antibodies by immunization with a Plasmodium yoelii circumsporozoite protein multiple antigen peptide vaccine.

Le, T.P., Church, L.W.P., Corradin, G., Hunter, R.L., Charoenvit, Y., Wang, R., de la Vega, P., Sacci, J., Ballou, W.R., Kolodny, N., Kitov, S., Glenn, G.M., Richards, R. L., Alving, C.R., Hoffman, S.L. Immunogenicity of Plasmodium falciparum circumsporozoite protein multiple antigen peptide vaccine formulated with different adjuvants.