Sentences with phrase «of multiple checkpoints»

The September SIGAR report indicated that Afghan security forces had effectively closed ranks after the DoD «advocated for the closure of multiple checkpoints and consolidation of forces on fewer bases.»

Not exact matches

Speaking of checkpoint inhibitor drugs... Merck's star cancer immunotherapy treatment Keytruda is facing some troubling clinical trial incidents which have now compelled the Food and Drug Administration (FDA) to halt three studies of the drug in multiple myeloma, a rare blood cancer, after a number of patient deaths.

iTeos is now developing EOS200271 which is a synthetic, small molecule inhibitor of indoleamine 2,3 - dioxygenase (IDO1), which has demonstrated the same anti-tumour activity in multiple preclinical tumour models in combination with immune checkpoint inhibitors as competitors, but also has demonstrated superior brain penetration.

A promising avenue of clinical research in multiple myeloma is the use of immune checkpoint inhibitors.

If approved by the FDA in October for the treatment of refractory melanoma, pembrolizumab would be the first PD - 1 checkpoint inhibitor approved in its class, beating out BMS's nivolumab in the race to the finish line — or starting line, really, since both drugs will likely have multiple future uses.

Capacity for substantial genetic payload supports multiple tumor antigens or a combination of tumor antigens and other immune stimulatory molecules, such as checkpoint inhibitors.

The University of Chicago has multiple checkpoint inhibitor clinical trials underway, including studies of breast, bladder, lung, mesothelioma, head and neck cancer, and others.

Tip: Set multiple checkpoints in increments of 8 weeks.

The shift to multiple, bite - sized missions per locale vice the longer mission structure of the older games feels more in line with the mobile aspect of the game (although the lack of checkpoints within each mission can be an annoyance).

«The Cambridge Checkpoint exams, together with the progress checks, give schools, teachers, parents and pupils an educational diagnostic tool to monitor the educational progress of our Dutch bilingual pupils in multiple subjects.

LEA administrators approve access through the robust TEAL authorization process, which includes multiple levels of approval and other checkpoints to ensure strong security.

Checkpoints are multiple - choice and open - response questions on PowerMyLearning Connect that typically come at the end of a Playlists to help students and teachers assess student mastery.

I had to restart checkpoints on multiple occasions after an hour of running around trying to solve a puzzle just to realize that a portion was glitched under the map or not completely loaded.

Reaching the multiple checkpoints scattered about the stage was about the only thing to look forward to as reaching these extends your time and overall score at the end of the level.

There are multiple downloadable content packs available including free downloadable content packs such as new cars, alongside five premium downloadable content including 12 new cars, 10 checkpoint tracks, 4 wild rush circuits and even 2 off - road career events, while also being available as part of a season pass to effectively pre-order each of the content packs at a cheaper bundled price of # 19.99.

I've experienced my share of multiple deaths simply because of a small closed off space with a many traps and enemies on the screen at once, and the checkpoint system after each loss adds to a serious chunk of progression lost between stages.

For example, while there are multiple checkpoints present in each area, you can decide to completely forgo them, and instead destroy them for lots of treasure bits.

In fact, with each stage requiring a bit of to and froing for you to work out the best route to the exit, you'll find that you manage to activate multiple checkpoints, multiple times, and it is here where you'll then no doubt find yourself placed in the most awkward, unwanted situation.

I was forced to run through the same parts of the level multiple times, each less fun than the last, and for some reason this was the only course with no checkpoints.

What makes Cuphead so incredibly difficult apart from the level design and multiple enemies on screen and projectiles to manage is the lack of checkpoints.