Sentences with phrase «of mutators»

Beating the game on any difficulty will unlock a selection of mutators, and I thought I'd share a lot of them -LSB-...]

With over 3.5 billion levels to explore, dozens of mutators to bag, numerous hidden nodes, and a plethora of unlockable kits, helmets, bikes and accessories, Descenders is packed with many hours of content.

In fact, with 3.5 billion levels to explore, dozens of mutators to pick up, hidden nodes to find and a whole ton of unlockable kits, helmets, bikes and accessories, Descenders is packed with many, MANY hours of content.

Though I get a kick out of most of the mutators, the Blue Streak one is probably my favorite (check the embedded video at about 13:00).

Selection of the mutator via the D - pad activates it.

Not exact matches

Nevertheless, the mutator mice showed no signs of premature aging, such as osteoporosis, balding, or reduced fertility, the team reported online 4 March in Nature Genetics.

To see whether point mutations, which affect just one DNA base in mtDNA, are directly involved in aging, a team of researchers at the University of Washington in Seattle charted mtDNA mutation frequency in normal mice and «mitochondrial mutator» mice.

But a few had numerous somatic mutations with distinctive patterns indicative of either a mutator phenotype or a past exposure.

Generation of DJ - 1 knockout Polg mutator mice.

We tested this hypothesis by crossing DJ -1-deficient mice with mice that have similar amounts of mtDNA damage in their SNpc as aged humans (Polg mutator mice).

14) that describes the actual percentage of mtDNA deletions others have reported to occur in the Polg mutator mouse SNpc.

No evidence of dopaminergic cell death was observed in DJ -1-deficient mice with the Polg mutator mutation.

Behavioral and metabolic characterization of heterozygous and homozygous POLG mutator mice

Second, we note that in the experiments reported here, the DJ - 1 deficient Polg mutator animals all developed the accelerated aging phenotype and that in the quantitative measure of body weight the DJ - 1 - / -; PolgMT / MT group was similar to the DJ - 1 + / +; PolGMT / MT group.

In our cohort of animals, the Polg mutator genotype did not cause SNpc cell loss nor did it cause the loss of striatal TH terminals.

Previous studies have shown that aged Polg mutator mice accumulate SNpc mtDNA deletions to a similar extent as that found in the SNpc in both PD patients and aged neurologically normal controls (∼ 50 % of mtDNA molecules harboring deletions)(Bender et al., 2006; Kraytsberg et al., 2006; Perier et al., 2013).

We hypothesized that crossing DJ -1-deficient mice with Polg mutator mice in order to increase mtDNA damage in their substantia nigra would result in the degeneration of dopaminergic neurons.

The two requisite reviews of your manuscript entitled «The Polg mutator phenotype does not cause dopaminergic neurodegeneration in DJ - 1 deficient mice» have now been received.

We also found that the loss of DJ - 1 had no effect on the weight phenotype of the Polg mutator mice, that none of the nine possible combinations of DJ - 1 and Polg genotypes were embryonic lethal, and that there was not increased astrogliosis in the Polg mutator DJ -1-deficient mouse SNpc.

Use of Illumina sequencing to identify transposon insertions underlying mutant phenotypes in high - copy Mutator lines of maize

This increased mtDNA damage results in a decrease in the abundance of mitochondrial respiratory chain complex I subunits in Polg mutator brains (Hauser et al., 2014).

Additionally, we have previously detected decreased levels of respiratory chain proteins in the brains of aged Polg mutator mice from our colony, which would indicate mtDNA damage (Hauser et al., 2014).

In addition, our analysis of the brains of aged Polg mutator mice from our own colony demonstrated a loss of respiratory chain proteins, which is indicative of mtDNA damage (Hauser et al., 2014).

The game will feature a mutator system that allows players to change the rules of the match; as players rank, new mutators become available for them to use.

By completing several of the Challenges in Story Mode, you can unlock various bots and mutators for use in Instant Action multiplayer mode.

New weapons include the Cyrogun, which allows you to freeze enemies, the Mutator, of which sees the enemies mutating and eventually exploding, and finally the Atomizer will not even leave bodies, instead completely erasing them from existence.

Speedrun mode now has mutators which allow you to play speedrun mode by having a power - up of your choosing when you start the level.

This is possibly due to the way that independent developer Psyonix has supported it since release on Xbox in early 2016, with the free game modes of «Rumble», «Hoops» and «Mutator» being added as the year progressed.

When it comes to multiplayer modes, the game has it all from traditional modes such as Team Deathmacth to something more unique like Beast Mode and players can tweak the conditions of the gaming environment via mutators such as turning on friendly fire or other interesting elements.

You can choose the match type, the track, modify the mutators, change the amount of players (with support for up to 12 racers in a game), and invite friends to your lobby.

We check out one of the newly added game modes from the «Mutator Mashup» playlist in Rocket League.

Levelling up grants players access to new weapon skins, new characters, 13 crazy game mutators (a nice throwback to the Unreal Tournament series), and a ton of medals and ribbons to earn along with your achievements.

With the introduction of «Mutators,» Rocket League players will soon be able to play a variety of interesting new game - alts, including the low - gravity «Moonball» or the classic Supersonic Acrobatic Rocket - Powered Battle - Cars game modes, «Cubic» and «Time Warp,» to name just a few.

A special playlist, entitled «Mutator Mashup,» will also launch in November and these combine several preset modes into a single, randomized list of online games.

The combination of the game's fast pace, scattered weapon pickups, and dynamic mutators keep things lively and interesting.

Up to eight players can participate in a match of Nexuiz, with over 100 Dynamic Mutators available on the fly to keep players on their proverbial toes.

The November Mutator update will deliver a ton of game - changing options.

There will be over 100 options for zombie mutators, including speed, health, type of zombies, and much more.

The Titan pack adds a breadth of new content for the title, including new environments, the Titan mutator, the Greed and the Betrayal game modes, the Stealthbender vehicle, 50 new Steamworks achievements, as well as updates across the various weapons, characters, deployables, and other basic features of the IP.

Rocket League, the sports - action hit that has surprised and delighted the worldwide gaming community, will deliver an all - new, FREE update featuring «Mutators» — a cool suite of alternative presets and settings that add depth, variety, and crazy rocket - powered fun to custom games.

A look at the comments section of Rocket League's «Mutator» YouTube trailer shows a good representation of how players seem to be feeling about the update

When a Dynamic Mutator is found and goes active, players get the option to use one of three different mutators.

The car - meets - sports action hit Rocket League will be receiving a free update this November, delivering players a veritable plethora of «Mutators.»

Following in the footsteps of previous FREE additions like the «Rumble,» «Hoops,» and «Mutator» before it, Dropshot will appear as its...

It's not unusual to find that a lot of the missions might have a mutator active to alter the gameplay in some interesting or radical way; for example, falling snow balls that temporarily freeze whoever they land on, or a health bar that starts at zero and slowly increases until the opponent has landed the first punch (that's a tough one).

Another aspect of customization that adds to the variety of gameplay is the «Mutator» option.

A Mutator provides every player with a set of weapons depending on the one selected.

Also like skulls in Halo there are mutators unlocked by various game tasks that change how you face your enemy, from lack of ammo drops to tougher enemies adding an extra multiplier to your score.

New Game Mutators: Added in 20 new unlockable game mutators including Rocket Arena (all enemy guns are rocket launchers), Traditional Mode (three lives to beat a locked seed), and Game of Guns (gun changes every fiveMutators: Added in 20 new unlockable game mutators including Rocket Arena (all enemy guns are rocket launchers), Traditional Mode (three lives to beat a locked seed), and Game of Guns (gun changes every fivemutators including Rocket Arena (all enemy guns are rocket launchers), Traditional Mode (three lives to beat a locked seed), and Game of Guns (gun changes every five kills).

Considered one of Los Angeles's most innovative painters and a central figure in the city's art scene, Moses often referred to himself as a «mutator», driven less by the desire for self - expression than by an insatiable curiosity to explore and discover.