Sentences with phrase «of myeloproliferative disorder»
Relevance to practice: Identification of the Val617Phe JAK2 mutation lays the foundation for new approaches to the diagnosis, classification, and treatment of myeloproliferative disorders.
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There are a number of different types of myeloproliferative disorders.
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«We think this study now provides a comprehensive model of how thrombopoietin controls platelet production, and perhaps gives some insight into the biology and mechanism behind specific myeloproliferative disorders,» Dr Ng said.
«Microenvironment of hematopoietic stem cells can be a target for myeloproliferative disorders.»
The team has shown that the microenvironment that controls hematopoietic stem cells can be targeted for the treatment of a set of disorders called myeloproliferative neoplasias, the most prominent of which are chronic myelomonocytic leukemia (CMML), juvenile myelomonocytic leukemia (JMML), and atypical chronic myelogenous leukemia (CML).
Title: Atopic dermatitis - like disease and associated lethal myeloproliferative disorder arise from loss of notch signaling in the murine skin Authors: Dumortier A, Durham AD, Di Piazza M, Vauclair S, Koch U, Ferrand G, Ferrero I, Demehri S, Song LL, FarrAG, Leonard WJ, Kopan R, Miele L, Hohl D, Finke D, Radtke F Date: February 2010 Publication Details: PLoS One.
We investigated the role of the cytoplasmic tyrosine kinase JAK2 in patients with a myeloproliferative disorder.
Background: Human myeloproliferative disorders form a range of clonal haematological malignant diseases, the main members of which are polycythaemia vera, essential thrombocythaemia, and idiopathic myelofibrosis.
Interpretation: A single acquired mutation of JAK2 was noted in more than half of patients with a myeloproliferative disorder.
4/7/2008 From Bench to Bedside in One Year: Stem Cell Research Leads to Potential New Therapy for Rare Blood Disorder A unique partnership between industry and academia has led to human clinical trials of a new drug for a rare class of blood diseases called myeloproliferative disorders (MPD), which are all driven by the same genetic mutation and can evolve into leuk... More...
The Johns Hopkins Center for the Chronic Myeloproliferative Disorders coordinates the care of patients with PV and other related disorders and conducts research in these areas.
Myeloproliferative neoplasms (MPNs) are blood disorders in which the bone marrow makes too many of one or more types of blood cells — white blood cells, red blood cells or platelets.
Myeloproliferative neoplasms are a group of rare disorders of the bone marrow that cause an increase in the number of blood cells.
Myeloproliferative neoplasms (MPNs) are a group of related clonal hemopoietic stem cell disorders associated with hyperproliferation of myeloid cells.